Navigation Links
Ultrasound measurement of fetal adrenal gland a better predictor of preterm birth
Date:2/4/2010

CHICAGO, Ill. (February 4, 2010) In a study to be presented today at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting , in Chicago, researchers will unveil findings that show that measuring the fetal zone of the adrenal gland is a better predictor of pre-term birth than measuring cervical length.

Researchers with the University of Maryland and Yale University have followed up on early research that they conducted using 3D ultrasound methods.

"We previously discovered that 3D adrenal gland volume (AGV) is a very accurate predictor of preterm birth," said Dr. Ozhan Turan, the study's author. "However most people around the world don't have access to that technology, therefore, we have created measurements that can be done with 2D ultrasound that are very effective to predict pre-term birth."

In the study, patients presenting with preterm labor symptoms had ultrasound measurement of the cervical length (CL) and fetal adrenal gland dimension. Using 3D ultrasound with VOCAL cAGV (AGV/ Estimated fetal weight), 2D depth of the whole-gland (D) and fetal zone (d) were measured. The d/D ratio was calculated as an index of FZE. The cAGV, d/D and CL were compared for prediction of preterm birth within seven days.

Sixty-two singletons with preterm labor at 23-37 wks gestation were studied. Measurement-to-delivery interval only correlated with cAGV and d/D (r=-0.32 p=0.011 and r=-0.47 p=0.001respectively) but not CL (p=0.83). Twenty women had preterm birth at less than seven days (Group A) while 42 (Group B) delivered in seven days or more from initial assessment. While CL was similar (p=0.5) cAGV and d/D were higher in group A (p< 0.0001 for both). ROC area under the curve was significantly greater for cAGV and d/D than for CL (0.82, 0.91 and 0.59, p< 0.01 and 0.001 respectively, fig) without any significant differences between adrenal gland measurements. Using ROC derived cutoffs for preterm birth in less than seven days was best predicted by d/D and cAGV but not CL.

"Prior to this we haven't had a good method to predict who will present with pre-term labor." said Dr. Turan. "Measuring the cervical length leads to a high percentage of false positives and also it has limited sensitivity," he continued. "Hopefully, if adopted, this method will allow for an easy inexpensive way to identify real pre-term deliveries. Therefore we will be better managing these pregnancies."


'/>"/>

Contact: Vicki Bendure
vicki@bendurepr.com
202-374-9259
Society for Maternal-Fetal Medicine
Source:Eurekalert

Related medicine news :

1. Analysis Examines Ultrasound Use for Blood Clots
2. Lodewijk de Vink Elected to Board of Focused Ultrasound Surgery Foundation
3. Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
4. Annual Screening With Breast Ultrasound or MRI Could Benefit Some Women
5. Targeted Breast Ultrasound Can Reduce Biopsies for Women Under Forty
6. Targeted breast ultrasound can reduce biopsies for women under 40
7. Annual screening with breast ultrasound or MRI could benefit some women
8. Ultrasound With Elastography May Cut Down on Biopsies
9. Special ultrasound accurately identifies skin cancer
10. Special Ultrasound Accurately Identifies Skin Cancer
11. Simulated training for ultrasound-guided procedures improves safety without risk to patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... now treating sleep apnea using cutting-edge Oventus O2Vent technology. As many ... sleep disorder characterized by frequent cessation in breathing. Oral appliances can offer significant ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
(Date:10/12/2017)... ... , ... HMP , a leader in healthcare events and education, today announced ... Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie ... competition recognizes editorial and design excellence across a range of sectors. This year’s program ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017   Montrium ... Master File solutions, today—from the IQPC Trial Master ... , NL)—announced that EastHORN Clinical Services has ... clinical programs and TMF management. EastHORN, a leading ... eTMF platform to increase transparency to enable greater ...
(Date:9/23/2017)... -- Janssen Biotech, Inc. (Janssen) announced today that it ... Food and Drug Administration (FDA) for the Biologics License ... of moderately to severely active rheumatoid arthritis (RA). The ... to further evaluate the safety of sirukumab in the ... "We are disappointed by ...
(Date:9/22/2017)... , Sept. 22, 2017 AVACEN Medical ... device is now successfully helping those with the widespread ... Fibromyalgia diagnosed Amanda in Essex, England ... and washing my hair, experiencing no sleep at all, ... painful spasm… I cannot recommend [the AVACEN 100] enough, ...
Breaking Medicine Technology: