Navigation Links
UT Southwestern research team's anti-malarial work wins international Project of the Year award
Date:6/6/2011

DALLAS June 7, 2011 The discovery of a potential new anti-malarial drug by a UT Southwestern Medical Center-led research team has been awarded Project of the Year by Medicines for Malaria Venture (MMV).

The team's research, which began in 2002 under the direction of Dr. Margaret Phillips, identified a promising inhibitor of a specific enzyme that the malaria parasite requires for survival. The lead compound, uncovered during high-throughput tests at the UT Southwestern core screening laboratory and now in preclinical trials, could be ready for human studies next year.

"The problem is staying ahead of the parasite's continuing ability to develop drug resistance. If we don't discover new drugs, the parasite is going to win," said Dr. Phillips, professor of pharmacology at UT Southwestern and project leader for the drug development team that includes researchers from the University of Washington, Seattle; Monash University in Melbourne, Australia; and pharmaceutical company GlaxoSmithKline.

Each year, malaria kills 1 million to 2 million people, most of them women and children. The mosquito-transmitted disease is prevalent in Africa, South America and Asia, but virtually nonexistent in the U.S. No vaccine prevents malaria, although drugs are available to treat the infectious disease.

"If this drug succeeds, it could very well revolutionize the way malaria is treated," said Dr. David Mangelsdorf, chairman of pharmacology and a Howard Hughes Medical Institute investigator at UT Southwestern.

Of 26 projects that span the drug development pipeline from early-phase discovery work to compounds in clinical development, MMV chose the work of Dr. Phillips' team for Project of the Year based on its progress toward discovering a new anti-malarial drug.

MMV is a not-for-profit public/private partnership based in Geneva whose mission is to develop and bring affordable anti-malarial drugs to market. Researchers submit prop
'/>"/>

Contact: Debbie Bolles
debbie.bolles@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Drug can reverse overgrown hearts to help prevent heart failure, UT Southwestern researchers find
2. UT Southwesterns Luis Parada elected to National Academy of Sciences
3. Antidepressants may not improve all symptoms of depression, UT Southwestern researchers find
4. Limiting carbs, not calories, reduces liver fat faster, UT Southwestern researchers find
5. Pelvic-repair device developed by UT Southwestern surgeons enables minimally invasive trauma surgery
6. UT Southwestern pediatricians launch landmark childrens health study
7. Grant helps UT Southwestern researcher study causes of preterm birth
8. Dangerous blood pressure increases during exercise can be blocked, UT Southwestern researchers find
9. UT Southwestern research advances fight against kidney cancer
10. Annual sonograms are needed to verify correct IUD position, UT Southwestern obstetricians say
11. UT Southwestern receives $36.7 million for cancer research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2013)... IBISWorld estimates that revenue for the ... rate of 28.7% to $1.0 billion in the five years ... and 2008, no new cell therapy products were introduced, according ... during that period. In the years since, however, the Food ... factor contributed to the industry's fast growth during the five ...
(Date:5/25/2013)... Virginia (PRWEB) May 25, 2013 Superior ... that relieves pain in seconds for arthritis, tendinitis and ... in alternative pain relief products announced a magnetic ... The magnetic bracelet for pain relief is demonstrated at ... pain uses 5400 Gauss magnets and has customers often ...
(Date:5/25/2013)... AdvantaClean of Pikes Peak recently opened and ... healthy home and business in Colorado Springs and surrounding ... inspections, mold testing, mold removal , air ... , With over 120 offices nationwide, AdvantaClean is a ... full suite of services for commercial, institutional, and governmental ...
(Date:5/24/2013)... myMEDholiday.com, a popular medical tourism portal which includes an ... travel destinations in Asia, has added a helpful and ... safe and successful trip for anyone planning a healthcare ... cost-savings, how to find the appropriate doctors and facilities, ... essential advice. , A top-level marketing representative at the ...
(Date:5/24/2013)... Atlanta, GA (PRWEB) May 24, 2013 Before you ... a cup of coffee with Kathie Lee Gifford and Hoda Kotb ... http://www.digitwirl.com , will show cool tech ideas to Kathie Lee and ... Kyodo America honors our brave men and women in the military ... get ready for the BBQ, spend time with friends and family ...
Breaking Medicine News(10 mins):Health News:Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld 2Health News:Slow Healing: Cell Therapy in the US Industry Market Research Report Now Available from IBISWorld 3Health News:Magnetic bracelet relieves pain in seconds announces Superior Magnetics 2Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 2Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 3Health News:Grand Opening! AdvantaClean of Pikes Peak is Proud to Announce Water Damage Restoration, Mold Removal and Air Duct Cleaning Services to the Colorado Springs Area 4Health News:myMEDholiday.com Introduces International Patient Guide to Assist People Planning Treatment Abroad 2Health News:LawnBott® Visits the Today Show with Kathie Lee and Hoda 2
... the time in emergency rooms , , TUESDAY, Dec. 18 (HealthDay ... someone is having a heart attack, they are mistaken 9.2 ... that minutes matter with these patients and doctors have to ... say researchers from the Minneapolis Heart Institute Foundation. , "Our ...
... three and older in the United States would carry ... the 2008 University of Louisville Grawemeyer Award in Education. ... nations young children, fill a gap for working families, ... boost the economy, award winners Edward Zigler, Walter Gilliam ...
... led by Mayo Clinic have designed a technique that uses ... cells that spread from primary tumors to other parts of ... shows that this technology could be the basis for a ... appeared in the Dec. 9 online issue of Nature Medicine. ...
... inexpensive infection control measures, hospitals around the world could prevent ... TB), according to a new study in The Lancet by ... Wings for its ability to spread and kill rapidly, XDR ... identified in all regions of the world, including the United ...
... for patients with spinal cord injuries can stimulate ... compensatory changes in the brain, say Canadian researchers. ... function and the ability to walk. , A ... the remarkable benefits of rehabilitation training after a ...
... remains America,s No. 1 killer, AHA says , , TUESDAY, ... death rates in the United States are declining, the ... the nation, according to the American Heart Association. , ... for many people, according to the American Heart Association,s ...
Cached Medicine News:Health News:Diagnosis of Heart Attack Can Be Wrong 2Health News:Researchers train the immune system to deliver virus that destroys cancer in lab models 2Health News:Researchers train the immune system to deliver virus that destroys cancer in lab models 3Health News:Simple strategy could prevent half of deadly tuberculosis infections 2Health News:Intensive training post-spinal cord injury can stimulate repair in brain and spinal cord 2Health News:U.S. Heart Disease Death Rates Falling 2Health News:U.S. Heart Disease Death Rates Falling 3
(Date:5/23/2013)... JERUSALEM , May 23, 2013  Hadasit Bio-Holdings ... portfolio of biotech companies, based on intellectual property ... Israel ,s foremost medical research center, ... Neurosciences Ltd., received significant funding from the Israeli ... Chief Scientist (OCS) to support product development and ...
(Date:5/23/2013)... -- Texas, premier physician associations today announced the establishment of ... need to provide demonstrably better and more efficient patient ... "I am confident the Physician Services Organization for ... Stephen L. Brotherton , MD, president of the ... doctors are determined to make health care better and ...
(Date:5/23/2013)... , May 23, 2013  Net Medical Xpress ... telemedicine market, announced today the company has signed a ... staffing company based in Huntsville, AL ... specializes in the staffing and recruitment of telemedicine physicians. ... of the final agreement, which is expected by June ...
Breaking Medicine Technology:Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 2Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 3
... , , , , WALTHAM, Mass., Dec. ... and advisory firms for pharmaceutical and healthcare issues, finds that ... efficacy and side-effect profile, are cited most frequently by surveyed ... non-small-cell lung cancer treatment in Germany, France, Italy, Spain and ...
... HUNTINGTON BEACH, California and AMSTERDAM, December 17 ,Agendia, a ... US Food and Drug Administration (FDA) cleared its MammaPrint ... only FDA-cleared,breast cancer recurrence test available to patients and ... four clearances for MammaPrint, covering,all aspects of this important ...
Cached Medicine Technology:Surveyed European Oncologists Cite Cost Most Frequently as the Factor Preventing Their Use of Avastin for Non-Small-Cell Lung Cancer 2Surveyed European Oncologists Cite Cost Most Frequently as the Factor Preventing Their Use of Avastin for Non-Small-Cell Lung Cancer 3FDA Broadens Clearance for Agendia's MammaPrint(R) 2
Circular Spine Retractor System for microsurgical interventions in the lumbar and cervical spine region....
... also known as BMP-7, is a member of ... Bone Morphogenetic Proteins. OP-1 Implant is known to ... mature skeletal systems. The FDA approved OP-1 Implant ... 2001. OP-1 Implant is now available across the ...
... Connect allografts are dense ... anterior cortical face providing structural ... for rapid healing. These allografts ... Non-Lordotic designs. Connect allografts are ...
... maxillo-facial and cranial surgery are characterized by ... for the most varied of applications. Tailor-made ... that the system is easy to implement ... from titanium. Specially designed instruments for drilling, ...
Medicine Products: