Navigation Links
UT Southwestern researcher: Supplemental breast ultrasound boosts cancer detection
Date:5/13/2008

DALLAS May 13, 2008 Among women at high-risk of developing breast cancer, breast ultrasound combined with mammography may detect more cancers than mammography alone, according to results of a multicenter trial that included UT Southwestern Medical Center researchers.

Overall, 40 participants were diagnosed with breast cancer. Of those cases, a dozen lesions were suspicious only on ultrasound and eight were suspicious on both ultrasound and mammography.

The most recent findings, presented in the current issue of The Journal of the American Medical Association, are from the first round of screening in the American College of Radiology Imaging Networks ACRIN-6666 trial. More than 2,800 women at high risk of developing breast cancer participated. The median age of the participants was 55 years and more than half had a personal history of breast cancer.

Breast ultrasound is a noninvasive procedure that uses sound waves to make a picture of the tissues inside the breast. It has traditionally been used after mammography to evaluate possible abnormalities found at screening or on physical examination. Because of recently reported studies, breast cancer screening using ultrasound for high-risk women is beginning to gain traction.

Dr. W. Phil Evans, a study author and professor of radiology at the UT Southwestern Center for Breast Care, said ultrasound is attractive for supplemental screening because it is widely available, is well-tolerated by patients and involves no radiation. Its also less costly than magnetic resonance imaging.

However, adding a single ultrasound to mammography does increase the number of false positives, said Dr. Evans. Whether or not the risk of false positives will diminish with subsequent rounds of the screening trial remains to be seen, but its something were tracking.

The trial compared the effectiveness of using ultrasound screening and mammography with mammography alone in detecting breast cancer. Potential candidates were excluded if they had signs or symptoms of breast cancer; had recent surgical or image-guided breast procedures; or if they had undergone MRI or tomosynthesis within 12 months, or mammography or whole breast ultrasound within 11 months. Women with breast implants and those who were pregnant, lactating or planning to become pregnant within two years of study entry were also excluded.

The results come on the heels of a recommendation by the American Cancer Society that annual breast MRI be used in addition to mammography for screening women at very high risk of breast cancer. The societys guidelines dont apply to the large number of women who are considered to be at intermediate or high risk for developing breast cancer but are not eligible for MRI.


'/>"/>

Contact: Kristen Holland Shear
kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Related medicine news :

1. UT Southwestern Medical Center receives grant from the Robert Wood Johnson Foundation
2. UT Southwestern testing new hybrid hearing device combining advantages of hearing aids, implants
3. UT Southwestern researchers investigate predictors for sickle-cell-anemia complications
4. UT Southwestern surgeons complete North Texas first single-incision gallbladder removal
5. UT Southwestern plastic surgeons deploy new carbon dioxide-based fractional laser
6. BMI criteria for obesity surgery should be lowered, UT Southwestern researchers suggest
7. UT Southwestern: Patients with mild Cushing syndrome may benefit from adrenalectomy
8. Physicians seek to improve the quality of sleep in ICU, researchers at UT Southwestern report
9. UT Southwestern urologist uses Botox to treat debilitating condition
10. UT Southwestern researcher named Howard Hughes Medical Institute investigator
11. 2 UT Southwestern researchers elected to National Academy of Sciences Institute of Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... “Emotions are sacred, valid, honored, encouraged. This ... positive education company Generation Mindful. To help change the mindset of parents and educators ... skills, she created the Time-In Toolkit, which launched on Kickstarter 3 weeks ago and ...
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... Alcovit, a ... to ramp up its marketing efforts with its product now available through Jet.com. ... to the public. The effervescent powdered drink is designed to quickly detox the body ...
(Date:8/18/2017)... ... ... “Our Mountains to Climb: A Journey of Love and Faith Through Trials”: ... faith they shared to overcome struggles in life. “Our Mountains to Climb: A Journey ... Corcoran, a retired teacher and happily married since 1999; the author’s personal experiences drive ...
(Date:8/18/2017)... ... ... “Beyond Our Imaginations: The Infinite God”: shows the importance of God in living ... of published author, Mark Lawrence, born in Michigan, the author has lived in various ... greater man of God is that I have to be more mindful of feminine ...
(Date:8/18/2017)... ... ... Mandate for Kingdom Builders”: a call to walk as citizens of the Kingdom and ... published author, John F. McGeorge, Jr. Dr. John F. McGeorge Jr., B.A., J.D., ... three decades training pastors and Christian leaders. He also met his wife, Valerija, ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... , Aug. 7, 2017  Endo International plc ... reached agreements to resolve virtually all known U.S. mesh ... discussions to resolve the known remaining U.S. claims at ... payments beginning in the fourth quarter of 2017 and ... of its second quarter 2017 results, the Company intends ...
(Date:8/4/2017)... Aug. 3, 2017  Agragen, LLC, a ... in the biopharmaceutical, nutraceutical, and aquacultural feed sectors, ... its lead drug candidates, AGR131.  This drug is ... from the blood of patients suffering from inflammatory ... bowel disease. ...
(Date:8/2/2017)... Aug. 2, 2017 Fenita J. ... as a Pinnacle Lifetime Professional in the Field ... Manager at Turing Pharmaceuticals, AG. Her skills and ... relationship building.                ... 25 years of experience as a highly successful ...
Breaking Medicine Technology: