Navigation Links
UT Southwestern research team's anti-malarial work wins international Project of the Year award
Date:6/6/2011

osals to the organization and, if the investigative plan is accepted, their team receives funding and scientific advisory support.

"The project led by Meg Phillips quickly became a firm favorite for MMV's Project of the Year 2010," said Tim Wells, chief scientific officer for MMV. "It was impressive not only for its progress in bringing inhibitors forward for clinical testing but also for the way in which the independent international team worked together."

So far, the lead compound has been shown to kill the malaria parasite in mouse models. Further tests to demonstrate safety are needed before the compound could be developed into a drug for clinical trials, Dr. Phillips said. Besides support from MMV, a five-year grant from the National Institutes of Health is funding this research.

"We were trying to find a compound that would bind the parasite enzyme selectively and stop its function without inhibiting the human enzyme. Therefore, the parasites can't make key building blocks for DNA and RNA biosynthesis and they die," said Dr. Phillips.

Dr. Phillips and three other team members received their awards at MMV's annual board and stakeholders meeting in Tanzania. United Republic of Tanzania President Jakaya Mrisho Kikwete presented the awards. MMV holds its meeting each year in an area affected by malaria.

Having done graduate work on African sleeping sickness, another parasitic disease, Dr. Phillips was drawn to research on malaria drug development soon after joining the UT Southwestern faculty in 1992. Although the odds of discovering an approved anti-malarial drug are slim only about one in 10 compounds at this stage of development make it to market Dr. Phillips said the potential to make a life-saving drug discovery is worth it.

"This is about as cool as it gets. If you are able to actually do research, help people and have an impact, that is just fantastic," Dr Phillips said.


'/>"/>

Contact: Debbie Bolles
debbie.bolles@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Drug can reverse overgrown hearts to help prevent heart failure, UT Southwestern researchers find
2. UT Southwesterns Luis Parada elected to National Academy of Sciences
3. Antidepressants may not improve all symptoms of depression, UT Southwestern researchers find
4. Limiting carbs, not calories, reduces liver fat faster, UT Southwestern researchers find
5. Pelvic-repair device developed by UT Southwestern surgeons enables minimally invasive trauma surgery
6. UT Southwestern pediatricians launch landmark childrens health study
7. Grant helps UT Southwestern researcher study causes of preterm birth
8. Dangerous blood pressure increases during exercise can be blocked, UT Southwestern researchers find
9. UT Southwestern research advances fight against kidney cancer
10. Annual sonograms are needed to verify correct IUD position, UT Southwestern obstetricians say
11. UT Southwestern receives $36.7 million for cancer research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... ... , ... Most employers have been using multi-tier prescription drug plans for many ... significant increase in the use of 4-tier plans, which typically cover the highest cost ... is expected to continue, according to UBA. , UBA’s survey finds that, since 2009, ...
(Date:7/28/2015)... , ... July 28, 2015 , ... ... source for identifying Top Doctors, has based its selection process on the foundation ... outstanding in their medical specialties, in any area of medicine and in any ...
(Date:7/28/2015)... ... July 28, 2015 , ... Advanced Fertility Center of ... inception in 2010, and Dr Dozortsev , a Reproductive Laboratory Director at AFCT, ... 2012, he was succeeded by Dr Gianpiero Palermo, who is credited with the discovery ...
(Date:7/28/2015)... ... July 28, 2015 , ... American ... RN to BSN cohorts for Geisinger Health System (GHS), one of the ... and associate degree prepared nurses with access to American Sentinel’s affordable, flexible and ...
(Date:7/28/2015)... ... July 28, 2015 , ... North American Seminars will present ... of 2015 . These seventeen courses are pre-approved for CME credit for ... Mobility in the Older Adult , August 22, 2015 - August 23, ...
Breaking Medicine News(10 mins):Health News:Employers Use of Multi-Tier Pharmacy Benefits Continues to Rise 2Health News:Employers Use of Multi-Tier Pharmacy Benefits Continues to Rise 3Health News:Employers Use of Multi-Tier Pharmacy Benefits Continues to Rise 4Health News:Employers Use of Multi-Tier Pharmacy Benefits Continues to Rise 5Health News:Fort Myers Plastic Surgeon Recognized as One of the America’s “Top Doctors®” by Prestigious Castle Connolly Medical Ltd. for 5 Years in a Row 2Health News:Fort Myers Plastic Surgeon Recognized as One of the America’s “Top Doctors®” by Prestigious Castle Connolly Medical Ltd. for 5 Years in a Row 3Health News:Advanced Fertility Center of Texas Is Proud to Announce That Our Lab Director Has Been Re-elected as The American College of Embryology President 2Health News:American Sentinel University Selected to Provide Online RN to BSN Cohorts to Geisinger Health System 2Health News:American Sentinel University Selected to Provide Online RN to BSN Cohorts to Geisinger Health System 3Health News:American Sentinel University Selected to Provide Online RN to BSN Cohorts to Geisinger Health System 4Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 2Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 3Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 4Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 5Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 6Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 7Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 8
... sales forces shrinking,across the pharmaceutical industry and physicians ... a place on hospital formularies has never been,more ... on,specialized training classes to help their reps better ... to recent,research from pharmaceutical benchmarking leader Best Practices, ...
... recent survey of 202 neonatologists and pediatricians, which examined ... health needs of preterm infants, revealed that most respondents ... not place enough emphasis on or dedicate enough resources ... by MedImmune, Inc. , The incidence of preterm birth, ...
... Feb. 19 Athletes for Life,Foundation (a District of ... ) have just completed their second mobile health screening ... largest such event in the,world, at its 35th anniversary., ... area donated,their time to care for the patients, conducting ...
... Transitionz Wellness,Boutique is a one-stop-shop for anyone, male ... survivor, is going through cancer treatments, or who ... and we are pleased to announce our Grand,Opening. ... services,including wigs, hats, turbans and scarves; breast forms, ...
... the brains of patients with schizophrenia also tend to ... the Silvio Conte Center for the Neuroscience of Mental ... Louis. Shape abnormalities were found in the brain,s thalamus. ... patients with schizophrenia and their non-affected siblings and compared ...
... in neurodevelopment may have yielded up a key secret. , ... says they have determined how events at the very tips ... back in the cell,s distant nucleus. , The study also ... that influence gene activity -- working outside the cell,s nucleus. ...
Cached Medicine News:Health News:Building an Effective Sales Force to Serve the U.S. Hospital Market 2Health News:Neonatologists and pediatricians highlight progress and barriers to preemie care 2Health News:Neonatologists and pediatricians highlight progress and barriers to preemie care 3Health News:Signalife & Athletes Foundation Complete Second Mobile Health Screening 2Health News:Signalife & Athletes Foundation Complete Second Mobile Health Screening 3Health News:Transitionz Wellness Boutique Launches with Grand Opening Discounts 2Health News:Siblings of schizophrenia patients display subtle shape abnormalities in brain 2Health News:Scientists shed light on long-distance signaling in developing neurons 2Health News:Scientists shed light on long-distance signaling in developing neurons 3
(Date:7/28/2015)... , July 28, 2015  ULURU Inc. (OTCQB: ULUR) ... Stockholders and the appointment of Bradley J. Sacks ... Company,s Board of Directors has determined that the 2015 Annual ... 25, 2015 at 10:00 a.m., Central Daylight Time at the ... TX 75001. In accordance with the ...
(Date:7/28/2015)... 2015  Cepheid (Nasdaq: CPHD ) today ... clinical molecular diagnostic system designed to meet the ... just 9 inches tall, and weighing just 2.2 ... high quality PCR-based Xpert® cartridges as Cepheid,s existing ... molecular diagnostic tests to be performed in any ...
(Date:7/28/2015)... , July 20, 2015 ... addition of the "Global Post-traumatic Stress Disorder Therapeutics ... The global PTSD therapeutics market to grow at a ... This report covers the present scenario and the growth ... period 2015-2019. To calculate the market size, the report ...
Breaking Medicine Technology:ULURU Inc. Announces The Schedule For The 2015 Annual Meeting Of Stockholders And The Appointment Of Bradley J. Sacks To The Board Of Directors 2ULURU Inc. Announces The Schedule For The 2015 Annual Meeting Of Stockholders And The Appointment Of Bradley J. Sacks To The Board Of Directors 3World's First "Go-Anywhere" Molecular Diagnostic System Unveiled at AACC 2World's First "Go-Anywhere" Molecular Diagnostic System Unveiled at AACC 3World's First "Go-Anywhere" Molecular Diagnostic System Unveiled at AACC 4Global Post-traumatic Stress Disorder Therapeutics Market 2015-2019 - Growing Number of Accidents and Violence Worldwide Drives the Market 2
... 10, 2012 /PRNewswire-Asia/ -- QIAGEN (NASDAQ: QGEN ; ... its therascreen ® EGFR Mutation Detection Kit ... been shown to play an important role in certain cancers ... The approval is a milestone in QIAGEN,s Personalized ...
... 2012  Hanger Orthopedic Group, Inc. (NYSE: HGR ) ... operations for the quarter ended December 31, 2011, on Thursday, ... a press release announcing the results for the quarter ended ... Wednesday, February 8, 2012 after the close of the market. ...
Cached Medicine Technology:QIAGEN Receives Regulatory Approval in Japan for EGFR Companion Diagnostic to Guide Cancer Treatments 2QIAGEN Receives Regulatory Approval in Japan for EGFR Companion Diagnostic to Guide Cancer Treatments 3QIAGEN Receives Regulatory Approval in Japan for EGFR Companion Diagnostic to Guide Cancer Treatments 4Hanger Orthopedic Group, Inc. Announces Fourth Quarter 2011 Earnings Release Conference Call 2
Open blade speculum designed for both temporal and superior approach ocular surgery. Thumb screw adjusting mechanism. Manufactured in titanium....
Adjustable lid speculum angled 45 degrees with 17 mm curved solid blades and aspiration ports to remove excess fluid from around the eye during ocular procedures....
Open 15 mm blades allow intraocular manipulation without metal to metal contact. 16 mm lifting wings. Dull finish....
Angled for temporal approach. Solid 14 mm blades. Dull finish....
Medicine Products: