Navigation Links
UT Southwestern research team's anti-malarial work wins international Project of the Year award
Date:6/6/2011

osals to the organization and, if the investigative plan is accepted, their team receives funding and scientific advisory support.

"The project led by Meg Phillips quickly became a firm favorite for MMV's Project of the Year 2010," said Tim Wells, chief scientific officer for MMV. "It was impressive not only for its progress in bringing inhibitors forward for clinical testing but also for the way in which the independent international team worked together."

So far, the lead compound has been shown to kill the malaria parasite in mouse models. Further tests to demonstrate safety are needed before the compound could be developed into a drug for clinical trials, Dr. Phillips said. Besides support from MMV, a five-year grant from the National Institutes of Health is funding this research.

"We were trying to find a compound that would bind the parasite enzyme selectively and stop its function without inhibiting the human enzyme. Therefore, the parasites can't make key building blocks for DNA and RNA biosynthesis and they die," said Dr. Phillips.

Dr. Phillips and three other team members received their awards at MMV's annual board and stakeholders meeting in Tanzania. United Republic of Tanzania President Jakaya Mrisho Kikwete presented the awards. MMV holds its meeting each year in an area affected by malaria.

Having done graduate work on African sleeping sickness, another parasitic disease, Dr. Phillips was drawn to research on malaria drug development soon after joining the UT Southwestern faculty in 1992. Although the odds of discovering an approved anti-malarial drug are slim only about one in 10 compounds at this stage of development make it to market Dr. Phillips said the potential to make a life-saving drug discovery is worth it.

"This is about as cool as it gets. If you are able to actually do research, help people and have an impact, that is just fantastic," Dr Phillips said.


'/>"/>

Contact: Debbie Bolles
debbie.bolles@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Drug can reverse overgrown hearts to help prevent heart failure, UT Southwestern researchers find
2. UT Southwesterns Luis Parada elected to National Academy of Sciences
3. Antidepressants may not improve all symptoms of depression, UT Southwestern researchers find
4. Limiting carbs, not calories, reduces liver fat faster, UT Southwestern researchers find
5. Pelvic-repair device developed by UT Southwestern surgeons enables minimally invasive trauma surgery
6. UT Southwestern pediatricians launch landmark childrens health study
7. Grant helps UT Southwestern researcher study causes of preterm birth
8. Dangerous blood pressure increases during exercise can be blocked, UT Southwestern researchers find
9. UT Southwestern research advances fight against kidney cancer
10. Annual sonograms are needed to verify correct IUD position, UT Southwestern obstetricians say
11. UT Southwestern receives $36.7 million for cancer research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... , A mathematical model developed by NIH grantees predicts ... to prevent HIV infection via vaginal sex, whereas just ... infection via anal sex. This finding helps explain why ... PrEP, in women failed to show efficacy. Participants in ... of Truvada and tenofovir (another antiretroviral) for HIV prevention ...
(Date:10/30/2014)... 30, 2014 Graphics, coding, typography and ... with the craft of web design and require thorough ... a simpler solution to create a website can be ... contact information, customer reviews and Facebook posts all accumulate ... is the next evolution of how a business can ...
(Date:10/30/2014)... Portland, OR (PRWEB) October 30, 2014 ... law firm Hodgkinson Street LLC announces new branding ... Hodgkinson Street Mepham . After David Mepham’s promotion ... revitalizes their brand and website to include Mepham’s name ... leading medical malpractice and mediation firm, the decision to ...
(Date:10/30/2014)... Radio listeners who indicate use of four ... of traditional radio commercials and have overwhelmingly endorsed custom ... a purchasing decision. , Those are some highlights from ... radio marketing company CRN International. The research is now ... respondents who indicated they have purchased or considered purchase ...
(Date:10/30/2014)... Dennis Thompson HealthDay Reporter ... Ebola outbreak in Liberia -- one of three West African ... Health Organization officials said Wednesday. Dr. Bruce Aylward, WHO,s ... number of burials in Liberia and no increase in laboratory-confirmed ... push to tame the epidemic may be making some progress, ...
Breaking Medicine News(10 mins):Health News:Model by NIH grantees explains why HIV prevention dosing differs by sex 2Health News:Facebook Websites In Thirty-Seconds 2Health News:Hodgkinson Street Mepham Rebrands 2Health News:CRN Research On Radio Messaging Effectiveness Now Available In Four Specific Product Categories 2Health News:CRN Research On Radio Messaging Effectiveness Now Available In Four Specific Product Categories 3Health News:Ebola Outbreak in Liberia May Be Slowing: WHO 2Health News:Ebola Outbreak in Liberia May Be Slowing: WHO 3
... Tripura Medical College Sunday here to become the ... region. ,"Tripura Medical College, promoted by ... state government, is the first public private partnership ... said K. Balachandran Nair, chairman-cum-managing director, Universal Empire ...
... Quebec coroner Jacques Ramsay has recommended that Canadians suffering ... (epinephrine) or the Twinject, which// provides a double dose ... deadly situations. He has also called for ... to the patients. ,The recommendations follow the ...
... H5N1 virus in a small duck farm in the southern ... ,An animal health official from Thach Phu district, Ben Tre ... had the H5N1 virus." All 84 ducks on the ... 14 nearby farms tested negative for the virus. ...
... 22 organizations have joined hands, formalizing their consent to ... in the working environment. ,Teaming up ... has been conducting workshops for the companies that believe ... of the national business council is also on the ...
... British Heart Foundation (BHF) suggested that people with advanced heart ... their real age.// ,In ... tissues from heart bypass and transplant patients to study how ... the artery cells divide seven to 13 times more rapidly ...
... University, English cider apples have high levels of phenolics – ... ,Thus, a pint of cider is as effective ... to test cider’s effects by getting 12 volunteers to drink ... of cider in a controlled environment and avoid antioxidants in ...
Cached Medicine News:
(Date:10/31/2014)... -- Migranade, Inc. announced today the new migraine medication, ... million U.S. migraine sufferers November, 2014. The medicine is ... cause of migraines and not just the symptoms. While ... Migranade is assured to be a game changer in ... at http://www.migranade.com and will soon hit the ...
(Date:10/31/2014)... , Oct. 31, 2014  Isis Pharmaceuticals, Inc. (NASDAQ: ...  What: , Isis Pharmaceuticals, Third Quarter 2014 ... November 7 at 11:30 a.m. ET / 8:30 a.m. ... on the Internet. Simply log onto our website listed ... live event, a replay of the webcast will be ...
(Date:10/30/2014)... CHARLOTTETOWN , Oct. 30, 2014 /CNW/ - Atlantic ... three-year agreement reached between Canada,s ... Jim Keon , President of the Canadian Generic Pharmaceutical ... made the comments while speaking at the Atlantic Summit ... Charlottetown , which is being hosted by the ...
Breaking Medicine Technology:Game Changing Migraine Medication To Be Available November 2014 2Webcast Alert: Isis Pharmaceuticals' Third Quarter 2014 Financial Results Conference Call 2Webcast Alert: Isis Pharmaceuticals' Third Quarter 2014 Financial Results Conference Call 3Atlantic Canadians to Save $560-Million Through Unprecedented Three-Year Pan-Canadian Agreement on Generic Prescription Medicines 2Atlantic Canadians to Save $560-Million Through Unprecedented Three-Year Pan-Canadian Agreement on Generic Prescription Medicines 3
... Texas, Sept. 29 Luminex Corporation (Nasdaq: ... 2010 Prix Galien USA Award for its innovative xTAG® ... named Best Medical Technology at the Prix Galien USA ... 2010, at the American Museum of Natural History in ...
... asked today to make protecting the eyes from ... by increasing the prevalence of UV and eye-health ... as the Surgeon General, and in upcoming healthcare ... the Congressional Vision Caucus, provided the opening remarks ...
Cached Medicine Technology:Luminex Corporation Wins Prestigious 2010 Prix Galien USA Award 2Prevent Blindness America Issues Call-to-Action to Make UV Eye Protection a National Health Priority 2Prevent Blindness America Issues Call-to-Action to Make UV Eye Protection a National Health Priority 3
... excellent illumination (150'000 to approx. 600'000 ... length of the slit image either ... to 8 mm respectively 1 to ... allowing hairline settings providing unique depth ...
... The AQT-10 is the ultimate in clinical ... to detect the subtle red/green or blue/yellow ... as retinal toxicity (that from Plaquenil, for ... and macular degeneration. Additionally it is fast ...
... The UTAS-E 3000 is the most ... rapid and accurate measurements of retinal ... comprehensive, easy-to-use software available drives this ... such as adjustable contrast pattern stimulation, ...
... VEP technology is designed for productivity and ease ... with doctors from the University of Wisconsin who ... decade on over 5,000 subjects. All of the ... and stored, or can be preset and loaded ...
Medicine Products: