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UT Southwestern scientists discover new pathway to potential therapies for advanced prostate cancer
Date:7/25/2011

for initiating hormone production earlier in the process.

"This now suggests that a potential drug target is one step upstream in the pathway," said Dr. Sharifi. "This can be thought of as charting a map of the correct pathway. You have to figure out which way the river flows before you can block the river."

The findings also will help researchers develop accurate biomarkers of response and resistance to hormonal therapies, which eventually will help identify why and how prostate cancer tumors become resistant, he said.


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Contact: Robin Russell
robin.russell@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

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