Navigation Links
University of Colorado Cancer Center test helps reduce risk of death in advanced lung cancer
Date:10/11/2011

AURORA, Colo. (Oct. 11, 2011) Researchers at the University of Colorado Cancer Center have developed a test that identifies key biomarkers in advanced lung cancer that helped reduce the risk of death by 36 percent over a 30- month period in a recent clinical trial.

"We are moving from a one-size-fits-all model to more personalized medicine in lung cancer," said University of Colorado School of Medicine Professor Fred R. Hirsch, MD, Ph.D., a Cancer Center investigator who developed the test along with colleague Wilbur Franklin, MD. "This is a completely new paradigm in treating cancer."

The test was developed in 2003 when Hirsch and his colleagues created a scoring system ranging from 0 to 400 that identified patients with the highest levels of the protein Epidermal Growth Factor Receptor (EGFR). Those scoring over 200 had a better prognosis.

A clinical trial held in Europe known as the FLEX-study, found that 30 percent of the advanced lung cancer patients who took part had high levels of the EGFR protein identified by the University of Colorado Cancer Center test.

The trial consisted of 1,125 advanced lung cancer patients separated into two groups. One group received standard chemotherapy while the other had chemotherapy along with the drug cetuximab, an antibody that attaches to EGFR receptors atop lung cancer cells and often inhibits their growth.

The results were announced two weeks ago at the 2011 European Multidisciplinary Cancer Conference in Stockholm.

Using the Cancer Center test, the trial showed that Caucasian patients with an over expression of EGFR and treated with chemotherapy and cetuximab had a 36 percent reduction in deaths compared to the other group.

Cetuximab, or Erbitux, is primarily used to fight colo-rectal and head and neck cancers.

Hirsch, who discussed the study results at the Stockholm conference, said the test is another step toward finding the best, most eff
'/>"/>

Contact: David Kelly
david.kelly@ucdenver.edu
30-303-156-374
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related medicine news :

1. University of Virginia Health System Medical Laboratories Selects Sunquest's Specimen Collection Solution
2. Akron Institute of Herzing University Launches Its First Bachelors Degree Programs to Prepare Students for Even Greater Success in Business, Health Care and IT
3. Most pandemic plans in Ontario hospitals have not been tested: Queens University study
4. San Diego State University and BIOCOM Institute Receive $4.95 Million Grant: The BRIDGE Project, Linking Education to Employment in San Diegos Life Sciences Industry
5. Smithsonian Institution, Arizona State University announce education and research partnership
6. Untreated poor vision in elderly linked to dementia, University of Michigan study shows
7. Giarmarco, Mullins & Horton, P.C. President Joseph F. Page to Speak at University of Michigan
8. Arizona State Universitys Decision Theater offers balance to an off-kilter world
9. Forest City Announces Joint Venture with Health Care REIT for University Park Life Science Properties
10. Herzing University Online Launches Master and Bachelor of Science Degrees in Nursing
11. Nurtur Acquires ActivHealth and Wellness by Choice; Gains Exclusive Partnership with Duke University Center for Living
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... ... July 30, 2015 , ... 24/7 Care At Home, a ... San Bernardino, recently announced that the Centers for Medicare and Medicaid (CMS) have awarded ... health care providers. 24/7 Care At Home’s agency is one of three top Orange ...
(Date:7/30/2015)... , ... July 30, 2015 , ... ... expand, as the company and UCLA’s Jonsson Comprehensive Cancer Center (JCCC) ... today. With the new collaboration, OncLive’s editorial and marketing groups will help spread ...
(Date:7/30/2015)... ... July 30, 2015 , ... Glidewell Laboratories, industry-leading provider of ... magazine, its multimedia publication focused on implant dentistry, is now available in print ... 6, Issue 2, as well as past issues of the dental laboratory’s quarterly ...
(Date:7/30/2015)... ... , ... On July 23rd Clay Today Online reported the state ... large prison system, which has amassed largely enough throughout the years. Florida is the ... President Obama’s recent reduction of non violent drug offender’s prison sentences, Florida is beginning ...
(Date:7/30/2015)... ... ... Gummy smile surgeon, Dr. Alex Farnoosh, now offers comprehensive treatment ... the patented gum depigmentation treatmet. Dr. Farnoosh is a renowned dentist with decades of ... the world. , “Like treatment of any other disease or condition, making the correct ...
Breaking Medicine News(10 mins):Health News:24/7 Care At Home Earns a 5-Star Rating from the Centers for Medicare and Medicaid (CMS) 2Health News:UCLA Jonsson Comprehensive Cancer Center Teams with OncLive® as a Strategic Alliance Partner 2Health News:UCLA Jonsson Comprehensive Cancer Center Teams with OncLive® as a Strategic Alliance Partner 3Health News:UCLA Jonsson Comprehensive Cancer Center Teams with OncLive® as a Strategic Alliance Partner 4Health News:Glidewell Laboratories Puts Out Latest Issue of Dental Implant Magazine Inclusive™ 2Health News:Glidewell Laboratories Puts Out Latest Issue of Dental Implant Magazine Inclusive™ 3Health News:Glidewell Laboratories Puts Out Latest Issue of Dental Implant Magazine Inclusive™ 4Health News:Florida Questions Its Spending on Punitive Incarceration in Light of Exorbitant Costs for Non Violent Offenders 2Health News:Florida Questions Its Spending on Punitive Incarceration in Light of Exorbitant Costs for Non Violent Offenders 3Health News:Gummy Smile Dentist, Alex Farnoosh DMD, is Now Offering Comprehensive Treatment Options for Gummy Smiles 2
... WALTHAM, Mass., May 28 According to Millennium Research ... Economic Quarterly (EQ), the health care and ... of the economy; while this may be true, however, ... the impact from the downturn, although not all segments ...
... -- China Sky One Medical, Inc. ("China Sky One ... a leading fully integrated pharmaceutical company in the People,s ... Cooleman, Flemish economic representative for the North of the ... Company ("TDR"), a wholly-owned subsidiary of China Sky One, ...
... New York personal injury lawyer David Perecman questions the presence of an unfenced ... ... A girl falls 30 feet through a skylight and New York personal ... 30-foot drop has the potential to cause far more severe injuries then only ...
... ... From Constipation(1): From Connecticut to California, the United ... While it might not be surprising to learn ... the results of a new survey show just how ... In fact, while more than one-half of adults surveyed ...
... Scar Product to Receive AAD SEAL OF RECOGNITION(R)GREENSBORO, ... Dermatology (AAD) has honored Merz Pharmaceuticals with its ... sun-protection benefit. The AAD SEAL OF RECOGNITION(R) recognizes ... review of independent testing results by an independent ...
... LEHIGH VALLEY, Pa., May 28 Air Products (NYSE: ... and Chief Executive Officer John E. McGlade will be ... New York on Thursday, June 4, 2009, at 8:00 ... be available on Air Products, Investor Relations web site ...
Cached Medicine News:Health News:Although the Health Care Market is Recession-Resistant, It Is Not Recession-Immune, According to Millennium Research Group's Medtech Economic Quarterly Publication 2Health News:China Sky One Medical, Inc. Welcomes Commercial Counselor from Belgium; Looks for Business Alliance with European Companies 2Health News:China Sky One Medical, Inc. Welcomes Commercial Counselor from Belgium; Looks for Business Alliance with European Companies 3Health News:Girl Falls 30 feet through a Skylight and New York Personal Injury Lawyer David Perecman is not Falling for Excuses 2Health News:Guess What Most Americans Don't Want to Talk About (Hint: It's Not Sex!) 2Health News:Guess What Most Americans Don't Want to Talk About (Hint: It's Not Sex!) 3Health News:Guess What Most Americans Don't Want to Talk About (Hint: It's Not Sex!) 4Health News:American Academy of Dermatology Recognizes Merz Pharmaceuticals 2Health News:American Academy of Dermatology Recognizes Merz Pharmaceuticals 3Health News:American Academy of Dermatology Recognizes Merz Pharmaceuticals 4
(Date:7/30/2015)... July 30, 2015  Growth of the U.S. nonprescription ... bring former prescription users to the OTC market. Due ... forecasts robust Rx-to-OTC switch activity over the next five ... with many new brands entering the market into existing ... next five years (even those with low to moderate ...
(Date:7/30/2015)... MIAMI , July 30, 2015   ... latest update to UNI®, the world,s first operating ... simulators, is now available exclusively to Gaumard users. ... for recently launched Newborn Tory™ S2200, as well ... and monitoring of clinical measures such as EtCO ...
(Date:7/30/2015)... , July 30, 2015 What ... ? Which areas are going to grow at the ... you potential revenues to 2025, assessing data, trends, opportunities ... provides 176 tables, charts, and graphs. Discover the ... market prospects. Our new study lets you assess forecasted ...
Breaking Medicine Technology:Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 2Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 3Gaumard's Latest UNI Operating System Update Adds Performance and New Functionality 2Gaumard's Latest UNI Operating System Update Adds Performance and New Functionality 3Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 2Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 3Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 4Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 5Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 6
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: