Navigation Links
University of Ottawa Heart Institute Trial Finds Popular Blood Clotting Drug Does Not Improve Patient Outcomes and Increases Risk of Bleeding
Date:10/15/2008

WASHINGTON, Oct. 15 /PRNewswire/ - A popular drug used to prevent blood clotting during the treatment of severe heart attacks does not improve outcomes for patients undergoing a life-saving surgical procedure. Further, the drug - known generically as eptifibatide (pronounced ep-ti-fy-bah-tide) - also increases the risk of bleeding. The results follow a ground-breaking clinical trial conducted at the University of Ottawa Heart Institute (UOHI) which sought to determine the efficacy of a drug that is widely used but for which little clinical evidence was available to indicate a positive impact on treatment.

The three-year trial, called ASSIST, was designed to test the safety and efficacy of eptifibatide in serious heart attack patients who underwent an emergency angioplasty - called primary PCI - to open blood and oxygen flow to the heart. The study involved a total of 400 patients diagnosed with ST-Segment Elevation Myocardial Infarction (STEMI) at UOHI; 200 undergoing primary PCI using eptifibatide, and 200 who did not. The Heart Institute's trial results showed that using eptifibatide did not significantly improve patient outcomes. In fact, the study found that using the drug increased the risk of bleeding.

"We believe there is no supporting evidence to be incorporating this drug therapy for the treatment of acute STEMI patients, said Dr. Michel Le May, Director, Coronary Care Unit

Research Group, UOHI. "In fact, there is increased risk associated with its use. As a result, we expect this study will reshape our current clinical practice of medicine in managing the treatment and care of heart attack patients."

Dr. Le May presented the findings of the ASSIST trial today in Washington, D.C. at the 2008 Transcatheter Cardiovascular Therapeutics (TCT) Symposium, where interventional cardiologists from around the world gather to discuss innovative techniques and therapies in cardiovascular medicine.

About UOHI

The Universi
'/>"/>

SOURCE Ottawa Heart Institute, University of Ottawa
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related medicine news :

1. Stanford University Rises to Top of 2008 Trojan(R) Sexual Health Report Card
2. LodgeNet Healthcare Signs New Agreement with NorthShore University HealthSystem
3. The Lanier Law Firm Announces Wrongful Death Lawsuit Against Rice University, Former Coach, NCAA, Others in Students Sickle-Cell Death
4. AARP: Cornell University Tops 2008 List of Best Employers for Workers Over 50
5. Staten Island University Hospital to Pay the U.S. $74 Million to Settle Claims of Defrauding Federal Health Care Programs
6. University of Washington School of Social Work and Partners for Our Children Awarded Top National Recognition
7. Harvard University recipient of Global Health Nutrition grant
8. Mayo Clinic, McMaster University Research Review Shows Internet-based Instruction Effective for Teaching Health Care Professionals
9. Delft University of Technology patent for manufacturing radio isotopes
10. University Physicians Healthcare (UPH) Selects Broadlane to Provide Comprehensive Supply Chain Services
11. PAs Smoking Ban Should Filter Into Homes and Cars Too, According to Temple University Expert
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2008)...ire-FirstCall/ -- Heska Corporation,(Nasdaq: HS...rk Society of,Security Analysts, 12th Annual Biot..., 2008 at 1177 Avenue of the Americas, 2nd Floor i...begin at 9:35 a.m. Eastern Time (7:35 a.m.,Mounta...d for two weeks,following the presentation throug...
(Date:11/21/2008)...tive against Lennox-Gastaut syndrome , ,...lled Banzel (rufinamide) has been approved as a su...y called Lennox-Gastaut syndrome, the U.S. Food an...pproval was based on results of a four-month clini...pared to patients who took a placebo, those who to...
(Date:11/21/2008).../ -- NursingCenter.com, the premier site,for onli...content, has been,updated to improve the interact...Powered by Lippincott Williams & Wilkins (LWW)...viewed continuing education activities and free,a... nursing journals.,Lippincott Williams & Wilk...
(Date:11/21/2008)...Newswire-FirstCall/ -- Today, prescription drugs a...eating 88 percent of patients suffering chronic co... a chronic condition account for 96 percent of all...medical costs. A proprietary new pharmacy model d...s, Inc. (NYSE: MHS ) significantly reduces criti...
Breaking Medicine News(10 mins):Health News:FDA Approves New Drug for Severe Epilepsy 2Health News:NursingCenter.com Launches New Features to Improve User Experience 2Health News:NursingCenter.com Launches New Features to Improve User Experience 3Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 2Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 3Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 4Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 5Health News:New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes 6
...xposure to high pollution levels can increase peop...sts in Japan have found that the risk of stroke fr...urrently breathing and heart problems are associat...t of air pollution rather than variations in hourl...
...ning music acquire better memories, literacy skill...rts. This study was conducted by// Laurel Trainor,...r at McMaster University in Hamilton, Ontario and ... of 6 children aged 4-6. They took a music test af...
... are mere actors, echoed The Bard, eons ago. As t...of this crippling disease, today on// World Alzhei... is time to take the bull by its horns and evolve ...ement of the disease. Alzheimer’s is a degenera...
...tamin shots may be beneficial in preventing severe...ts.// Presently there exists no effective treatm...serious disability is most likely to appear. The...dy appearing in the Journal of Neuroscience, and ...
Other Medicine News:Health News:Stroke Linked to High Pollution Levels 2Health News:World Alzheimer’s Day: In Memory of Those With 'Memory Loss 2Health News:World Alzheimer’s Day: In Memory of Those With 'Memory Loss 3Health News:Vitamin Shots to Combat MS Pain 2
(Date:11/20/2008)...lif., Nov. 20 Milk. It does a body...ginally thought. After years of,research, scienti...found in,cow,s milk that stimulate the body,s own...the Multimedia News Release, go to:, http://www.pr...While developing new cancer therapies, the chief s...
(Date:11/20/2008)...ss., Nov. 20 Radius Health ("Radiu...al $15 million to its second institutional financi...$82.5 million and the total amount raised since th...ing institutional investors participated in the fi...including MPM Capital, The Wellcome Trust, HealthC...
(Date:11/20/2008)...orway, November 20 The Scandinavia...has announced results of studies on its,lead anti... Washington, DC,the studies showed that the nove...ocidal effect, significantly better towards killin...s than marketed gold standard drugs. In,addition ...
(Date:11/19/2008)...tudy did not achieve statistical significance , ...l/ -- Pharmos Corporation (Nasdaq: PARS ) today ... of its topical NanoEmulsion (NE) drug delivery te...ine. , , The multi-center, randomized, doub... safety and efficacy of the Company,s 3% Diclofena...
Breaking Medicine Technology:Photos: Peptides Discovered to Alleviate Chemotherapy Side Effects 2Radius Raises Additional $15 Million, Increasing Second Private Equity Financing Round to $82.5 Million 2Lytix Presents LTX-109 Anti-Microbial Data at ICAAC 2Pharmos Announces Clinical Results from Phase 2a Trial of Topical Diclofenac NanoEmulsion Cream 2Scientists uncover a novel mechanism that regulates carbon dioxide fixation in plants 2389 1Scientists uncover a novel mechanism that regulates carbon dioxide fixation in plants 2389 2Surface dislocation nucleation 3A Strength is but skin deep at the nanoscale Penn engineers discover 3677 1Surface dislocation nucleation 3A Strength is but skin deep at the nanoscale Penn engineers discover 3677 2Viruses evolve to play by host rules according to University of Pennsylvania researchers 2387 1Viruses evolve to play by host rules according to University of Pennsylvania researchers 2387 2Ronnie B Martin DO FACOFP dist to be Inaugurated as the 55th President of the ACOFP 282008 2009 29 13349 1Ronnie B Martin DO FACOFP dist to be Inaugurated as the 55th President of the ACOFP 282008 2009 29 13349 2Ronnie B Martin DO FACOFP dist to be Inaugurated as the 55th President of the ACOFP 282008 2009 29 13349 3
...r., ,Offers an average 5:1 increase in usage time... cannula. , ,The combination of the OXYMATIC cons...oxygen patients a superior alternative to liquid o.... , ,NOTE: Each model has passed the ASTM PS ...
...r., ,Offers an average 5:1 increase in usage time... cannula. , ,The combination of the OXYMATIC cons...oxygen patients a superior alternative to liquid o.... , ,NOTE: Each model has passed the ASTM PS ...
...r., ,Offers an average 5:1 increase in usage time... cannula. , ,The combination of the OXYMATIC cons...oxygen patients a superior alternative to liquid o.... , ,NOTE: Each model has passed the ASTM PS ...
Redesigning the World's Oxygen Therapy One Device at a Time. , ,Everything you like about our OXYMATIC 400 Series conservers, only better!
Medicine Products: