Navigation Links
Understanding Alzheimer’s: Genetic search uncovers five new genes
Date:4/3/2011

mmune system, for example - and it's telling us there's something different about the immune system of people who go on to develop Alzheimer's disease. So their immune response or inflammatory response within the brain is different in Alzheimer's disease.

"Some of the genes are also implicating the processing of cholesterol and lipids in the brain as increasing the risk of developing the disease.

"But what's most exciting is a new area of research which refers to a process called endocytosis - which is basically the way a cell brings in big molecules from outside, inside and processes them in a very specific way.

"We now have four genes that implicate this very precise process and it offers a very big clue that this process is playing a strong role in the development of Alzheimer's disease."

This is not the first time Professor Williams and her team have made such significant gene discoveries. In 2009, she led the largest genetic investigation of Alzheimer's ever conducted, which involved analysing the DNA from more than 16,000 individuals over two years which uncovered new genes closely linked to the illness.

Professor Williams adds: "This study, plus our previous studies, means that we are beginning to piece together the pieces of the jigsaw and gain new understanding. We still have a long way to go but the jigsaw is beginning to come together.

"If we were able to remove the detrimental effects of these genes through treatments, we hope we can help reduce the proportion of people developing Alzheimer's in the long-term."

Common Variant at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease is published in Nature Genetics(Embargo: 18.00 (GMT) Sunday 3rd April, 2011) and is funded by the Wellcome Trust, Medical Research Council, Alzheimer's Research UK and the Welsh Assembly Government.

Rebecca Wood, Chief Executive of Alzheimer's Research UK said: "UK s
'/>"/>

Contact: Chris Jones
JonesC83@cf.ac.uk
44-292-087-4731
Cardiff University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Exploring the limits: Understanding the challenges facing Winter Olympic champions
2. MRC scientists announce advance in understanding bodys natural defenses
3. Health Occupations Students of America, Inc. and the U.S. Army Sign Memorandum of Understanding in Support of Improving Career Options for Nations Students
4. Understanding causes of cancer and chronic disease: The Canadian Partnership for Tomorrow Project
5. Study Makes Strides in Understanding Ovarian Cancer
6. Researchers make advances in understanding causes, treatments and outcomes of liver disease
7. Existence Genetics is Pioneering the Field of Predictive Medicine - Nexus Technologies Critical in Understanding and Preventing Deadly Disease
8. Understanding the relationship between bacteria and obesity
9. Rochester advances understanding of deadly form of malaria
10. Understanding Back Pain May Improve Management, Study Suggests
11. FSU study takes novel approach to understanding pituitary function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... Maureen Salamon HealthDay Reporter , ... in vitro fertilization (IVF) are only about half as likely ... reproduction technique, new research indicates, and the racial disparity persists ... about 31 percent of white patients became pregnant after IVF, ... more than 4,000 IVF cycles over two years to tease ...
(Date:10/22/2014)... Maureen Salamon HealthDay Reporter ... crucial part of conventional in vitro fertilization (IVF) -- the ... take place in a device inside the vagina, new research ... that the device, called an INVOcell, might sharply cut costs ... make the technology more accessible to those who don,t live ...
(Date:10/22/2014)... Thompson HealthDay Reporter TUESDAY, Oct. ... with Ebola while working for NBC News in Liberia ... special isolation unit at Nebraska Medical Center in Omaha, where he ... Tuesday. A blood test confirmed by the U.S. Centers for ... home to Providence, R.I., NBC News reported Tuesday night. ...
(Date:10/20/2014)... Allegheny General Hospital’s (AGH) Cardiovascular Institute ... to repair a damaged mitral valve as the heart ... developed by Abbott Vascular , is designed to ... condition in which the heart’s mitral valve leaflets fail ... the heart’s left ventricle into the left atrium. The ...
(Date:10/20/2014)... Women’s health specialist, Dr. Amber Murphy, MD, Ob/Gyn ... Inc., A Division of MaternOhio Clinical Associates, Inc., who ... patients annually. Dr. Murphy will provide a full range ... women’s life. She is accepting new patients at two ... , Dr. Murphy offers a wide variety of services ...
Breaking Medicine News(10 mins):Health News:Black Women Fare Worse With Fertility Treatments, Study Says 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 4Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 2Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 3Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3
... feasibility of introducing health smart cards to ensure better ... of State for Health and Family Welfare Panabaka Lakshmi ... implementing the health smart cards," the minister told the ... pilot study was initiated in the capital in March ...
... Fund (UNFPA) Thoraya A Obaid said that Bangladesh has ... many challenges to address in the health sector to ... in population controlling, reducing child and maternal motility rate, ... education and primary healthcare services Bangladesh has showed remarkable ...
... of particles which are very small. They are submicroscopic ... // The petition was raised by environmental groups which ... its regulation of sunscreens that contain nano-sized titanium dioxide ... inflammatory and immune responses in the human body. These ...
... would rather give up a year of their life rather ... online survey conducted by the Rudd Center for Food Policy ... varying numbers between 15% and 30% also said they would ... of having children, be depressed, or become alcoholic rather than ...
... Cellular damage induced by oxygen free radicals may be ... new study. //This groundbreaking study conducted by neuroscientists at ... of complex I, a protein that plays a major ... has been blamed for cellular damage in Parkinson’s disease. ...
... ailment called economy class syndrome, that is associated with the ... due to cabin environment, //as it is thought to be, ... that clots could form in healthy people, while sitting in ... in the legs, which lead to the formation of clots. ...
Cached Medicine News:Health News:Government Considering Of Issuing ‘Smart Cards’ For HIV/AIDS Patien 2Health News:Bangladesh Progressing But Must Yet Face Challenges In Health Sector 2Health News:Fat People Claim That They Would Give Their Limb Or Life Rather Than Being Fat 2Health News:Oxygen-Induced Damage A Leading Cause For Parkinson’s Diseas 2
(Date:10/22/2014)... Oct. 21, 2014   BioNano Genomics , ... genomics research centers to purchase an Irys™ System ... National Cancer Institute (NCI), NIH Intramural Sequencing Center (NISC) ... Irys, obtaining a comprehensive view of a genome ... (NGS) does not deliver the scalability or reliability ...
(Date:10/22/2014)... 2014 InVivo Therapeutics Holdings Corp. (OTCQB: NVIV) ... revolutionizing spinal cord injury (SCI) treatment with their novel ... in tissue regrowth in the spinal cord area when ... FDA approved polymer, the scaffold ultimately breaks down to ... human body. NVIV has recently attracted significant investor attention ...
(Date:10/22/2014)... Calif. , Oct. 22, 2014  AcelRx ... announced that results from the  IAP310 study have ... Medicine (RAPM), a peer-reviewed journal with broad, ... 3 trial evaluating the safety and efficacy of ... tablet system (SSTS), for the treatment of post-operative ...
Breaking Medicine Technology:BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 2InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 3AcelRx Announces Publication of Zalviso Phase 3 Abdominal Trial Results 2
Hudson Drill hand drill....
Hudson Brace, snap lock chuck....
Binocular operation microscope with innovative mechanism for smooth operation....
... has pioneered the development of ... system, an innovative solution that ... efficient and less invasive. The ... the OME-7000 surgical microscope, the ...
Medicine Products: