Navigation Links
University of Ottawa Heart Institute Scientists Successfully Develop Novel Biomaterial to Help Grow New Blood Vessels
Date:1/13/2009

OTTAWA, Jan. 13 /PRNewswire/ - Researchers at the University of Ottawa Heart Institute (UOHI) have successfully grown blood vessels in damaged muscle tissue by injecting a biomaterial developed specifically to attract new cells and support regeneration. Blood vessel regeneration suggests that the body's own cells might one day be used to repair heart damage and restore function.

Details of the regeneration process were published online in the Journal of the Federation of American Societies for Experimental Biology (http://www.fasebj.org/cgi/content/abstract/fj.08-111054v1). A UOHI cardiac surgery research team led by Erik Suuronen, PhD, in collaboration with Dr. Marc Ruel, showed that thigh muscles with ischemia (lack of blood flow and oxygen) grew a significant number of new blood vessels when treated with the biomaterial.

"Our goal is to develop safe and effective treatments for coronary artery disease by helping the body rebuild blood vessels and improve heart function. We see this is a breakthrough that may also positively impact diseases such as diabetes, some disorders of the liver and chronic brain ischemia," said Suuronen, principal investigator of the study and research scientist in UOHI's division of cardiac surgery.

The novel biomaterial developed by the Heart Institute combines a collagen protein and a molecule known as sialyl Lewisx. The biomaterial forms a biological platform, or 'smart scaffold,' which serves as a mechanism to support cell growth. When injected into damaged muscle, the scaffold attracts special types of cells in the bloodstream called progenitor cells. In turn, the progenitor cells send out homing signals that call other cells to join them in growing new blood vessels.

Until now, cell therapy has shown only modest improvement in helping to restore blood flow and functionality in a failing h
'/>"/>

SOURCE Ottawa Heart Institute, University of Ottawa
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. MEMOTEXT Collaborating with Johns Hopkins University To Evaluate Technology-Driven Adherence Programs
2. The Salvation Army and Rush University Medical Center Launches Keep it Fit Chicago
3. Andre Konski, M.D., M.B.A., Accepts Radiation Oncology Position at Wayne State University and the Karmanos Cancer Institute
4. Baxter and Northwestern University partner to target new life sciences projects
5. ARUP Laboratories and Weber State University Team Up to Provide Laboratory Education Solutions
6. The Leukemia & Lymphoma Society and The University of Kansas Cancer Center Announce Innovative Partnership to Accelerate Drug Development
7. Ekahau Selected to Provide RTLS to University HealthSystem Consortium
8. UCSF and Muhimbili University Launch Initiative to Strengthen Tanzanian Health Workforce
9. MEDRAD Sponsors PET Research with University of Zurich
10. UT Southwestern University Hospitals transplant program recognized for increasing organ donor rates
11. Benedictine University Launches New Online Program, Master of Science in Nursing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... April 24, 2015 Ryadon is a ... range of capabilities and services to complement any custom ... Quantity Discount Program will be offered on all heavy ... Order 4-19: Receive 10% discount - Order 20+: Receive ... the Drawer Slides Products, Furniture ...
(Date:4/24/2015)... TX (PRWEB) April 24, 2015 The Fastest ... Long, after their great success of the Xtreme Fat Loss ... industry. The fat loss blueprint that claims to help ... the attention of HealthyandFitZone.com's Stan Stevenson, prompting an investigative review. ... shows that the creators spent years researching and experimenting with ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 The 1975 ... toured almost constantly across the globe to theaters, festivals and ... in Manchester, they’ve partnered with their label, Dirty Hit Records, ... Teaming up with the newly launched Cadence & Cause ... their debut LP on vinyl and a signed photo card. ...
(Date:4/24/2015)... 24, 2015 The first step to ... mind. , For meditation and yoga teacher Stine Koppernæs, ... been invaluable tools that allow her to experience more ... has been a teacher since 2006, and through the ... state of being. , “I love sharing this way ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 Carinsurancequotesinfo.com has ... blog post explaining how to qualify for auto ... parents can qualify for auto insurance online, without having ... post explains that single parents can reduce their auto ... released article and properly explained. , Clients can ...
Breaking Medicine News(10 mins):Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 2Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 3Health News:Fastest Fat Loss Week Ever Review Revealed on Healthy & Fit Zone 2Health News:Internationally Recognized British Indie Rock Outfit The 1975 Partner with Cadence & Cause to Provide Clean Drinking Water to Those in Need 2Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2
... Kennedy To Be Honored for Leadership on Right to Health , ... ... Medical School in Boston, community members and experts join for a landmark ... U.S. and Globally., The event, which commemorates World AIDS Day and the ...
... of a new initiative to create partnerships with pediatric ... has signed a memorandum of understanding with the department ... , The memorandum is the first among Mattel ... Asia and Latin America. , ...
... American application activity for individually underwritten life insurance was down ... Index (SM). Year to date (YTD) U.S. and ... months last year. November,s activity was off -0.9% as ... U.S. application activity was down -1.8% in November ...
... Christmas Story", Ralphie sets out to convince the world that a Red ... "You,ll shoot your eye out!" was the response he got ... more hilarious and memorable quotes from this Christmas classic because we,ve all ... too many people. , , It,s hard ...
... MORTON GROVE, Ill., Dec. 5 Lifeway Foods, Inc.,(Nasdaq: ... today new distribution of its 12 pack "club pack" to the ... addition to the,expansion of the Costco Midwest region from 20 stores ... of December 2008 and consumers can,expect to find the product in ...
... tumors boosts chances for those denied under current protocols, study ... patients with liver cancer who don,t meet criteria used to ... transplantation, according to an Italian study. , The Milan criteria ... 5 centimeters or less in diameter, or three or fewer ...
Cached Medicine News:Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 2Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 3Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 4Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 5Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 6Health News:MIB Life Index Reports North American Life Insurance Activity Off 1.9% in November 2Health News:Oklahoma Parents Can Prevent Holiday Tragedies with Safe Toys and Celebrations 2Health News:Lifeway Foods Announces New East Coast and Expanded Midwest Distribution 2Health News:New Criteria Could Expand Number of Liver Transplant Candidates 2
(Date:4/24/2015)... -- Allowing more basic emergency medical service (EMS) staff ... involve opioids, according to a Centers for Disease Control ... Emergency Medical Service Providers and the Burden of Drug ... Journal of Public Health . In 2013, ... States involved prescription opioids, and more than ...
(Date:4/24/2015)... 24, 2015  New technologies and online platforms ... educate themselves about products and companies. Likewise, these ... available to market researchers seeking insights into consumer ... it,s imperative that organizations adjust their consumer marketing ... opportunities, niches and growth fronts. ...
(Date:4/24/2015)... 2015 Boston Scientific Corporation (NYSE: BSX ) ... Annual Healthcare Conference on May 6 in ... vice president and chief financial officer, and Susie Lisa ... question and answer session regarding the company with the host ... webcast of the presentation and question and answer session will ...
Breaking Medicine Technology:Expanding Naloxone use could reduce drug overdose deaths and save lives 2Expanding Naloxone use could reduce drug overdose deaths and save lives 3Pharmaceutical Industry Using New Technologies to Adjust Their Marketing and Research Approaches for Consumers 2Boston Scientific To Participate In The Deutsche Bank 40th Annual Healthcare Conference 2
... Calif., April 7, 2011 MEDomics, LLC provides ... medicine in the genomics era and is transforming ... to announce a growth capital investment from our ... from SpaGus will be used by MEDomics to ...
... Pharmaceuticals Inc. today announced that Prabhavathi Fernandes, Ph.D., president ... CHI conferences.  Dr. Fernandes will present at the ... 5 p.m. PDT, April 12, at the Hilton San ... "Macrolides as a New Class of Orally Active Anti-Inflammatory ...
Cached Medicine Technology:MEDomics Announces a Growth Capital Investment from SpaGus Ventures LLC and Gary Augusta Joins MEDomics as Chief Operating Officer 2Cempra Pharmaceuticals to Present at Two Upcoming Cambridge Healthtech Institute (CHI) Conferences 2
... The unique triple-mode technology ... all-around system for an array ... technology includes a patented, controllable ... mode for classical ablation procedures, ...
... is the only in-office test approved by the ... NMP22 BladderChek Test is a painless and non-invasive ... detects elevated levels of NMP22 protein. Healthy individuals ... in the urine. However, the level of NMP22 ...
ARION is a long-pulsed alexandrite laser system with a wavelength of 755 nm...
Used for measuring rectal pressure during urodynamic studies. All-silicone construction provides maximum softness and biocompatibility for enhanced patient comfort. Supplied sterile in peel-open pack...
Medicine Products: