Navigation Links
UT Southwestern receives continued NIH funding for Inner City Asthma Consortium

DALLAS Nov. 23, 2009 UT Southwestern Medical Center is among 10 institutions selected by the National Institutes of Health to share $56 million over five years as part of the Inner City Asthma Consortium (ICAC).

The ICAC, which receives funding through the NIH's National Institute of Allergy and Infectious Diseases, investigates novel treatments and causes of asthma in urban children.

Dr. Rebecca Gruchalla, chief of allergy and immunology at UT Southwestern, said continued funding of the consortium is imperative because morbidity and mortality continues to be highest in inner-city children and adolescents with asthma. Dr. Gruchalla has led the Dallas arm of the ICAC for seven years.

"The proposed studies undertaken through our continued role in the ICAC are novel, innovative and likely to help us truly make a difference in the lives of inner-city children suffering from this often debilitating disease," Dr. Gruchalla said.

Ongoing studies include a prospective, longitudinal evaluation of environmental factors that influence the development of the immune system and asthma, as well as clinical trials of possible treatment therapies.

Previous ICAC-funded research has found that:

  • A coordinated, guidelines-based approach to asthma management quickly controls asthma among inner-city adolescents.
  • Adding exhaled nitric oxide to guidelines-based care does not improve clinical outcomes.
  • Screening tests used to predict asthma activity in some patients may have little tracking success when applied to people with persistent disease who are adhering to their health care regimens.

With continued NIH funding, Dr. Michelle Gill, assistant professor of pediatrics at UT Southwestern, is leading key mechanistic studies that explore how anti-IgE therapy can decrease viral-induced seasonal asthma exacerbations. IgE antibodies are the fuel in the immune system that perpetuates asthmatic reactions and can make asthma worse in people who are sensitive to particular allergens.

"The goal of our mechanistic studies is to define how allergens interfere with immune responses to respiratory viruses. We will also investigate whether anti-IgE therapy improves these responses to seasonal viral infections in patients with asthma," Dr. Gill said.

The consortium is administered by the University of Wisconsin-Madison. In addition to UT Southwestern, research is being conducted at Boston University School of Medicine; Children's Memorial Hospital in Chicago; George Washington University School of Medicine and Health Sciences in Washington, D.C.; National Jewish Health in Denver; Johns Hopkins University School of Medicine; University of California, San Francisco; Columbia University College of Physicians and Surgeons in New York City; and the Henry Ford Hospital in Detroit.


Contact: Erin Prather Stafford
UT Southwestern Medical Center

Related medicine news :

1. Director of UT Southwestern center honored with first international neurology medal
2. UT Southwestern Responds to VA Announcement
3. UT Southwestern physicians bust myths about insulin
4. UT Southwestern researchers launch study into search-and-destroy antigen for deadly skin cancer
5. Dysport proves safe, effective anti-wrinkle treatment, UT Southwestern plastic surgeons find
6. Higher drug doses needed to defeat tuberculosis, UT Southwestern researchers report
7. UT Southwestern, UT Arlington to develop magnetic surgery tools
8. UT Southwestern researcher named HHMI Early Career Physician-Scientist
9. Former Gov. Bill Clements Makes Historic Gift to UT Southwestern With $100 Million Transformative Contribution
10. UT Southwesterns Olson wins prestigious French award for heart research
11. Participants in antidepressant drug trials are atypical patients, UT Southwestern researchers report
Post Your Comments:
Related Image:
UT Southwestern receives continued NIH funding for Inner City Asthma Consortium
(Date:10/13/2017)... ... October 13, 2017 , ... ... Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical ... the primary prevention of cardiovascular diseases during the 15th Annual Women’s Health ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Many families ... However, many long-term care insurance companies have a waiver for care if the client ... elimination period, when the family pays for care, is often waived, so the benefits ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Global Healthcare ... scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare ... activity. The fun run is geared towards children of all ages; it is ...
(Date:10/13/2017)... Fairfax, VA (PRWEB) , ... October 13, 2017 ... ... provider of DevOps and Agile Software Development, has been awarded a contract by ... (EATS) Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile ...
(Date:10/12/2017)... Del. (PRWEB) , ... October 12, 2017 , ... ... and advisory services for healthcare compliance program management, will showcase a range of ... National Association for Assisted Living (NCAL) Convention and Expo to be held October ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... --  Divoti USA will engrave and process all ... the latest FDA requirements, which stipulates new criteria regarding medical device ... of Medical ID jewelry such as Medical ID Bracelets, can rest ... terms of the new FDA requirements . ... Divoti offers this dark mark fiber laser engraving ...
(Date:10/11/2017)... , Oct. 11, 2017  Hill-Rom Holdings, Inc. ... Aspen Surgical facility in Las Piedras, Puerto ... scalpels and blades. ... that the facility sustained minor structural damage, temporary loss ... Maria. Repairs have been completed, manufacturing operations have resumed, ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
Breaking Medicine Technology: