Navigation Links
University of Ottawa Heart Institute Trial Finds Popular Blood Clotting Drug Does Not Improve Patient Outcomes and Increases Risk of Bleeding
Date:10/15/2008

WASHINGTON, Oct. 15 /PRNewswire/ - A popular drug used to prevent blood clotting during the treatment of severe heart attacks does not improve outcomes for patients undergoing a life-saving surgical procedure. Further, the drug - known generically as eptifibatide (pronounced ep-ti-fy-bah-tide) - also increases the risk of bleeding. The results follow a ground-breaking clinical trial conducted at the University of Ottawa Heart Institute (UOHI) which sought to determine the efficacy of a drug that is widely used but for which little clinical evidence was available to indicate a positive impact on treatment.

The three-year trial, called ASSIST, was designed to test the safety and efficacy of eptifibatide in serious heart attack patients who underwent an emergency angioplasty - called primary PCI - to open blood and oxygen flow to the heart. The study involved a total of 400 patients diagnosed with ST-Segment Elevation Myocardial Infarction (STEMI) at UOHI; 200 undergoing primary PCI using eptifibatide, and 200 who did not. The Heart Institute's trial results showed that using eptifibatide did not significantly improve patient outcomes. In fact, the study found that using the drug increased the risk of bleeding.

"We believe there is no supporting evidence to be incorporating this drug therapy for the treatment of acute STEMI patients, said Dr. Michel Le May, Director, Coronary Care Unit

Research Group, UOHI. "In fact, there is increased risk associated with its use. As a result, we expect this study will reshape our current clinical practice of medicine in managing the treatment and care of heart attack patients."

Dr. Le May presented the findings of the ASSIST trial today in Washington, D.C. at the 2008 Transcatheter Cardiovascular Therapeutics (TCT) Symposium, where interventional cardiologists from around the world gather to discuss innovative techniques and therapies in cardiovascular medicine.

About UOHI

The Universi
'/>"/>

SOURCE Ottawa Heart Institute, University of Ottawa
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Stanford University Rises to Top of 2008 Trojan(R) Sexual Health Report Card
2. LodgeNet Healthcare Signs New Agreement with NorthShore University HealthSystem
3. The Lanier Law Firm Announces Wrongful Death Lawsuit Against Rice University, Former Coach, NCAA, Others in Students Sickle-Cell Death
4. AARP: Cornell University Tops 2008 List of Best Employers for Workers Over 50
5. Staten Island University Hospital to Pay the U.S. $74 Million to Settle Claims of Defrauding Federal Health Care Programs
6. University of Washington School of Social Work and Partners for Our Children Awarded Top National Recognition
7. Harvard University recipient of Global Health Nutrition grant
8. Mayo Clinic, McMaster University Research Review Shows Internet-based Instruction Effective for Teaching Health Care Professionals
9. Delft University of Technology patent for manufacturing radio isotopes
10. University Physicians Healthcare (UPH) Selects Broadlane to Provide Comprehensive Supply Chain Services
11. PAs Smoking Ban Should Filter Into Homes and Cars Too, According to Temple University Expert
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... 700,000 people in the U.S. are living with a ... causes or risk factors, scientists are still searching for ... don,t know when, and we don,t know why people ... and CEO, American Brain Tumor Association. "It,s frustrating for ... Brain Tumor Association funds research to pursue answers to ...
(Date:7/25/2014)... Vegas, NV (PRWEB) July 25, 2014 ... the one day Online Workshop ‘Consciousness is Power’ on ... globe are invited to attend this life transforming event ... consciousness to a higher level. Few days are left ... this workshop, Mahendra Trivedi and Trivedi Masters™ Dahryn Trivedi ...
(Date:7/25/2014)... Texas (PRWEB) July 25, 2014 Yisrayl Hawkins, ... Texas, is once again stirring the pot by revealing to ... they are deceived into worshipping Satan, the devil, in his ... clever plan organized by Satan, and carried out by the ... of the Creator from the Inspired Holy Scriptures and replacing ...
(Date:7/25/2014)... July 25, 2014 Recently, the largest ... its members and found that there had been a large ... and/or HPV virus. , Living with a sexually transmitted disease ... there are many people from all around the world who ... diagnosed with one of many STDs including HSV, HPV, HIV, ...
(Date:7/25/2014)... As the category creator and world leader in healthy ... transform and improve individual lives worldwide through its exclusive and ... a successful Austin, Texas based "Xocai Activ Drink" author, is ... July to promote the up and coming mxicorp.com/company/igc Eric Worre ... has been a leader in the Network Marketing Profession for ...
Breaking Medicine News(10 mins):Health News:Brain tumor causes and risk factors elude scientists 2Health News:Mahendra Trivedi to Host an Online Workshop ‘Consciousness is Power’ 2Health News:Mahendra Trivedi to Host an Online Workshop ‘Consciousness is Power’ 3Health News:Yisrayl Hawkins Says You Have Been Tricked Into Worshipping Satan in New Article 2Health News:The Number of People Living With HSV and HPV Greatly Increased- Survey on PositiveSingles.com 2Health News:Austin, Texas Based "Xocai Activ Drink" Author, Adam Paul Green, to Visit Niigata Japan to Promote mxicorp.com/company/igc Eric Worre Speaking Engagement 2Health News:Austin, Texas Based "Xocai Activ Drink" Author, Adam Paul Green, to Visit Niigata Japan to Promote mxicorp.com/company/igc Eric Worre Speaking Engagement 3Health News:Austin, Texas Based "Xocai Activ Drink" Author, Adam Paul Green, to Visit Niigata Japan to Promote mxicorp.com/company/igc Eric Worre Speaking Engagement 4
... have identified a cell population that is a primary ... dementia//, which is as common as Alzheimer's disease in ... ,Because the cells arose only recently in evolutionary history ... humans-- and are particularly abundant in humans, and the ...
... have shown that the chemical language with which neurons ... the developing nervous system. The findings suggest that modification ... for a wide range of brain disorders. ,In ... edition of the journal Proceedings of the National Academy ...
... surprising structure and properties of a protein responsible for regulating ... binds its target RNA// -- are described by researchers from ... an essential nutrient, and defects in uptake and metabolism that ... variety of diseases and disorders, including heart disease, arthritis and ...
... sand fly, has affected an estimated 25,000 people, mostly poor, and ... 31 of the state's 38 districts in its grip. ... of the poor, the disease has affected the little son of ... to earn more money to treat his son and is working ...
... any of its organelles or protein aggregates, it envelops them ... them to another compartment, the lysosome, for digestion. ... showed that this process, called autophagy, sensitizes cells for recognition ... know how often this pathway is used or how efficient ...
... role in the immune system have revealed a surprising ... one percent of all live births//. ,"This ... ureter’s ability to pump urine from the kidney to ... professor of pathology and immunology. "If untreated, this leaves ...
Cached Medicine News:Health News:Study Offers Window into Human Behavior, Brain Disease 2Health News:Study Offers Window into Human Behavior, Brain Disease 3Health News:Study Offers Window into Human Behavior, Brain Disease 4Health News:Electrical Activity Alters Language Used By Nerve Cells 2Health News:Electrical Activity Alters Language Used By Nerve Cells 3Health News:Structure of Iron Regulatory Protein-RNA Complex Solved 2Health News:Kalaazar sweeping through Bihar, 93 dead 2Health News:Cellular Pathway Yields Potential New Weapon in Vaccine Arsenal 2Health News:Protein Essential for Kidney-to-Bladder Urine Transfer 2Health News:Protein Essential for Kidney-to-Bladder Urine Transfer 3
(Date:7/24/2014)... Germany , and MARSEILLE, France ... , Exclusive global license from University of Tokyo ... next-generation sequencing (NGS) gene panels, for blood cancers  ... new test, indicate favorable prognosis for patients with bone ... sees potential for developing companion diagnostics to guide treatment ...
(Date:7/24/2014)... Inc. (NYSE: MTD ) today announced second ... , Sales in local currency increased by ... Reported sales increased 5% which included a 1% benefit ... as reported (EPS) were $2.49, compared with $2.24 in ... an increase of 9% over the prior-year amount of ...
(Date:7/24/2014)... July 24, 2014 Omnicell, Inc. (NASDAQ: ... medication and supply management solutions and analytics software ... July 31, to discuss the Company,s Second Quarter ... Quarter 2014 earnings conference call and webcastWhen: ... Randall Lipps, chairman, president and chief executive officer ...
Breaking Medicine Technology:QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 2QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 3QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 4QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 5Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 2Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 3Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 4Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 5Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 6Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 7Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 8Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 9Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 10Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 11Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 12Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 13Mettler-Toledo International Inc. Reports Second Quarter 2014 Results 14Omnicell to Release Second Quarter 2014 Earnings Results on July 31 2
... concave seats and large backrests with ... seats, backrests, armrests, and casters and ... for top performance in a variety ... clean room, static control, health care ...
... ergonomic chairs with concave seats and ... Select options like seats, backrests, armrests, ... the BE Series for top performance ... industry, education, laboratory, clean room, static ...
... chairs with concave seats and large backrests ... seats, backrests, armrests, and casters and glides. ... performance in a variety of environments including: ... health care and office. • With reinforced ...
... with concave seats and large backrests with ... backrests, armrests, and casters and glides. • ... in a variety of environments including: industry, ... care and office. • With reinforced nylon ...
Medicine Products: