This approach was invented by the late John Kanzius, an entrepreneur, former radio station owner and M. D. Anderson patient who knew that radio waves, which usually pass harmlessly through the body, will cook any metal in their path. "The key to making this work is to so precisely target nanoparticles to the tumor that you destroy the tumor with radio waves while sparing other tissue," Curley said. "The CTO will address that central issue."
Nicholas Peppas, Sc.D., one of the project leaders of the grant, chair of the Department of Biomedical Engineering at UT Austin and the Fletcher Stuckey Pratt Chair in Engineering, said, "I am delighted to collaborate with my colleagues at the UT Health Science Center on this extremely important research. Our work will provide advanced forms of oral delivery of chemotherapeutic agents and will identify cellular mechanisms that will improve the administration of drugs for cancer treatment to specific sites."
Other CTO senior project leaders and faculty investigators include M. D. Anderson Cancer Center researchers: Isaiah J. Fidler, D.V.M., Ph.D., professor of the Department of Cancer Biology; Wadih Arap, M.D., Ph.D., professor of medicine and cancer biology; and Renata Pasqualini, Ph.D., professor of medicine and cancer biology. CTO researchers from Rice University include Rebecca Richards-Kortum, Ph.D., professor of bioengineering, and Lon J. Wilson, Ph.D., professor of chemistry. CTO members from the UT Health Science Center include: Vittorio Cristini, Ph.D., professor of health informatics, and Paolo Decuzzi, Ph.D., associate professor of health informatics. Representing the Harvard University/Massachusetts General Hospital is Seok-Hyun "Andy" Yun, Ph.D. , assistant professor of dermatology.
"Cancerous cells and tissues interact with light differently than healthy tissues, and our lab works to develop minimally invasive technologies that recognize these differe
|Contact: Robert Cahill|
University of Texas Health Science Center at Houston