Navigation Links
University of Nevada School of Medicine researcher reviews muscular dystrophy therapies
Date:6/22/2012

RENO, Nev. Leading muscular dystrophy researcher Dean Burkin, of the University of Nevada School of Medicine summarizes the impact of a new protein therapeutic, MG53, for the treatment of Duchenne muscular dystrophy in an article published this week in Science Translational Medicine.

"This is a focus article in which we summarize the impact of MG53 protein therapy as a treatment option and discuss the increasing number of new protein therapeutics being developed for the muscular dystrophies, including laminin-111 developed in our laboratory," Burkin, a pharmacological researcher and associate professor, said.

The article, "A Molecular Bandage for Diseased Muscle," co-authored by Ryan Wuebbles, a post-doctoral student in Burkin's lab in the University's Center for Molecular Medicine, is a review of the current status of therapeutic developments in the muscular dystrophy research field. These therapies represent significant strides and show great promise in treatment of muscular dystrophy.

Approaches to treat Duchenne muscular dystrophy include gene replacement therapy, gene repair and myoblast cell transfer.

In a study on MG53 by Noah Weislander and colleagues, presented in the same issue of Science Translational Medicine, it was found that mice that lack MG53 developed progressive muscle weakness and exhibit defective muscle repair after exercise or injury, and that MG53 facilitates rapid membrane repair to prevent damage to normal muscle.

The study suggests that treatment in combination with other protein therapies such as Burkin's laminin-111 therapy, are likely to have synergy as well for Duchenne and other muscular dystrophies.

Burkin's published research on laminin-111, a naturally occurring protein, showed it is quickly picked up in the bloodstream of mice and prevents muscle damage, an important finding for Duchenne muscular dystrophy, the most common form of muscular dystrophy.

He recently co-hosted Myomatrix 2012, a conference for leading muscular dystrophy scientists and clinicians to explore and share their latest findings and data on treatment breakthroughs. The conference was held at the University of Nevada, Reno campus, where research by Burkin has led to a potential new therapy for muscular dystrophy.


'/>"/>
Contact: Mike Wolterbeek
mwolterbeek@unr.edu
University of Nevada, Reno
Source:Eurekalert  

Related medicine news :

1. Arizona State University secures defense contract
2. Wayne State University researcher examines proteins role in diabetic retinopathy
3. University Hospitals Case Medical Center experts present at ASCO Annual Meeting
4. Feola, at University of Kentucky, receives NIH grant to study cystic fibrosis
5. McMaster University researchers discover drug destroys human cancer stem cells but not healthy ones
6. University studies and career expectations of medical students
7. University of Minnesota startup to treat challenging bacterial infection
8. Columbia University Medical Center and NY-Presbyterian experts at APA meeting
9. University of Houston Graduate College of Social Work announces partnership with MD Anderson
10. Neuropsychologist receives University of Houstons highest faculty honor
11. Louisiana Tech University professor earns NSF Early Career Development grant
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
University of Nevada School of Medicine researcher reviews muscular dystrophy therapies
(Date:10/13/2017)... ... October 13, 2017 , ... The International Association of Eating ... excellence for the field of eating disorders, announces the opening of early registration ... Orlando, Florida at the Omni Resort at ChampionsGate. , The annual ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with ... for the primary prevention of cardiovascular diseases during the 15th Annual Women’s ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , which ... evacuation of the facility as part of a disaster drill on October 3rd. , ... and Shelton City Emergency Manager, as well as the Connecticut Long Term Care ...
(Date:10/13/2017)... ... 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills is ... vendors and unique items from across the nation, this holiday-themed event will raise funds ... by the VNA. The boutique will be open Saturday, November 4 (10:00 a.m. ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Global Healthcare ... scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare ... activity. The fun run is geared towards children of all ages; it is ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... -- According to the Centers for Disease Control and Prevention (CDC), influenza ... Care is helping communities across Massachusetts , ... no-cost* flu shots through the end of the month. *Some ... ... flu shot is by the end of October, according to the Centers ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
(Date:10/2/2017)... Denmark , Oct. 2, 2017 The Rebound ... in the struggle to reverse the tide of prescription drug ... for regulating their medicine intake and stepping down their dosage ... set to launch in December 2017; the first 100,000 people ... Learn more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology: