Navigation Links
University of Michigan Cardiovascular Center studies new treatment for high-risk aortic patients
Date:3/9/2011

ANN ARBOR, Mich. The University of Michigan Cardiovascular Center, a leader in heart valve replacement, will participate in a national clinical trial to offer patients a less invasive approach to replacing diseased aortic valves.

The nationally ranked U-M is among 40 sites in the nation selected for the Medtronic CoreValve U.S. Pivotal trial, a study that will examine an investigational alternative to open heart surgery for patients with severe aortic stenosis.

About 100,000 Americans, most of them over the age of 70, are diagnosed with severe aortic stenosis each year, but one-third of patients, because of age or frail health, are considered too high-risk for traditional surgery.

"Through this trial we are investigating a minimally invasive procedure for the thousands of patients diagnosed each year with severe aortic stenosis," says U-M cardiac surgeon G. Michael Deeb, the Herbert Sloan Collegiate professor of surgery. "There is a tremendous unmet need for a safe and effective treatment that will help them live longer and feel better."

It's not uncommon for patients to experience chest pain, dizziness, shortness of breath, feel faint with activity, and suffer heart palpitations. As the population ages, more Americans will be susceptible to aortic stenosis, he says.

Aortic stenosis is a condition where the aortic valve narrows, thereby limiting blood flow from the aorta to the rest of the body. Left untreated, aortic valve stenosis can lead to serious heart problems, including heart failure and even death.

The U-M study team will be lead by Stanley J. Chetcuti, M.D., associate professor of internal medicine, Paul Michael Grossman, M.D., associate professor of internal medicine, G. Michael Deeb, M.D., Herbert Sloan Collegiate professor of surgery, and Himanshu J. Patel, M.D., associate professor of surgery.

They are among the experts in the U-M aortic program that performs over 500 surgical valve procedures a year, which is more than any other Michigan program.

High volume and excellent patient outcomes contribute to the University of Michigan's heart and heart surgery programs ranking as one of the nation's best and tops in the state, according to U.S. News and World Report.

"A unique aspect of the Cardiovascular Center is that there are multiple disciplines housed in one building," says Patel, a U-M cardiac surgeon. "This collaborative atmosphere has existed for many years and raises the level of expertise we can offer patients."

In the CoreValve trial, surgeons and interventional cardiologists work together to perform the procedure called transcatheter aortic valve implantation. It allows access to the diseased aortic valve percutaneously, meaning through the skin, usually an artery in the leg, rather than through open surgery.

"There can be many advantages to that," says Grossman, study co-principal investigator and director of the cardiac catheterization laboratory at the Veterans Administration Ann Arbor Healthcare System. "Open surgical procedures are often associated with long recovery times and there are many patients who are too sick to tolerate and recover from major surgery."

The CoreValve trial will involve up to 1,200 patients nationwide who are randomly assigned to one of two treatment options: the Core Valve system or open heart surgical aortic valve replacement surgery.

Severe aortic stenosis is often unpreventable and may be related to age, buildup of calcium deposits causing narrowing, radiation therapy, medications, history of rheumatic fever or high cholesterol.

Dr. Chetcuti, the study co-principal investigator and director of the cardiac catheterization laboratory at the Cardiovascular Center says: "The critical part of the study is to make sure it is done well and that we answer the questions: Is this technology safe and does it make a difference to our patients."

The trial adds to the U-M Cardiovascular Center's tradition of research expertise. In the past five years alone, its physicians and scientists have participated in more than 700 cardiovascular clinical trials.


'/>"/>

Contact: Shantell M. Kirkendoll
smkirk@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert  

Related medicine news :

1. University Hospitals Case Medical Center testing innovative heat therapy for premature ejaculation
2. University of South Florida researchers find blood-brain barrier damaged by disease
3. University of Michigan Health System earns major grant to expand childhood obesity programming
4. University of Nevada, Reno, teams with IMMY to make new life-saving blood test
5. Stevens Dr. A. K. Ganguly receives Topliss Award Lecture from University of Michigan
6. University of Miami awarded Howard Hughes Medical Institute experiment grant
7. FDA and Georgetown University Medical Center announce partnership
8. Wayne State University researchers publish results settling multiple sclerosis debate
9. Queens University researcher connects cannabis use and sexual dysfunction
10. 1 person of 1,900 met AHAs definition of ideal heart health, says University of Pittsburgh study
11. Innovative International Healthcare Partnership established at Arizona State University
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
University of Michigan Cardiovascular Center studies new treatment for high-risk aortic patients
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: