Navigation Links
US Parkinson's rates highest in whites, Hispanics, and Midwest, Northeast
Date:1/27/2010

The largest epidemiological study of Parkinson's disease in the United States has found that the disease is more common in the Midwest and the Northeast and is twice as likely to strike whites and Hispanics as blacks and Asians.

The study, based on data from 36 million Medicare recipients, is both the first to produce any significant information on patterns of Parkinson's disease in minorities and to show geographic clusters for the condition.

"Finding clusters in the Midwest and the Northeast is particularly exciting," says lead author Allison Wright Willis, M.D., assistant professor of neurology at Washington University School of Medicine in St. Louis. "These are the two regions of the country most involved in metal processing and agriculture, and chemicals used in these fields are the strongest potential environmental risk factors for Parkinson's disease that we've identified so far."

The results appear online in the journal Neuroepidemiology.

Parkinson's disease is a common neurodegenerative condition that causes tremor, stiffness, slowness, mood and behavioral disorders, sleep problems and other symptoms. The disease is characterized by loss of dopamine, a compound involved in communication between brain cells.

According to Willis, genetic factors explain only a small percent of cases. Environmental factors are likely more common contributors and may include prolonged exposures to herbicides and insecticides used in farming or to metals such as copper, manganese and lead.

For the new study, Willis analyzed data on more than 450,000 cases of Parkinson's disease per year over six years, 1995 and 2000-2005. Collectively, that data included information from more than 98 percent of all Americans 65 and older.

Willis found Asians and blacks developed Parkinson's disease at half the rate of whites and Hispanics.

"We are going to try to learn more about why this is the case," says Willis. "It could be that those with Asian or African ancestry have genes that help protect them from exposure to environmental factors that cause Parkinson's disease, or they may have fewer exposures to those factors."

Epidemiologists have long debated whether Parkinson's disease is more prevalent in rural or urban areas, with some studies showing higher rates in cities and some in the countryside. Willis found the condition is more common in urban areas but concluded the comparison between the two rates offered little potential for insight into the disease.

"It's always been an open question as to how to best define the terms 'urban' and 'rural,'" she says. "Urban and rural is defined in many different and relatively arbitrary ways, and we came away convinced by our results that these distinctions have little to do with what is causing the disease."

Willis and her colleagues plan further studies of how exposure to single or combined environmental factors influences disease risk.

"This was the largest descriptive epidemiological study yet to be conducted of Parkinson's disease in the United States, and it has both given us some interesting new leads for the future research and reinforced some ideas we already had," she says.


'/>"/>

Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine
Source:Eurekalert  

Related medicine news :

1. Infection contributes to the high rates of oropharyngeal cancers
2. ZIP codes and property values predict obesity rates
3. Dr. Paul Bandt Celebrates 35th Anniversary With Desert Radiologists and a History of Healthcare in Las Vegas
4. New Study Reports High Injury Rates for Hotel Workers, Even Higher Rates for Women and Nonwhites
5. Claim Filed Against the Company and Nine Other Defendants in the Haifa Magistrates Court
6. Investigational Agent Targeting Metabotropic Glutamate 2/3 Receptors Demonstrates Antipsychotic Activity in Humans, Study in Nature Medicine Finds
7. Rates of bipolar diagnosis in youth rapidly climbing, treatment patterns similar to adults
8. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
9. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
10. REACH Registry Highlights That Patients With Peripheral Arterial Disease (PAD) Suffer High Rates of Heart Attack, Stroke, Hospitalization, and Death
11. Recovery Resources Collaborates with Two Nonprofit Agencies for Children of Alcoholics Outreach Program
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
US Parkinson's rates highest in whites, Hispanics, and Midwest, Northeast
(Date:12/5/2016)... ... December 05, 2016 , ... A newly released study ... the reproducibility and accuracy of placing precordial electrodes with little cognitive effort and ... last 60 years, studies have shown that single electrode misplacement is one of ...
(Date:12/4/2016)... , ... December 03, 2016 , ... ... 4 transitions and many more tools allowing FCPX editors to create professional looking ... Film Studios. , Perfect Harmony contains a beautifully designed 3D environment for ...
(Date:12/4/2016)... ... 03, 2016 , ... Penrose Senior Care Auditors® was announced ... evening at the 26th Annual SMU Cox Dallas 100™ Awards Ceremony and Banquet ... for Entrepreneurship. Dallas 100™, co-founded by the Caruth Institute, honors the ingenuity, commitment ...
(Date:12/4/2016)... ... December 04, 2016 , ... Are You Concerned About Mold In Your ... experienced Indoor Air Quality Companies in VA, MD and DC, recently completed its application ... The new mold law in the district of Columbia is a good thing stated ...
(Date:12/2/2016)... ... ... Lori G. Cohen and Sara K. Thompson , shareholders in global law ... 21st Drug & Medical Device Litigation Conference , taking place in New York Dec. ... chairs the firm’s Pharmaceutical, Medical Device & Health Care Litigation Practice and the Trial ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Dec. 2, 2016  Eli Lilly and Company (NYSE: ... for 2017 and provide updated financial guidance for 2016 ... a conference call on that day with the investment ... guidance. The conference call will begin at ... can access a live webcast of the conference call ...
(Date:12/2/2016)... Dec. 2, 2016 CVS Health Corporation (NYSE: ... Day in New York City on Thursday, December 15, 2016, beginning at 8:00 ... team will provide an in-depth review of the company,s ... The company will also discuss 2017 earnings guidance during ... of the event will be broadcast simultaneously on the ...
(Date:12/2/2016)... 2016 Lianluo Smart Limited (Nasdaq: ... which develops, markets and sells medical devices and ... and international markets, recently attended the ... New Progress Forum, co-hosted by the Institute of ... , Guangdong Provincial People,s Hospital and Cardiology Department ...
Breaking Medicine Technology: