Navigation Links
University of Ottawa Heart Institute Scientists Successfully Develop Novel Biomaterial to Help Grow New Blood Vessels
Date:1/13/2009

OTTAWA, Jan. 13 /PRNewswire/ - Researchers at the University of Ottawa Heart Institute (UOHI) have successfully grown blood vessels in damaged muscle tissue by injecting a biomaterial developed specifically to attract new cells and support regeneration. Blood vessel regeneration suggests that the body's own cells might one day be used to repair heart damage and restore function.

Details of the regeneration process were published online in the Journal of the Federation of American Societies for Experimental Biology (http://www.fasebj.org/cgi/content/abstract/fj.08-111054v1). A UOHI cardiac surgery research team led by Erik Suuronen, PhD, in collaboration with Dr. Marc Ruel, showed that thigh muscles with ischemia (lack of blood flow and oxygen) grew a significant number of new blood vessels when treated with the biomaterial.

"Our goal is to develop safe and effective treatments for coronary artery disease by helping the body rebuild blood vessels and improve heart function. We see this is a breakthrough that may also positively impact diseases such as diabetes, some disorders of the liver and chronic brain ischemia," said Suuronen, principal investigator of the study and research scientist in UOHI's division of cardiac surgery.

The novel biomaterial developed by the Heart Institute combines a collagen protein and a molecule known as sialyl Lewisx. The biomaterial forms a biological platform, or 'smart scaffold,' which serves as a mechanism to support cell growth. When injected into damaged muscle, the scaffold attracts special types of cells in the bloodstream called progenitor cells. In turn, the progenitor cells send out homing signals that call other cells to join them in growing new blood vessels.

Until now, cell therapy has shown only modest improvement in helping to restore blood flow and functionality in a failing h
'/>"/>

SOURCE Ottawa Heart Institute, University of Ottawa
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine news :

1. MEMOTEXT Collaborating with Johns Hopkins University To Evaluate Technology-Driven Adherence Programs
2. The Salvation Army and Rush University Medical Center Launches Keep it Fit Chicago
3. Andre Konski, M.D., M.B.A., Accepts Radiation Oncology Position at Wayne State University and the Karmanos Cancer Institute
4. Baxter and Northwestern University partner to target new life sciences projects
5. ARUP Laboratories and Weber State University Team Up to Provide Laboratory Education Solutions
6. The Leukemia & Lymphoma Society and The University of Kansas Cancer Center Announce Innovative Partnership to Accelerate Drug Development
7. Ekahau Selected to Provide RTLS to University HealthSystem Consortium
8. UCSF and Muhimbili University Launch Initiative to Strengthen Tanzanian Health Workforce
9. MEDRAD Sponsors PET Research with University of Zurich
10. UT Southwestern University Hospitals transplant program recognized for increasing organ donor rates
11. Benedictine University Launches New Online Program, Master of Science in Nursing

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/25/2009)...NFRANCISCO,Nov.25/PRNewswire/--TheBayAreaAirQualit...r Spare the Air Alert forThursday,No...logsoranyothersolidfuel,bothindoorsandoutdoors. ,...qualitytomorrow,"saidJackBroadbent,executiveoffice...spectthehealthoftheirneighborsandfellowcommunityme...
(Date:11/25/2009)...m survivors of testicular cancer who were treated ...side effects, including neurological side effects ...treated with chemotherapy, according to a new stud...the National Cancer Institute . , Marianne Brydy...niversity Hospital, in Bergen, Norway, and colleag...
(Date:11/25/2009)...uitous discovery that grew out of a collaboration ...ially offer hope to the nearly 10 million American... , Also known as hardening of the arteries, peri...latory problem in which narrowed arteries reduce b...d a red flag for vascular disease, heart attack an...
(Date:11/25/2009)...follow-up period was too short to draw definite co...Nov. 25 (HealthDay News) -- In diabetic patients w... no difference in outcomes at one year whether pat...tenting, British researchers report. , Bypass s...c patients with coronary artery disease. However, ...
(Date:11/25/2009)... Evaluation and treatment clinics t... Woodstock (Vocus) November 25, 2009 -- Centegra ...ccines and H1N1 vaccine shots at four Centegra Pri...shipment of vaccine has arrived. The clinics are a...d McHenry and will be open as follows: ,  ...
Breaking Medicine News(10 mins):Health News:Winter Spare the Air Alert in Effect for Thursday, November 26, 2009 2Health News:Engineers, doctors at UCLA develop novel material that could help fight arterial disease 2Health News:Engineers, doctors at UCLA develop novel material that could help fight arterial disease 3Health News:Engineers, doctors at UCLA develop novel material that could help fight arterial disease 4Health News:Stenting May Equal Bypass for Diabetic Heart Patients 2Health News:Stenting May Equal Bypass for Diabetic Heart Patients 3Health News:Centegra H1N1 Vaccination Clinics to Resume Tuesday, Dec. 1 2Health News:Centegra H1N1 Vaccination Clinics to Resume Tuesday, Dec. 1 3Health News:Centegra H1N1 Vaccination Clinics to Resume Tuesday, Dec. 1 4
...al economic shutdown as some 2 million public ser...pute . 'It's going to be a total shutdown tomorrow... a massive strike involving marches in major citie... warned Tuesday. The comment came after ye...
... unconscious in his Kingston hotel room on 18 Marc...orld Cup . An initial pathologist's report had con... the Pakistan team was fingerprinted before return...ent expert opinions had concluded that the origina...
...turn the tables by declaring that some recent impo... standards and destroyed them . That was apparentl...the safety of a variety of products exported by Ch... in the north-eastern part of the country have bee...
...inated with carcinogens, for thirty years, a speci... and Prevention, reveals . The soldiers based...that contained around 40 times the safety limits o...of various forms of cancers and other illnesses am...
...g vaccines for children which are permissible unde...s here Tuesday ahead of an inaugural health confer...cials from the Organisation of the Islamic Confere...lu outbreaks and outbreaks of other infectious dis...
...re than leave you short-tempered: it can also stre...r disease and death, according to a study released...ural effects of long-term sleep loss have been wel...a School of Medicine adds to a growing body of evi...
Other Medicine News:Health News:South Africa Facing Major Economic Shutdown as Health Workers are Sacked En Masse 2Health News:No Foul Play, Woolmer Died of Naural Causes, Say Jamaican Police 2Health News:China Admits Fake Blood Protein Used in Drips 2Health News:Child Vaccines a Key Issue for OIC Forum in Malaysia 2Health News:Insufficient Sleep Increases Risk of Cardiovascular Disease: Study 2
(Date:11/24/2009)..., SANDIEGO,Nov.24/PRNewswire-FirstCall/--AnadysPh...titwillpresentatthe21stAnnualPiperJaffrayHealthcar...:00a.m.PST).TheconferenceisbeingheldatTheNewYorkPa...utiveOfficerofAnadys,willprovideanoverviewofAnadys... ,, Thecorporatepresentationwillbesimultaneousl...
(Date:11/24/2009)..., POTOMAC,Md.,Nov.24/PRNewswire/--Inadditiontofam...saddedPhiladelphiajurorstoherThanksgivinggratitude....Iamsothankfultothem,"shesaidofMonday,sverdictstot...ls. ,, Wisneskiisamong12,000womennationwidewhoh...rmonetherapydrugsPremarinandPrempro.Wisneskiandthe...
(Date:11/24/2009)..., SANDIEGO,Nov.24/PRNewswire/--Accumetrics,Inc.,a...174;System,thefirstrapidandeasy-to-usediagnosticsy...tiplateletagents(e.g.Plavix®andaspirin),annou...etrics,andGregoryJ.Tibbitts,ChiefFinancialOfficero...he21stAnnualPiperJaffrayHealthCareConferencebeingh...
Breaking Medicine Technology:Anadys Pharmaceuticals to Present at the Piper Jaffray Healthcare Conference 2Maryland Woman Thankful for Wyeth Verdicts 2Accumetrics to Present at the 21st Annual Piper Jaffray Health Care Conference 2Warner Chilcott Announces Earnings Release Date and Conference Call For Second Quarter 2009 Financial Results 51693 1Michael J Fox Foundation Awards Over 242 Million for Validation of 10 Parkinsons Therapeutic Targets 4724 1Michael J Fox Foundation Awards Over 242 Million for Validation of 10 Parkinsons Therapeutic Targets 4724 2Michael J Fox Foundation Awards Over 242 Million for Validation of 10 Parkinsons Therapeutic Targets 4724 3Walking Biking to Work Pays Off 51688 1Walking Biking to Work Pays Off 51688 2
... DIEGO, April 13 Researchers from the,Barbara Ann...ted findings,showing that adding curcumin or resve...tive in preventing the growth of chemo-resistant c...ivered at the American Association,for Cancer Rese...ttp://www.newscom.com/cgi-bin/prnh/20071106/KARMAN...
... Gregory Ellison, Director of Advanced Medical Cen...r PROMETA(R), PHOENIX, April 11 With Arizona fac...Gregory Ellison, Director of Advanced Medical,Cent...treatment option that,shows high success rates and...) basis in 10 hours over five sessions. As the onl...
Other Medicine Technology:Karmanos Researchers Find Non-Toxic Agents Added to Conventional Chemotherapy Decrease Survival of Colon Cancer Cells 2Arizona Doctor Offers New Addiction Drug Treatment for Meth Addicts Showing More Than 60% Success Rate 2Arizona Doctor Offers New Addiction Drug Treatment for Meth Addicts Showing More Than 60% Success Rate 3
...UP Laboratories is a national reference laboratory...esearch and development. ARUP offers an extensive ...ts in clinical and anatomic pathology. Owned by th...nclude more than half of the nation's university t...
...UP Laboratories is a national reference laboratory...esearch and development. ARUP offers an extensive ...ts in clinical and anatomic pathology. Owned by th...nclude more than half of the nation's university t...
...UP Laboratories is a national reference laboratory...esearch and development. ARUP offers an extensive ...ts in clinical and anatomic pathology. Owned by th...nclude more than half of the nation's university t...
...UP Laboratories is a national reference laboratory...esearch and development. ARUP offers an extensive ...ts in clinical and anatomic pathology. Owned by th...nclude more than half of the nation's university t...
Medicine Products: