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University of Leicester cancer researchers investigate 'smoking gun' trail
Date:10/10/2007

of a urinary biomarker of oxidative stress.

This is one of two studies where Leicester is playing a lead role. Dr. Mark D. Evans is the Principal Investigator in a Euros 60k study to better understand the sources of biomarkers of oxidative stress in urine.

Both projects are spin-offs from a larger Euros 11 million EU Network of Excellence grant (Environment, Cancer, Nutrition and Individual Susceptibility, ECNIS, www.ecnis.org) of which Professor Peter Farmer, of the Department of Cancer Studies and Molecular Medicine, is the project lead at Leicester. (see link at end of release)

Dr Evans said: These are projects addressing fundamental questions that have been, for the most part, overlooked. Being awarded these two complimentary projects, back-to-back gives us the unique opportunity to address questions that we, and others in the scientific community, have wanted to examine for many years. Likewise, this project incorporates worldwide collaborations between Leicester, Collegium Medicum in Bydgoszcz, Poland; DKFZ (the German Cancer Institute), Heidelberg, Germany; Institute of Cancer Research Sutton, U.K; Medical Institute of Bioregulation, Fukuoka, Japan; and Department of Toxicogenetics, University of Leiden, The Netherlands.

Dr Cooke said: This is a further reflection of the international status of our group within the free radical and biomonitoring community. Through these projects, we are working closely with many of the top research institutes worldwide.

Dr Cooke said Leicester would act as the hub of a worldwide network of more than 17 laboratories comparing methods of measuring damage to DNA, in urine: Once we have agreement between methods, we can apply these methods to the study of DNA damage in disease.


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Contact: Dr. Marcus S. Cooke
msc5@le.ac.uk
University of Leicester
Source:Eurekalert

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