Navigation Links
University of Arizona research on scorpion antivenom published in NEJM
Date:5/13/2009

TUCSON, Ariz. --Youngsters suffering severe nerve poisoning following a scorpion sting recover completely and quickly if a scorpion-specific antivenom is administered, according to a study conducted by researchers from The University of Arizona and reported in the May 14 issue of The New England Journal of Medicine.

The article, "Antivenom for Critically Ill Children with Neurotoxicity from Scorpion Stings," recounts a study of 15 children conducted in Tucson, Ariz., during 2004 and 2005. All of the children had been admitted to a pediatric intensive care unit following a scorpion sting and were experiencing abnormal eye movements, uncontrolled thrashing of limbs and respiratory distress, all symptoms of nerve poisoning caused by the venom of the bark scorpion.

The principal investigator of the study and lead author of the article is Leslie Boyer, MD, director of the VIPER (Venom Immunochemistry, Pharmacology and Emergency Response) Institute at The University of Arizona College of Medicine and medical director of the Arizona Poison and Drug Information Center at the UA College of Pharmacy.

In the study, eight of the children, most of whom were under 6 years, received a scorpion antivenom that is commercially available in Mexico but is considered an investigational drug in the United States and is not approved for general use by the U.S. Food and Drug Administration. The seven other study participants received a placebo (a preparation containing no medication).

The symptoms of nerve poisoning were resolved in all of the children treated with the antivenom in less than four hours, and usually within two hours. The children who received the placebo continued to experience nerve poisoning for four hours or more and required large doses of sedative medication and extended hospitalization.

"This study told us that the dangerous effects of bark scorpion venom can be reversed quickly with the right antivenom," Dr. Boyer says. "One hundred percent of the children who received it got better very quickly, meaning that using this antivenom in the emergency room will make intensive care treatment unnecessary for most patients. This is particularly important in small Arizona towns without pediatric intensive care units. By avoiding helicopter trips and intensive care stays, we can save lives and keep treatment costs down at the same time."

Andreas Theodorou, MD, a professor of pediatrics and chief medical officer of University Medical Center in Tucson, was part of the study team.

"This antivenom basically takes symptoms away in a very short time," Dr. Theodorou says. "What was a life-threatening disease that would put kids in the pediatric ICU has become, for most of them, an outpatient disease."


'/>"/>

Contact: Ginny Geib
geib@pharmacy.arizona.edu
520-626-3389
University of Arizona, College of Pharmacy
Source:Eurekalert

Related medicine news :

1. Nordstrom Beat the Bridge to Beat Diabetes Run to Temporarily Suspend Traffic in University District on Sunday, May 17
2. Belmont University Graduate Launches Healthy Soul Food Restaurant on Nashvilles Historic Jefferson Street
3. University of Minnesota Physicians Chooses MedAptus Following Comprehensive Vendor Review
4. Ross University School of Medicine Expands Clinical Rotations on East Coast
5. Statement by Joseph A. Califano, Jr., Chairman and Founder, The National Center on Addiction and Substance Abuse at Columbia University and Former U.S. Secretary of Health, Education, and Welfare, on New Report by the National Association of Boards of Pha
6. University of Miami President Donna E. Shalala, Pennsylvania Gov. Edward G. Rendell: Nurse Practitioners Are Key to Obama Health Care Reform, Call for Increased Federal Funding for Innovative Nurse-Managed Health Care
7. University HealthSystem Consortium Selects Sodexo to Provide Food and Nutrition Services
8. Grand Canyon University Recognizes Nurses
9. Medical University of South Carolina Automates Grants Allocation Process with Lombardi Business Process Management Software
10. Ajou University Hospital Becomes First in Korea to Treat Using RapidArc(TM) Radiotherapy Technology from Varian Medical Systems
11. Davis Vision, Visionworks, United Concordia Dental and Louisiana State University School of Dentistry Partner with Hands on New Orleans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... cutting edge technology to revolutionize the emergency ambulance transport experience for the millions ... aware of how Uber has disrupted the taxi industry through the use of ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to ... a new, often overlooked aspect of head lice: the parasite’s ability to live away from ... common occurrence, but a necessary one in the event that lice have simply gotten out ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health ... of their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards ... at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to ...
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
Breaking Medicine Technology: