Navigation Links
UT Southwestern researchers investigate predictors for sickle-cell-anemia complications
Date:2/28/2008

o are at greater risk of having a stroke.

Another study by Dr. Quinn and his colleagues appeared in the January issue of the journal Blood. That study examined how effectively a model developed by the Cooperative Study of Sickle Cell Disease (CSSCD) predicted severe disease in the newborn cohort.

Because sickle cell disease can affect children in many different ways, it is difficult to identify young children who are at high risk of adverse outcomes before irreversible organ damage occurs. Such outcomes include death, stroke, frequent pain or recurrent acute chest syndrome. The CSSCD criteria, which evaluates patients based on factors such as occurrences of dactylitis a type of painful swelling of the hands and feet in the first year of life, steady-state hemoglobin concentration in the second year of life, and steady-state leukocyte count in the second year of life, was created in hopes that a predictive model would allow early, tailored therapy to prevent adverse outcomes.

We found the CSSCD model was not better than random prediction when applied to the Dallas Newborn Cohort, said Dr. Quinn, the Blood studys lead author. Most subjects who experienced adverse events were predicted to be at low risk for adverse events, and no subject who was predicted to be at high risk actually experienced an adverse outcome. We concluded that the model was not clinically useful, at least not in the Dallas cohort.

Dr. Quinn said the findings suggest that the CSSCD model should not be used as the sole criterion to initiate early, high-risk intervention and that a robust early prediction model is still needed.


'/>"/>

Contact: Erin Prather Stafford
erin.pratherstafford@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. UT Southwestern surgeons complete North Texas first single-incision gallbladder removal
2. UT Southwestern plastic surgeons deploy new carbon dioxide-based fractional laser
3. BMI criteria for obesity surgery should be lowered, UT Southwestern researchers suggest
4. UT Southwestern: Patients with mild Cushing syndrome may benefit from adrenalectomy
5. Physicians seek to improve the quality of sleep in ICU, researchers at UT Southwestern report
6. UT Southwestern urologist uses Botox to treat debilitating condition
7. UT Southwestern researcher named Howard Hughes Medical Institute investigator
8. 2 UT Southwestern researchers elected to National Academy of Sciences Institute of Medicine
9. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
10. UT Southwestern scientist receives NIH Directors New Innovator Award
11. UT Southwesterns obesity research receives $22 million NIH Roadmap grant
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UT Southwestern researchers investigate predictors for sickle-cell-anemia complications
(Date:7/31/2015)... Atlanta, GA (PRWEB) , ... July 31, 2015 ... ... the five new industry players to know in predictive health analytics , ... machine learning technologies. The firm creates predictive software that targets patient and population ...
(Date:7/31/2015)... ... July 31, 2015 , ... Jacksonville-based drug and alcohol ... North Conference Center. The medical community, social workers, law enforcement, and government officials ... aligned in the effort to better understand and combat sex trafficking. Lead by ...
(Date:7/31/2015)... CA (PRWEB) , ... July 31, 2015 , ... According to the article ... floor of the Pasadena courthouse was contained and extinguished by the city’s fire department before ... in the building at the time of the fire, and it was a fire alarm ...
(Date:7/31/2015)... Texas (PRWEB) , ... July 31, 2015 , ... As ... Sitter believes community involvement and support of animal welfare organizations is essential to the ... the third consecutive year in the National Association of Professional Pet Sitters (NAPPS) annual ...
(Date:7/31/2015)... ... 31, 2015 , ... Girl Scouts of Historic Georgia and Peach State Health ... Scout "Be a Friend First" program. Representatives from Peach State Health Plan presented a ... Health Plan and our parent company, Centene Corporation, are dedicated to raising anti-bullying awareness. ...
Breaking Medicine News(10 mins):Health News:Jvion Showcased as Leader in the Predictive Analytic Market 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 3Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 2Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 4Health News:Peach State Health Plan Presents $10,000 Check for “Be a Friend First” Anti-Bullying Program to Local Girl Scouts 2
... FRIDAY, Jan. 14 (HealthDay News) -- Exposure to bright artificial ... your sleep and may increase the risk of high blood ... included 116 healthy participants, aged 18 to 30, who were ... eight hours before bedtime for five consecutive days. Blood plasma ...
... 2011) Based on a survey of thousands of ... physician-researchers from Los Angles Biomedical Research Institute at Harbor-UCLA ... a guide to the top 1 percent of physicians ... "America,s Top Doctors," chose another 16 LA BioMed physician-researchers ...
... Ont., Jan. 13, 2011Patients who must return to dialysis ... on home dialysis as hospital dialysis, but few choose ... Perl, a nephrologist at St. Michael,s Hospital. Despite ... an increasing number of patients return to dialysis. These ...
... study by Ohio State University cancer researchers provides a ... of targeted agents, one that inhibits an overactive, cancer-causing ... that silence genes that normally prevent cancer. Both types ... in clinical trials, the researchers note. The findings, published ...
... The more you walk, the lower your risk of diabetes, ... who participated in a study to map diabetes levels across ... at the start of the study and provided details about ... given a pedometer and instructed how to use it. ...
... 2011 AIUM Annual Convention and Preconvention Program, the only ... all disciplines of medical ultrasound, to be held April ... convention program incorporates an unprecedented selection of scientific research ... a focus on emerging applications and patient safety. ...
Cached Medicine News:Health News:Bright Lights at Night May Raise Diabetes Risk 2Health News:LA BioMed researchers among 'America's Top Doctors' 2Health News:Home dialysis effective for kidney patients after transplant fails 2Health News:Study provides molecular rationale for combining targeted agents to treat breast cancer 2Health News:The More You Walk, the Lower Your Diabetes Risk: Study 2Health News:AIUM unveils original features at 2011 convention 2
(Date:7/30/2015)... , July 30, 2015 Eisai Inc. announced ... the United States , European Union and ... and MHLW, respectively) for eribulin, for the treatment of ... received prior chemotherapy for advanced or metastatic disease. ... from a pivotal global Phase 3 clinical trial (Study ...
(Date:7/30/2015)... COTTAGE, New York , July 30, 2015 /PRNewswire/ ... release of its latest report titled, "Continuous Glucose Monitoring ... - 2020". According to the report, the global continuous ... Mn in 2014 and is expected to reach US$ ... during the forecast period, 2015 to 2020. ...
(Date:7/30/2015)... , July 30, 2015  Medimetriks Pharmaceuticals, ... the second Phase III clinical study for Ozenoxacin, ... impetigo.  Medimetriks owns the exclusive U.S. rights to ... trial, conducted at 44 centers with an emphasis ... patients aged 2 months and older with a ...
Breaking Medicine Technology:Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 2Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 3Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 4Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 5Global Continuous Glucose Monitoring (CGM) Systems Market: Transmitters and Monitors Most Dominant Segment, Says Future Market Insights 2Global Continuous Glucose Monitoring (CGM) Systems Market: Transmitters and Monitors Most Dominant Segment, Says Future Market Insights 3Global Continuous Glucose Monitoring (CGM) Systems Market: Transmitters and Monitors Most Dominant Segment, Says Future Market Insights 4Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 2Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 3
... Sciences University, Augusta, GA  exhibited a poster ... Research in Los Angeles, in which their clinical study ... IV Connector significantly decreased the incidence of catheter-related ... to a simple split septum with negative displacement IV ...
... Food and Drug Administration is warning that terbutaline administered by ... in pregnant women for prevention or prolonged (beyond 48-72 hours) ... maternal heart problems and death. In addition, oral terbutaline tablets ... labor. The FDA is requiring the addition of a Boxed ...
Cached Medicine Technology:New Clinical Study Shows RyMed InVision-Plus® IV Connector Dramatically Reduced Catheter-Related Bloodstream Infections by Over 92% 2New Clinical Study Shows RyMed InVision-Plus® IV Connector Dramatically Reduced Catheter-Related Bloodstream Infections by Over 92% 3FDA Warns Against Certain Uses of Asthma Drug Terbutaline for Preterm Labor 2FDA Warns Against Certain Uses of Asthma Drug Terbutaline for Preterm Labor 3
... This upright freezer uses ultra-thin vacuum ... traditional urethane insulation, to increase storage ... Holds (336) 2" boxes or 3,336 ... preservation, reduces energy consumption and extends ...
... Simple, economical, moderate-sized CO2 incubator with ... with glass inner door, HEPA filtered ... minimize sample exposure. Simple, large character ... IR CO2 sensing and mulitple temperature ...
... By combining the corrosion resistance ... antibacterial properties of copper, SANYO offers ... sterile, long-lasting and maintenance-free. The sterile ... valid test results and the safety ...
ArcticTemp Upright Freezer -20C. Quick, even freezing. Heavy duty compressor. Deep door racks. Front gated bottom shelf. Interior light. Locks One year warranty on unit and 5 year warranty on compres...
Medicine Products: