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USC research finds certain contraceptive may pose risk of Type 2 diabetes for obese women
Date:2/7/2013

Highlights of this news release:

  • Six-month study finds that progestin-releasing contraceptives show a slight negative impact on metabolic markers, raising the risk for type 2 diabetes.

  • Contraceptive implants under the skin increase the risk more than uterine implants.

  • Longer and larger studies are needed to see if metabolic changes are temporary or long-term.

LOS ANGELES A first-of-its-kind study by researchers at the Keck School of Medicine of the University of Southern California (USC) indicates that healthy, obese, reproductive-age women who use long-acting reversible contraception (LARC) containing the hormone progestin have a slightly increased risk for developing type 2 diabetes when compared to those who use non-hormonal contraception.

The research concludes that progestin-releasing LARC appears to be safe for use by such women but needs further investigation.

Nicole M. Bender, assistant professor of clinical obstetrics and gynecology at the Keck School, was the principal investigator for the study "Effects of progestin-only long-acting contraception on metabolic markers in obese women," which appeared online in the journal Contraception on Jan. 2, 2013.

"Contraceptive studies often only look at normal-weight women," said Penina Segall-Gutierrez, co-investigator of the study and an assistant professor of clinical obstetrics and gynecology and family medicine at the Keck School. "Studies such as this are necessary because, today, one-third of women in the U.S. are overweight and one-third are obese. All women, including overweight and obese women, need to have access to safe and effective contraception."

Obese women are at increased risk for pregnancy-related complications and are sometimes warned by their doctors not to use contraceptives containing estrogen, such as the pill, patch and vaginal ring.

"[Those choices] raise the risk for blood
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Contact: Leslie Ridgeway
lridgewa@usc.edu
323-442-2823
University of Southern California - Health Sciences
Source:Eurekalert

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