Navigation Links
Unexpected Positive Finding Expands Potential for Quigley QR333 Drug for Diabetic Neuropathy; Findings Suggest Possible Disease Modification
Date:4/30/2009

DOYLESTOWN, Pa., April 30 /PRNewswire-FirstCall/ -- Quigley Pharma Inc., www.quigleyco.com, a wholly-owned subsidiary of The Quigley Corporation (Nasdaq: QGLY) announced today that their recently completed Phase 2 double-blinded, placebo-controlled, clinical trial of diabetic peripheral neuropathy, demonstrated a significant improvement in two key measures of distal sensory nerve function in the group treated with QR333. The compound was applied topically to the feet of subjects suffering from painful diabetic neuropathy and over the course of 12 weeks, it significantly improved both maximal conduction velocity (p=0.05) and compound sensory amplitude (p=0.05) in the sural nerve. These are well established, validated and objective electrophysiologic measures of the onset and progression of diabetic nerve damage. The mean improvement in nerve conduction velocity was 1.5 m/sec, which exceeds the change considered by thought leaders to be "clinically meaningful" in clinical studies. The sural nerve carries sensation from the feet and its pathology is the fundamental cause of foot pain and ultimately foot ulcers and amputation in some diabetic subjects.

The positive findings were detected in compliant patients (approximately 50% of the original intent to treat population) who had measurable nerve activity at both the beginning and end of the study. A more conservative analysis involving approximately 65% of the randomized subjects showed a strong, but non-significant, trend toward benefit for the QR333 treated group. Other nerves evaluated for safety purposes were unaffected. The electrophysiology testing was done as a safety measure and was of interest because of the topical application of the study drug to the area of the sural nerve.

These findings necessitate a cha
'/>"/>

SOURCE Quigley Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. University of Pennsylvania researchers find that the unexpected is a key to human learning
2. Deathways open doors to unexpected cultural practices
3. Food Allergens Show Up in Unexpected Places
4. Unexpected role: EGFR protects cancer cells from starving
5. Osteotech Announces the Unexpected Passing of Audit Committee Member Leads to Receipt of Nasdaq Deficiency Letter
6. An unexpected way to cause leukemia
7. Longer flu season and unexpected strains make prevention plan key
8. LA BioMed researcher says unexpected increase in cancer risk found
9. Leicester scientist announces unexpected and exciting advance in study of cancer type
10. Men Are Vein Too: Innovative Treatment Sparks Unexpected Consumer Trend
11. Health effects of pesticide mixtures: Unexpected insights from the salmon brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... 2014 Carepoint has been designed ... by combining an intuitive interface for recording, sending, ... service tracking and reporting features. , Hall mc ... teamed up with Rebecca de Witte to create ... organizations. , Carepoint provides seamless, real-time ...
(Date:7/14/2014)... COPENHAGEN Participation in activities that promote mental ... may help protect against the development of Alzheimer,s ... new research reported today at the Alzheimer,s Association ... , Research reported at AAIC 2014 also showed ... post-traumatic stress disorder (PTSD) may increase dementia ...
(Date:7/14/2014)... July 14, 2014 Spine Team ... complete spine care—from diagnosis to treatment and recovery. Currently ... either certified in or training for certification in The ... have recently completed the extensive program. , “We require ... McKenzie Method results in better outcomes for spine pain ...
(Date:7/14/2014)... Calgary, Alberta, Canada (PRWEB) July 14, 2014 ... the “Trusted Authority in Turning Information into Money,” ... Spotfire® Partner Network, a global program that helps ... or embed the TIBCO Spotfire® analytics platform. TIBCO ... and business intelligence software, including TIBCO Spotfire analytics, ...
(Date:7/13/2014)... July 14, 2014 Recently, TopDresses100.com, a ... a new range of multi-colored Quinceanera dresses ... spokesman, all of these colorful outfits are guaranteed to ... discounts, up to 68% off. , TopDresses100.com has a ... from, and all its items are in stock and ...
Breaking Medicine News(10 mins):Health News:Home Health Care Professional and Marketing Firm Team Up to Create New Homecare Communication App 2Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 2Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 3Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 4Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 5Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 6Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3Health News:Cadeon Associates Inc. Joins TIBCO Spotfire Partner Network 2Health News:Cadeon Associates Inc. Joins TIBCO Spotfire Partner Network 3Health News:Cheap Multi-colored Quinceanera Dresses From TopDresses100.com 2
... 24 Prime Therapeutics (Prime), a,thought leader in ... has joined the organization as Vice President of,Pharmacy ... Trade Relations, Wan will focus on,developing and maintaining ... efforts in the development of strategic pharmacy,contracts and ...
... Experts offer advice on how to use the Internet to ... Internet offers a dizzying amount of health information -- whatever ... it somewhere on the Web. , But all that information ... up heeding the wrong voice and getting some fairly bad ...
... Fla., April 24 Life Brokerage Partners,announces three ... Inc. ("Peachtree"), Polaris and United National Finance,Inc. ("UNF"). ... agents because they provide new methods for transacting,business., ... Peachtree, Polaris and UNF,do not end with the ...
... STAAR Surgical,Company (Nasdaq: STAA ) today announced ... ended March 28, 2008 on Tuesday, May 6, 2008,after ... call and webcast,on Tuesday, May 6, 2008 at 5:00 ... current corporate developments. The dial-in number for,the conference call ...
... Trend Expert Addresses Impact of Technology on Health; Fitness Expert ... Denise Austin Offers Nightly Wellness Tips, MORRIS ... do you reach for your cell phone or your gym bag? ... Antiseptic,shows that Americans are busier than ever before, often at the ...
... MIAMI, April 24 Physicians Healthcare,Management Group, Inc. ... organizations (HMOs) in partnership with physicians,today announced that ... signed an agreement with Advantica EyeCare to provide,comprehensive ... be launched in,the latter half of 2008., ...
Cached Medicine News:Health News:The 'Net: A Tangled Web of Health Information 2Health News:The 'Net: A Tangled Web of Health Information 3Health News:Life Brokerage Partners Strengthens Premium Finance Programs 2Health News:STAAR Surgical Announces First Quarter 2008 Earnings Release Date and Conference Call 2Health News:Wired, Working Americans Let Nighttime Health Routines Slide 2Health News:Wired, Working Americans Let Nighttime Health Routines Slide 3Health News:Wired, Working Americans Let Nighttime Health Routines Slide 4Health News:Phyhealth Signs Agreement with Advantica EyeCare to Provide Vision Services for Pilot HMO 2
(Date:7/14/2014)... VEGAS , July 14, 2014 BioAdaptives, ... Epling , Chairman has assumed the roles of President ... owner of Ferris Holding, Inc., the company that licensed ... Inc. and its financial supporter. "Mr. ... from our early transition as a privately held entity ...
(Date:7/13/2014)... , July 13, 2014 ... Tokio veranstalteten F&E-Tagung ... Bemühungen zur Neuausrichtung seines Forschungsrahmenprogramms. Die Tagung ... über die fortgeschrittenen klinischen Programme und die ... der Tagung bestand darin, aktuelle Meldungen zu ...
(Date:7/11/2014)... 2014 The consumer marketing playbook and ... sectors to better identify winning tools and techniques. ... with and understand consumers, as new technologies are ... purchasing decisions. According to recent ... area where organizations can observe a deep pool ...
Breaking Medicine Technology:BioAdaptives Prepares for Next Step 2Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 2Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 3Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 4New Technologies Transforming Consumer Marketing Research Playbook 2
... 2011 Hologic, Inc. (Hologic or the Company) (NASDAQ: ... supplier of premium diagnostic products, medical imaging systems and ... women, today announced that Rob Cascella, Hologic,s President and ... Market Opening Bell Ceremony marking the start of Breast ...
... Leading events organiser UBM Conferences , a division ... the newly introduced CPhI Lunchtime Education Series to be ... flagship CPhI Worldwide event which is focused on pharmaceutical ... in a workshop format with six interactive sessions over ...
Cached Medicine Technology:Hologic to Preside Over NASDAQ Opening Bell Ceremony Marking the Start of Breast Cancer Awareness Month 2Hologic to Preside Over NASDAQ Opening Bell Ceremony Marking the Start of Breast Cancer Awareness Month 3Hologic to Preside Over NASDAQ Opening Bell Ceremony Marking the Start of Breast Cancer Awareness Month 4CPhI Conferences Introduces New Lunchtime Education Series 2
...
...
...
... Manager in an easy way to eliminate ... lot of money. This Windows-based tool dramatically ... the clinic, and the hospital emergency department. ... sort ECGs. Review high-resolution waveforms on-screen. Edit ...
Medicine Products: