Navigation Links
University of Minnesota startup to treat challenging bacterial infection
Date:5/16/2012

A live biological preparation developed by University of Minnesota researchers could put a stop to an increasingly prevalent, and sometimes deadly, infection caused by the bacterium Clostridium difficile. CIPAC Limited, based in Australia with subsidiaries in California, will continue to work with the university to advance the technology to treat patients by using frozen and, eventually, encapsulated preparations.

C. difficile affects several million people and is linked to 14,000 deaths per year in the United States, according to the Centers for Disease Control and Prevention. Symptoms of C. difficile infection include fever, nausea, and diarrhea, and most often occur following a prescribed course of antibiotics. The antibiotics kill normal microbes that live in the colon, thereby making the patient more susceptible to infections such as C. difficile.

Paradoxically, while the cause of C. difficile infection is exposure to antibiotics, the infection itself is also treated using antibiotics, which can make things worse. C. difficile infections typically affect older adults in hospitals or in long-term care facilities, but is increasingly spreading into the wider community. In recent years it has become more frequent, more severe and more difficult to treat. Patients suffering from the infection require costly care -- researchers suggest it costs $2,500-7,000 to treat each patient suffering from C. difficile.(1)

"C. difficile can be suppressed with antibiotics, which have the unfortunate side effect of killing off the normal colon bacteria that offer protection against infection," says Alexander Khoruts, M.D., co-inventor and associate professor of medicine within the university's division of Gastroenterology, Hepatology and Nutrition.

"Antibiotics don't work very well because they only suppress the C. difficile. Once you remove the antibiotic, it produces more of the infection," says Michael Sadowsky, co-inventor and McKnight University professor in the Biotechnology Institute and department of Soil, Water, and Climate.

The invention, a bacterial preparation, can enable restoration of normal bacteria in the colon.

"We are very excited to be working with the University of Minnesota in commercializing a treatment that has approximately 95% efficacy," says Geoff Rosenhain, founder of CIPAC. "Our goal is to bring to market a safe, natural and effective alternative to current treatment options, and to restore the wellbeing of patients suffering from debilitating C. difficile infections."

CIPAC is working with the FDA to begin clinical trials for the preparation. The technology was licensed exclusively to CIPAC by the university's Office for Technology Commercialization.


'/>"/>

Contact: John Merritt
jmerritt@umn.edu
612-624-2609
University of Minnesota
Source:Eurekalert

Related medicine news :

1. Columbia University Medical Center and NY-Presbyterian experts at APA meeting
2. University of Houston Graduate College of Social Work announces partnership with MD Anderson
3. Neuropsychologist receives University of Houstons highest faculty honor
4. Louisiana Tech University professor earns NSF Early Career Development grant
5. Rice University student engineers automate limb lengthening for kids
6. Leading experts on congenital muscular dystrophy convene at University of Nevada, Reno
7. University of Cincinnati researchers win $3.7M grant from US Department of Defense
8. Oxford University Press partners with the Physical Society of Japan
9. Fewer women need repeat breast cancer surgeries with new service at University of Michigan
10. Kessler Foundation scientist addresses opening of science complex of William Paterson University
11. 90 percent of firefighters exhibit symptoms of PTSD according to Ben-Gurion University researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/18/2017)... (PRWEB) , ... July 18, 2017 , ... ... device compliance and commercialization, has just announced two more sessions of its “From ... engineering into risk management activities. Led by David Cronin, Cognition’s CEO, the half-hour ...
(Date:7/18/2017)... ... July 18, 2017 , ... The results of an international clinical trial, led in ... for a severe type of muscular dystrophy holds promise for a subgroup of patients. , ... McDonald and colleagues at 53 study sites in 18 countries describe the clinical benefit ...
(Date:7/18/2017)... ... July 18, 2017 , ... An inventor from Anacortes, ... "Due to menopause, I have frequent hot flashes, and I suffer from anxiety and ... way to keep cool while out and about." INSTA-FAN meets that need. , This ...
(Date:7/18/2017)... ... July 18, 2017 , ... Heritage Woods of Benton, a ... to 12:30 p.m. on Aug. 15. , The community, which is located at 1305 ... Medicaid, who need some help to maintain their independence. , The lunch menu will ...
(Date:7/18/2017)... ... 18, 2017 , ... FCPX LUT Berlin for Final Cut Pro X gives ... includes 60 different color-grade presets, giving FCPX users numerous options for adding different color ... each subject, plus much more. FCPX LUT Berlin is designed for any skill-level, from ...
Breaking Medicine News(10 mins):
(Date:6/27/2017)... Jun 27, 2017   NuEyes (NuEyes Technologies Inc.) ... to fuel its growth in helping the legally blind live ... Design Group), the leading developer of augmented, virtual and mixed ... The undisclosed funding amount was provided by strategic ... Angel, with offices in Abu Dhabi , ...
(Date:6/19/2017)... 19, 2017  Researchers from DRUGSCAN ® and ... host a live, complimentary webinar titled, "Untangling methods to ... the real world" on Wednesday June 28, 2017 from ... This webinar will feature interviews with recreational and dependent ... manipulation techniques abusers use to prepare opioid tablets for ...
(Date:6/14/2017)... 2017  ivWatch LLC, a medical device company focused ... therapy, is pleased to announce it was the Bronze ... Supplies and Equipment at the 2017 Medical Design Excellence ... industry. The award was presented by Medical Device and ... in New York during MD&M ...
Breaking Medicine Technology: