Navigation Links
UTMB study identifies women at higher risk of significant bone loss on injectable birth control
Date:12/21/2009

GALVESTON, Texas Nearly half of women using depot medroxyprogesterone acetate (DMPA), commonly known as the birth control shot, will experience high bone mineral density (BMD) loss in the hip or lower spine within two years of beginning the contraceptive, according to researchers at the University of Texas Medical Branch at Galveston.

The study, reported in the January 2010 issue of Obstetrics and Gynecology, was the first to show that women on DMPA who smoke, have low levels of calcium intake and never gave birth are at the highest risk for BMD loss. The researchers also found that high risk women continued to experience significant losses in BMD during the third year of DMPA use, especially in the hip the most common facture site in elderly women.

DMPA is an injected contraceptive administered to patients every three months. According to the American College of Obstetricians and Gynecologists, more than two million American women use DMPA, including approximately 400,000 teens. DMPA is relatively inexpensive compared with some other forms of birth control, has a low failure rate and doesn't need to be administered daily, which contributes to the contraceptive's popularity.

"Bone mineral density loss is not a significant concern for all women who choose DMPA," says senior author Dr. Abbey Berenson, professor in the department of obstetrics and gynecology and director of the Center for Interdisciplinary Research in Women's Health at UTMB.

According to Berenson, over the last several years there's been a fair amount of confusion about how to counsel patients. "Based on these findings, clinicians have the information they need to recommend basic behavior changes for high risk women to minimize BMD loss," she said.

The study followed 95 DMPA users for two years. In that time, 45 women had at least five percent BMD loss in the lower back or hip. A total of 50 women had less than five percent bone loss at both sites during the same period.

By and large, BMD loss was higher in women who were current smokers, had never given birth and had a daily calcium intake of 600 mg or less far below the recommended amounts. Moreover, BMD loss substantially increased among the women with all three risk factors. Age, race or ethnicity, previous contraceptive use and body mass index were not associated with higher BMD loss.

The researchers followed 27 of the women for an additional year and found that those who experienced significant BMD loss in the first two years continued to lose bone mass.

"These losses, especially among women using DMPA for many years, are likely to take an extended period of time to reverse," says first author Dr. Mahburbur Rahman, assistant professor in the department of obstetrics and gynecology and Center for Interdisciplinary Research in Women's Health.

The researchers note that while this study will help physicians counsel women with modifiable risk factors who wish to use DMPA, prevention of bone loss while using the contraceptive and reversibility of BMD loss are still not well understood and further research is needed.


'/>"/>

Contact: Kristen Hensley
409-772-6397
University of Texas Medical Branch at Galveston
Source:Eurekalert

Related medicine news :

1. With Cardiac Rehab, More Is Better: Study
2. Study shows health care spending spurs economic growth
3. New study explores role of sexual, social behaviors in seniors well-being
4. Sex in university may be better for mature audiences: study
5. Cardiome Announces Investigational Candidate, Vernakalant, Meets Primary Endpoint in European Comparator Study
6. New Study Shows No Medicare Savings if Congress Moves Against Physician Owned Hospitals.
7. NIH awards La Jolla Institute $18.8 million for major infectious disease study
8. U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines
9. New study links DHA type of omega-3 to better nervous-system function
10. New Study Reveals Pistachios Have Anti-Inflammatory Properties
11. Sleep Study Shows Pillo1 Re-Educates Body to Naturally Move Into Optimal Sleep Position and Increases REM Sleep by 21.3%
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/31/2016)... ... May 31, 2016 , ... To meet a ... the healthcare industry, The University of Scranton is adding a Certificate in Health ... a career in rapidly growing field of healthcare information. , Healthcare organizations ...
(Date:5/31/2016)... Washington, NY (PRWEB) , ... May 31, 2016 , ... ... other essential nutrients to on the go individuals and dedicated athletes, continues to transform ... , Loaded with whey, pea and milk protein, branched-chain amino acids (BCAA), alkaline ...
(Date:5/30/2016)... ... May 30, 2016 , ... "This ... FCPX," said Christina Austin - CEO of Pixel Film Studios. , TransPack ... Cut Pro X. Choose from abstract transitions to more simple wipes with blur ...
(Date:5/30/2016)... ... May 30, 2016 , ... ... while Shaolin warrior 8-day-8 and 8-night special intensive summer training camp starts on ... overnight summer camp offers families and children a fun and unique experience with ...
(Date:5/29/2016)... , ... May 29, 2016 , ... Whole Health Supply ... clipper that has been available via Amazon.com. This new style of nail clipper ... , The jaw opening is approximately 4mm and the actual handle is 2.5mm thick ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... Israel , May 31, 2016 ... its proprietary plant-based rhCollagen technology for tissue repair products ... Chief Scientist of Israel,s Ministry ... 12 million development project for 2016. The Chief Scientist,s grant ... year,s authorized grant, which totaled NIS 4.7 million.  ...
(Date:5/31/2016)... LONDON , May 31, 2016 ... der World Health Assembly zur Eliminierung von viraler ... 194 Mitgliedsstaaten eine historische Verpflichtung eingegangen, virale Hepatitis ... 69 . World Health Assembly haben sich ... Strategie bzgl. viraler Hepatitis (Global Viral Hepatitis Strategy) ...
(Date:5/30/2016)... Transparency Market Research has published ... Market - Global Industry Analysis, Size, Share, Growth, Trends, ... the global advanced (3D/4D) visualization systems market was valued ... to expand at a CAGR of 6.4% from 2016 ... Advanced (3D/4D) visualization systems have propelled the ...
Breaking Medicine Technology: