Navigation Links
UTMB study identifies women at higher risk of significant bone loss on injectable birth control
Date:12/21/2009

GALVESTON, Texas Nearly half of women using depot medroxyprogesterone acetate (DMPA), commonly known as the birth control shot, will experience high bone mineral density (BMD) loss in the hip or lower spine within two years of beginning the contraceptive, according to researchers at the University of Texas Medical Branch at Galveston.

The study, reported in the January 2010 issue of Obstetrics and Gynecology, was the first to show that women on DMPA who smoke, have low levels of calcium intake and never gave birth are at the highest risk for BMD loss. The researchers also found that high risk women continued to experience significant losses in BMD during the third year of DMPA use, especially in the hip the most common facture site in elderly women.

DMPA is an injected contraceptive administered to patients every three months. According to the American College of Obstetricians and Gynecologists, more than two million American women use DMPA, including approximately 400,000 teens. DMPA is relatively inexpensive compared with some other forms of birth control, has a low failure rate and doesn't need to be administered daily, which contributes to the contraceptive's popularity.

"Bone mineral density loss is not a significant concern for all women who choose DMPA," says senior author Dr. Abbey Berenson, professor in the department of obstetrics and gynecology and director of the Center for Interdisciplinary Research in Women's Health at UTMB.

According to Berenson, over the last several years there's been a fair amount of confusion about how to counsel patients. "Based on these findings, clinicians have the information they need to recommend basic behavior changes for high risk women to minimize BMD loss," she said.

The study followed 95 DMPA users for two years. In that time, 45 women had at least five percent BMD loss in the lower back or hip. A total of 50 women had less than five percent bone loss at both sites during the same period.

By and large, BMD loss was higher in women who were current smokers, had never given birth and had a daily calcium intake of 600 mg or less far below the recommended amounts. Moreover, BMD loss substantially increased among the women with all three risk factors. Age, race or ethnicity, previous contraceptive use and body mass index were not associated with higher BMD loss.

The researchers followed 27 of the women for an additional year and found that those who experienced significant BMD loss in the first two years continued to lose bone mass.

"These losses, especially among women using DMPA for many years, are likely to take an extended period of time to reverse," says first author Dr. Mahburbur Rahman, assistant professor in the department of obstetrics and gynecology and Center for Interdisciplinary Research in Women's Health.

The researchers note that while this study will help physicians counsel women with modifiable risk factors who wish to use DMPA, prevention of bone loss while using the contraceptive and reversibility of BMD loss are still not well understood and further research is needed.


'/>"/>

Contact: Kristen Hensley
409-772-6397
University of Texas Medical Branch at Galveston
Source:Eurekalert

Related medicine news :

1. With Cardiac Rehab, More Is Better: Study
2. Study shows health care spending spurs economic growth
3. New study explores role of sexual, social behaviors in seniors well-being
4. Sex in university may be better for mature audiences: study
5. Cardiome Announces Investigational Candidate, Vernakalant, Meets Primary Endpoint in European Comparator Study
6. New Study Shows No Medicare Savings if Congress Moves Against Physician Owned Hospitals.
7. NIH awards La Jolla Institute $18.8 million for major infectious disease study
8. U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines
9. New study links DHA type of omega-3 to better nervous-system function
10. New Study Reveals Pistachios Have Anti-Inflammatory Properties
11. Sleep Study Shows Pillo1 Re-Educates Body to Naturally Move Into Optimal Sleep Position and Increases REM Sleep by 21.3%
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... ... professionals, announced today its affiliation with Tennessee Counseling Association. This new ... network of the Tennessee Counseling Association, adding exclusive benefits and promotional offers. , ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, ... Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility ... home to some of the world’s leading providers of cereal and other breakfast foods. ...
(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, ... and his M.D from the David Geffen School of Medicine at UCLA. He trained ... Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Those who ... with these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, ... Marne, Michigan, has released tools for healthy coping following a traumatic event. , Trauma ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... HILLS, Calif. , June 23, 2016 Any ... the many challenges of the current process. Many of them ... because of the technical difficulties and high laboratory costs involved. ... have to offer it at such a high cost that ... afford it. Dr. Parsa Zadeh , founder ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 Roche ... received 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) ... severe sepsis or septic shock. With this clearance, Roche ... provide a fully integrated solution for sepsis risk assessment ... associated with bacterial infection and PCT levels in blood ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
Breaking Medicine Technology: