Navigation Links
Umbilical cord could be new source of plentiful stem cells, say Pitt researchers
Date:12/17/2009

PITTSBURGH, Dec. 17 Stem cells that could one day provide therapeutic options for muscle and bone disorders can be easily harvested from the tissue of the umbilical cord, just as the blood that goes through it provides precursor cells to treat some blood disorders, said University of Pittsburgh School of Medicine researchers in the online version of the Journal of Biomedicine and Biotechnology.

Umbilical cord tissue cells can be expanded to greater number, are remarkably stable and might not trigger strong immune responses, said senior investigator Bridget M. Deasy, Ph.D., assistant professor in the Department of Orthopaedic Surgery, Pitt School of Medicine. The cells are obtained from the gelatinous material in the cord known as Wharton's jelly and from blood vessel walls.

"Our experiments indicate also that at least 21 million stem cells, and possibly as many as 500 million, could be banked from a single umbilical cord after the birth of a baby," she noted. "So, the cord could become an accessible source of a multitude of stem cells that overcomes many of the restrictions, such as limited quantity as well as donor age and donor sex issues, that come with other adult stem cell populations."

Dr. Deasy and her team analyzed sections of two-foot-long human umbilical cords that were donated for research, looking for cells in Wharton's jelly and blood vessel walls that displayed the characteristic protein markers found in stem cells derived from other sources. The researchers then sought to find the best way to isolate the stem cells from the cords, and tested them in the lab to confirm their ability to produce specialized cells, such as bone and cartilage, while retaining their invaluable ability to renew themselves.

To build on these findings, the team will test the umbilical cord stem cells in animal models of cartilage and bone repair, as well as muscle regeneration.


'/>"/>

Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Related medicine news :

1. Private umbilical cord banking not cost-effective, UCSF research shows
2. Survey: Few physicians support private banking of umbilical cord blood
3. Umbilical cord protein analysis detects early onset infection
4. Heart Valves Fashioned From Stem Cells in Umbilical Cord Blood
5. BioLife Solutions to Supply CryoStor(TM) to Cryobanks International as Standard Media for Preservation and Storage of Umbilical Cord Blood Stem Cells
6. Stem cells from umbilical cord used in the treatment of hepatic diseases
7. Umbilical cord blood cell transplants may help ALS patients
8. Cord Blood America Says Pennsylvania Joins New York and California in Informing Parents of the Advantages of Umbilical Cord Blood Storage
9. Health risks, benefits come with delayed umbilical cord clamping
10. Injection of human umbilical cord blood helps the aging brain
11. Cord Blood America Supports Trend From New York, California for States to Inform Parents of the Advantages of Umbilical Cord Blood Storage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... Calif. (PRWEB) , ... March 24, 2017 , ... ... raised over $100,000 for its innovative EcoQube Frame vertical micro-veggies garden on ... instant demand for the product – with nearly 2,000 consumers (and counting) already ...
(Date:3/24/2017)... ... March 24, 2017 , ... The law firm of Enea, ... pleased to announce Westchester resident Lauren C. Enea has joined the firm as an ... will concentrate her practice in elder law, Medicaid planning and applications, and Wills, Trusts ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... Certified Medical Reiki™ Master in Frederick, MD. Judy says, “I am passionate about ... what is often a very difficult and challenging time.” , A Certified Medical ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... inspiring stories about real people of God in congregations across the United States. ... a Presbyterian minister ordained in 1964 who has served congregations in seven states ...
(Date:3/23/2017)... ... , ... The physicians of KSF Orthopaedic Center PA are proud to announce ... is located at 2255 E. Mossy Oaks Rd., Suite 440, Spring, Texas 77389 inside ... patients living in the north Houston area (The Woodlands, Conroe, Magnolia, Kingwood, Humble) with ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... DUBLIN , Mar 24, 2017 Research ... in Drug Discovery and Diagnostics, 2017 - 2035" report to ... The ... current landscape and future outlook of the growing market of deep ... data revolution, deep learning algorithms have emerged as a novel solution ...
(Date:3/24/2017)... 24, 2017 Today Stock-Callers.com have issued ... are: Neovasc Inc. (NASDAQ: NVCN), Hologic Inc. (NASDAQ: HOLX), Edwards ... SSH ). These companies are part of the Healthcare ... Thursday, March 23 rd , 2017, with the NYSE Health ... health care companies in the S&P 500 were down about ...
(Date:3/24/2017)... INDIANAPOLIS , March 24, 2017  Eli ... today announced plans to invest $850 million in ... span facilities across its U.S. enterprise, including research ... The investments are being driven by demand for ... of potential medicines in development targeting cancer, pain, ...
Breaking Medicine Technology: