Navigation Links
University of Ottawa Heart Institute Trial Finds Popular Blood Clotting Drug Does Not Improve Patient Outcomes and Increases Risk of Bleeding
Date:10/15/2008

WASHINGTON, Oct. 15 /PRNewswire/ - A popular drug used to prevent blood clotting during the treatment of severe heart attacks does not improve outcomes for patients undergoing a life-saving surgical procedure. Further, the drug - known generically as eptifibatide (pronounced ep-ti-fy-bah-tide) - also increases the risk of bleeding. The results follow a ground-breaking clinical trial conducted at the University of Ottawa Heart Institute (UOHI) which sought to determine the efficacy of a drug that is widely used but for which little clinical evidence was available to indicate a positive impact on treatment.

The three-year trial, called ASSIST, was designed to test the safety and efficacy of eptifibatide in serious heart attack patients who underwent an emergency angioplasty - called primary PCI - to open blood and oxygen flow to the heart. The study involved a total of 400 patients diagnosed with ST-Segment Elevation Myocardial Infarction (STEMI) at UOHI; 200 undergoing primary PCI using eptifibatide, and 200 who did not. The Heart Institute's trial results showed that using eptifibatide did not significantly improve patient outcomes. In fact, the study found that using the drug increased the risk of bleeding.

"We believe there is no supporting evidence to be incorporating this drug therapy for the treatment of acute STEMI patients, said Dr. Michel Le May, Director, Coronary Care Unit

Research Group, UOHI. "In fact, there is increased risk associated with its use. As a result, we expect this study will reshape our current clinical practice of medicine in managing the treatment and care of heart attack patients."

Dr. Le May presented the findings of the ASSIST trial today in Washington, D.C. at the 2008 Transcatheter Cardiovascular Therapeutics (TCT) Symposium, where interventional cardiologists from around the world gather to discuss innovative techniques and therapies in cardiovascular medicine.

About UOHI

The Universi
'/>"/>

SOURCE Ottawa Heart Institute, University of Ottawa
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Stanford University Rises to Top of 2008 Trojan(R) Sexual Health Report Card
2. LodgeNet Healthcare Signs New Agreement with NorthShore University HealthSystem
3. The Lanier Law Firm Announces Wrongful Death Lawsuit Against Rice University, Former Coach, NCAA, Others in Students Sickle-Cell Death
4. AARP: Cornell University Tops 2008 List of Best Employers for Workers Over 50
5. Staten Island University Hospital to Pay the U.S. $74 Million to Settle Claims of Defrauding Federal Health Care Programs
6. University of Washington School of Social Work and Partners for Our Children Awarded Top National Recognition
7. Harvard University recipient of Global Health Nutrition grant
8. Mayo Clinic, McMaster University Research Review Shows Internet-based Instruction Effective for Teaching Health Care Professionals
9. Delft University of Technology patent for manufacturing radio isotopes
10. University Physicians Healthcare (UPH) Selects Broadlane to Provide Comprehensive Supply Chain Services
11. PAs Smoking Ban Should Filter Into Homes and Cars Too, According to Temple University Expert
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... 31, 2014 Leelanau Peninsula’s newest winery, ... 2014 at 7788 East Horn Road in Lake Leelanau. Joining ... , Aurora Cellars is the 25th winery along the trail. ... popular wine tour events, making its trail event debut during ... , Owners David and Faye Mathia opened the boutique ...
(Date:7/31/2014)... 0-6 Pack Abs has finally been released by well ... James Vegher. Together they have launched a training program ... tone core muscles, improve posture, eliminate achy hips, and build ... to re-train the body in order to properly activate core ... Abs review, Shane Michaels, a fitness enthusiast, agrees that ...
(Date:7/31/2014)... Adventist Health System, which is comprised ... Hospital Tampa, Florida Hospital Carrollwood, Florida Hospital Connerton ... Florida Hospital Wesley Chapel, Florida Hospital Zephyrhills, Florida ... Medical Center Lake Placid and Florida Hospital Wauchula ... Wired Hospitals and Health Systems, which is based ...
(Date:7/31/2014)... July 31, 2014 Cosmetic Town has ... patients and doctors. Doctors will be able to verify ... reviews , which guarantees their authenticity. This ... the site to receive information that has been verified ... validation system allows Cosmetic Town to filter out fake ...
(Date:7/31/2014)... FL (PRWEB) July 31, 2014 Ticket ... International Champions Cup Finals tickets at the Sun Life ... Guinness International Champions Cup is now underway. Residents and diehard ... be able to watch the Guinness International Champions Cup final ... eight teams competing in the tournament have been split into ...
Breaking Medicine News(10 mins):Health News:Aurora Cellars Joins the Leelanau Peninsula Wine Trail 2Health News:Zero To Six Pack Abs System Review Exposes Tyler Bramlett And Dr. James Veghers’ New Ab Training Program 2Health News:Zero To Six Pack Abs System Review Exposes Tyler Bramlett And Dr. James Veghers’ New Ab Training Program 3Health News:Florida Hospital West Florida Region is Among the Most Wired Hospitals and Health Systems in the United States 2Health News:Cosmetic Town Improves Patient Experience Through Secure Verification of Patients and Doctors 2Health News:Guinness International Champions Cup Finals Tickets in Miami, FL Available at Ticket Down 2Health News:Guinness International Champions Cup Finals Tickets in Miami, FL Available at Ticket Down 3
... have created a non-invasive sensor that will help ... ,When a patient faces respiratory distress in the ... oxygen via a mask. But for some people ... shut down the body's breathing reflex. , ...
... the press that the drug Dasatinib has led to reduction ... , This drug is very effective in the ... previously used drug Gleevec. ,Chronic myeloid leukemia (CML) ... stage and the blast stage.,Dasatinib was tried on all these ...
... and his team from Robarts Research Institute have found ... the immune system to produce immune cells which fights ... GSK-3 which is used in the treatment of Alzheimer’s ... any toxicity or side effects. ,Cancer ...
... Jean-Pierre Le Calvez, the Communication in-charge of the Global Alliance ... New Delhi, stated that The Global Health Bonds are expected ... are the first of the kind to be released to ... facilities. ,The investors in this scheme are believed ...
... people received minor injuries from a series of explosions at ... explosions were reported to have been triggered accidentally, but the ... Hospitals NHS Trust maintained that only two people were in ... capable of irritating the eyes, making people cough, and feel ...
... cancer patients Chemotherapy Wrong. ,Blasting women with toxic ... save their lives.// The bigger the cancer or the more ... women to kill it. But this approach has undergone a ... in Europe unveiled this weekend at a conference in Texas, ...
Cached Medicine News:Health News:Wonder drug Dasatinib gives hopes to leukemia patients 2Health News:Fewer Breast Cancer Patients to Get Chemo 2Health News:Fewer Breast Cancer Patients to Get Chemo 3
(Date:7/31/2014)... , July 31, 2014  Alexza Pharmaceuticals, ... an update on its pipeline and new product ... expects to initiate a Phase 2a study of ... developed for the management of patients with acute ... Staccato -based product candidates for development - ...
(Date:7/31/2014)... 31, 2014  Decision Resources Group is launching an ... Marketrack to now include ChinaTrack; the new capabilities track ... an interactive dashboard providing detailed brand-level share tracking and ... hospital level. Other key capabilities of the ... In addition to end-user surveys of healthcare facilities, ChinaTrack ...
(Date:7/31/2014)... Iowa , July 31, 2014 For ... California , Art,s-Way Scientific has earned ... With competition in over 30 categories, MBI,s ... for MBI members, which include building manufacturers, dealers, and ... is an excellent example the capability of our team," ...
Breaking Medicine Technology:Alexza Provides Pipeline Update 2Alexza Provides Pipeline Update 3Alexza Provides Pipeline Update 4Alexza Provides Pipeline Update 5Alexza Provides Pipeline Update 6Decision Resources Group Announces First Medical Device Account Targeting Tool in China 2Art's Way Scientific Earns Prestigious Modular Building Institute Award 2Art's Way Scientific Earns Prestigious Modular Building Institute Award 3Art's Way Scientific Earns Prestigious Modular Building Institute Award 4
... Multi-national study compared FORTEO and the currently ... the treatment of Glucocorticoid-Induced Osteoporosis, INDIANAPOLIS, ... The New England Journal of Medicine, showed ... 1-34, teriparatide [rDNA,origin] injection) significantly increased lumbar ...
... World COPD Day, Physicians Urged to Use Wider Screening Criteria for ... Alpha-1 Antitrypsin ... study finds that a,higher than expected number of COPD and severe ... need for broader,criteria for AAT deficiency testing. AAT deficiency, also known ...
Cached Medicine Technology:FORTEO(R) Increased Spine Bone Mineral Density in Patients with Glucocorticoid-Induced Osteoporosis 2FORTEO(R) Increased Spine Bone Mineral Density in Patients with Glucocorticoid-Induced Osteoporosis 3FORTEO(R) Increased Spine Bone Mineral Density in Patients with Glucocorticoid-Induced Osteoporosis 4FORTEO(R) Increased Spine Bone Mineral Density in Patients with Glucocorticoid-Induced Osteoporosis 5FORTEO(R) Increased Spine Bone Mineral Density in Patients with Glucocorticoid-Induced Osteoporosis 6Study Shows Need to Test More COPD and Asthma Patients for Underdiagnosed Pulmonary Disease 2Study Shows Need to Test More COPD and Asthma Patients for Underdiagnosed Pulmonary Disease 3Study Shows Need to Test More COPD and Asthma Patients for Underdiagnosed Pulmonary Disease 4Study Shows Need to Test More COPD and Asthma Patients for Underdiagnosed Pulmonary Disease 5
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: