Navigation Links
UTHealth study: Stem cells may provide treatment for brain injuries
Date:3/10/2011

HOUSTON (March 10, 2011) Stem cells derived from a patient's own bone marrow were safely used in pediatric patients with traumatic brain injury (TBI), according to results of a Phase I clinical trial at The University of Texas Health Science Center at Houston (UTHealth). The results were published in this month's issue of Neurosurgery, the journal of the Congress of Neurological Surgeons.

"Our data demonstrate that the acute harvest of bone marrow and infusion of bone marrow mononuclear cells to acutely treat severe TBI in children is safe," said Charles S. Cox, Jr., M.D., the study's lead author and professor of pediatric neurosurgery at the UTHealth Medical School. The clinical trial, which included 10 children aged 5 to 14 with severe TBI, was done in partnership with Children's Memorial Hermann Hospital, where Cox is director of the pediatric trauma program.

All the children were treated within 48 hours of their injury with their own stem cells, which were collected from their bone marrow, processed and returned to them intravenously. UTHealth's Department of Neurology is also currently testing the same bone marrow stem cell procedure in adults with acute stroke. In a separate trial, Cox is testing the safety of using a patient's own cord blood stem cells for traumatic brain injury in children.

As a Phase I trial designed to look at feasibility and safety, the study did not assess efficacy. However, after six months of follow-up, all of the children had significant improvement and seven of the 10 children had a "good outcome," meaning no or only mild disability.

Children who survive severe TBI are often left with serious complications and disability. Currently, there are no effective treatments to protect or promote repair of the brain in these brain-injured children.


'/>"/>

Contact: Deborah Mann Lake
deborah.m.lake@uth.tmc.edu
713-500-3304
University of Texas Health Science Center at Houston
Source:Eurekalert  

Page: 1

Related medicine news :

1. Helicobacter pylori infection linked to decreased iron levels in otherwise healthy children, according to research at UTHealth
2. UTHealth study suggests private insurers control health care spending better than Medicare
3. UTHealth receives $11 million NIDA grant
4. UTHealth researchers awarded $15 million for teen pregnancy prevention
5. UTHealth researcher receives grant for Alzheimers study
6. Sugary sports drinks mistakenly associated with being healthy, say UTHealth researchers
7. UTHealth School of Nursing to host conference on aging and abuse
8. UTHealth receives $15 million for health information technology research
9. UTHealth to serve as Health Information Technology Regional Extension Center
10. Study: Homeless patients cost $2,500 more than the average patient for each hospital stay
11. Study: Negative classroom environment adversely affects childrens mental health
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UTHealth study: Stem cells may provide treatment for brain injuries
(Date:4/17/2014)... as the leading weapon against the deadly disease could ... research indicating it simply needs to be administered differently. ... cheap anti-malarial drug chloroquine in treating and preventing the ... half a million people each year around the world. ... to chloroquine, but research carried out at the Australian ...
(Date:4/16/2014)... 15, 2014 The Translational Genomics Research Institute (TGen) ... Founders Dinner for their support of TGen,s research into ... March 28 in Scottsdale. , Catherine Ivy, Founder and ... TGen,s John S. McCain Leadership Award, named for U.S. ...
(Date:4/16/2014)... , DOWNERS GROVE, Ill. April 16, 2014 ... of surveillance colonoscopy in average-risk patients with one to ... about 90 percent of cases. This may be an ... multicenter endoscopic database study to quantify adherence to guidelines ...
(Date:4/15/2014)... fish caused nearly half of all injuries aboard commercial ... freezer-longliner vessels operating off the coast of Alaska, new ... those injuries and others aboard the two types of ... the research methods used in the study could help ...
(Date:4/15/2014)... the University of California, San Diego School of Medicine have ... C virus get liver disease and why the virus is ... , The hard-to-kill pathogen, which infects an estimated 200 million ... mitochondria dismantling the cell,s innate ability to fight infection. ...
Breaking Medicine News(10 mins):Health News:Scientists find new way to fight malaria drug resistance 2Health News:TGen honors Catherine Ivy and Craig Jackson with Leadership; Collaborative Spirit awards 2Health News:Surveillance colonoscopy recommendations for average-risk patients with 1 to 2 small polyps consistent with guidelines 2Health News:Surveillance colonoscopy recommendations for average-risk patients with 1 to 2 small polyps consistent with guidelines 3Health News:Changes in processing, handling could reduce commercial fishing injuries 2Health News:Breaking bad mitochondria 2
... before marriage, say an overwhelming 91 percent in an SMS ... ,The survey, conducted by manoramaonline/yuva, saw 22,578 people ... was a must before marriage. Just 2,032 said that such ... just been published. ,According to the Kerala State ...
... and less inclined to follow a career in general practice, ... of Australia.// ,Dr Catherine Joyce, Senior Lecturer in ... and co-author of the study, says places in the general ... of the past six years. ,The study compared ...
... Org" is currently touring South Africa to raise awareness of ... ,Betty Chiu, a member of this organization has ... encouraging other youngsters to follow her example and get themselves ... Org' was established three years ago at a Canadian high ...
... links exist between Alzheimer's and Type 2 diabetes, which has ... forms of the same disease. ,Researchers have found ... is similar to the effect of Alzheimer's on the brain. ... International Conference on Alzheimer's Disease and Related Disorders in Madrid, ...
... investigators from the Howard Hughes Medical Institute, have developed ... unknown genetic mutations that can trigger cancerous growth. The ... analyse the proteins instead of the genes, which are ... reduced the time it takes to target the molecular ...
... clinic has been established by two leading fertility experts, ... ages of 45 with the// treatment. ,Professor ... leading authority in the field of IVF, and Paul ... to carry out pre-implantation genetic diagnosis that is the ...
Cached Medicine News:Health News:Majority of Keralites Vote in Favor of HIV Certificate Before Marriage 2Health News:Diabetes and Alzheimer's disease May be Two Sides of the Same Coin 2Health News:New Technique Identifies Unknown Genetic Mutations That Can Cause Cancer 2Health News:New Technique Identifies Unknown Genetic Mutations That Can Cause Cancer 3Health News:Scotland's First 'Stand-Alone' Private Fertility Centre Established 2Health News:Scotland's First 'Stand-Alone' Private Fertility Centre Established 3Health News:Scotland's First 'Stand-Alone' Private Fertility Centre Established 4
(Date:1/15/2014)... , January 15, 2014 Shire plc (LSE: SHP, ... Office of Fair Trading (OFT) approval condition to the announced tender ... VPHM).   As a result of the waiver, the ... to complete the tender offer on January 24, 2014 following the ...
(Date:1/15/2014)... Fla. , Jan. 15, 2014  In an unprecedented effort to ... TB in ambulances and other transport vehicles, an advanced and portable ... rescue personnel for the first time. In order ... with these deadly pathogens, West Palm Beach ...
(Date:1/15/2014)... 2014 The Cadence Fitness & Health Center has ... Medical Fitness Association, a non-profit organization assisting medically integrated ... The Cadence Fitness & Health Center is the only ... in the Chicagoland area. "The certification means ...
Breaking Medicine Technology:Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Superbugs No Longer Ride In Rescue Vehicles 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3
... Boston Scientific Corporation (NYSE: BSX ) ... quality of life outcomes, based on one-year data from ... while the overall cost effectiveness of percutaneous coronary intervention ... according to patient characteristics, PCI was more cost effective ...
... to be presented at Israel Society of ... reach 5 months from single treatment - Data ... scores of expensive injections MISGAV, Israel and LONDON, March ... that the latest, encouraging results of the Company,s ongoing ...
Cached Medicine Technology:SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease 2SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease 3SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease 4SYNTAX Analysis Finds Treatment With TAXUS(R) Express2(TM) Stents More Cost Effective Than Bypass Surgery in Many Patients With Complex Coronary Artery Disease 5Medgenics' Phase I/II Clinical Trial Now Shows EPODURE Continuous Anemia Treatment Lasting 5 Months in Kidney Disease Patients 2Medgenics' Phase I/II Clinical Trial Now Shows EPODURE Continuous Anemia Treatment Lasting 5 Months in Kidney Disease Patients 3Medgenics' Phase I/II Clinical Trial Now Shows EPODURE Continuous Anemia Treatment Lasting 5 Months in Kidney Disease Patients 4
The Benchmark Microplate Reader, with its increased wavelength range of 340 to 750 nm and high performance optics, provides flexibility for specialized applications requiring increased linearity, ult...
Plate Reader is an eight channel photometer for the sequential and simultaneous reading of micro-plate strips with 96 wells. High technology, user friendly, powerful and reliable....
TC-98 elisa strip reader. Reads, calculates, and prints results for up to 12 wells in about 30 seconds. Single point calibration. Multi-point calibration....
Stat Fax 2200 Incubator shaker....
Medicine Products: