Navigation Links
UNC study firms up promise of potential new cervical cancer screening tool
Date:5/21/2008

CHAPEL HILL New research into the causes of cervical cancer appears to lend weight to the promise of a potential early detection method that could help prevent the disease.

According to a study involving scientists from the University of North Carolina at Chapel Hill, persistent infection with human papillomavirus (HPV) could be a useful clinical marker for increased risk of cervical cancer, the second most common cancer in women worldwide.

HPV is a sexually transmitted virus that can cause high-grade cervical lesions, increasing a womans risk of developing invasive cervical cancer.

Currently, Pap smear tests are widely used in screening programs aimed at detecting changes in the cervix before a cancer develops. However, testing for HPV infections has the potential to be more sensitive for future cervical cancer screening programs.

In the study thought to be the first of its kind and published online in the American Journal of Epidemiology scientists reviewed 41 existing studies including over 22,500 women to systemically evaluate the association between HPV persistence and high-grade lesions or cervical cancer.

Jennifer Smith, Ph.D., research assistant professor of epidemiology in the UNC School of Public Health and senior author of the paper, said: We found that a persistent HPV infection of six months to one year was consistently associated with a womans increased risk of high-grade cervical lesions or cervical cancer.

Smith is also a member of the UNC Lineberger Comprehensive Cancer Center.

There are approximately 14 high-risk types of HPV that cause invasive cervical cancer. The two most common types are 16 and 18, which have different viral genetic patterns. These virus types are responsible for about 70 percent of invasive cervical cancer and 50 percent of high-grade lesions worldwide.

The next step will be to develop a consensus definition of HPV persistence that can then usefully inform clinical practice for future cervical cancer screening programs, Smith said. Additionally, we need more information on whether the persistence of specific HPV types such as 16 or 18 is associated with relative differences in increased risk.

In the future, measuring persistence of HPV infection may optimize screening for cervical cancer by increasing sensitivity while maintaining comparable specificity to Pap smear testing, Smith said. What that means, essentially, is that we might be better able to identify potential cervical cancer cases that could otherwise go undetected.


'/>"/>

Contact: Patric Lane
patric_lane@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
Source:Eurekalert

Related medicine news :

1. Three-Year COPD Study Found No Increase in Cardiac Events With Advair(R) 500/50
2. Study presented at DDW 2008 Confirms that New Device Significantly Improves Detection of Polyps in the Colon
3. Israeli study finds obstructive sleep apnea is health factor from day 1
4. Study finds that recalled Aqua Dots did contain poisonous chemical
5. Study reveals link among childhood allergies, asthma symptoms, and early life exposure to cats
6. Study analyzed SYMBICORT in children with persistent asthma
7. New patient satisfaction study with budesonide/formoterol combination therapy
8. Study: Doctors not always sure when to treat BP in people with diabetes
9. Study concludes no racial disparities in long-term outcomes in recipients of liver transplants
10. Study: Doctors Not Always Sure When to Treat Blood Pressure in People With Diabetes
11. JAMA publication features study on depression and head and neck cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... New York, NY (PRWEB) , ... May 27, ... ... health care world, this installment is bolstered by inspiring human interest stories, courtesy ... to the developing trends and tech within the industry, from leading advocates and ...
(Date:5/26/2016)... DC (PRWEB) , ... May 26, 2016 , ... There ... National Hot Dog and Sausage Council (NHDSC) suggests that Americans prefer their dogs straight ... dogs, 63 percent say grilling is their favorite way to cook a hot dog, ...
(Date:5/26/2016)... ... May 26, 2016 , ... Connor Sports, through its ... partner for the Tamika Catchings Legacy Tour that will commemorate the Indiana ... hardwood basketball surfaces in all forms and levels of the game, Connor Sports has ...
(Date:5/26/2016)... ... May 26, 2016 , ... MadgeTech will be showcasing its ... manufactured in Warner, New Hampshire at the MadgeTech headquarters. With products sold in more ... trusted by government agencies, including NASA. , In 2012, NASA strategically set up ...
(Date:5/26/2016)... ... 2016 , ... Memorial Day Weekend marks the unofficial start of summer and ... to make sure your family and vehicle are ready to hit the road this ... 439 deaths and an additional 50,500 serious injuries from motor vehicle crashes during the ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... -- TARE (Transarterial Radio-embolization) Using Yttrium-90 ... Overall Decreased Use of Hospital Resource ... healthcare company, has today announced the publication of ... ISPOR (International Society for Pharmacoeconomics and Outcomes Research), ... yttrium-90 glass microspheres is associated with cost savings ...
(Date:5/25/2016)... PARIS , May 25,2016 ... with the near-infrared Cellvizio platform for urological and ... MKEA, OTCQX: MKEAY) inventor of Cellvizio®, the multidisciplinary ... important regulatory milestone in the US with the ... Food and Drug Administration (FDA). This new FDA ...
(Date:5/25/2016)... and GERMANTOWN, Maryland , May ... QGEN ; Frankfurt Prime Standard: QIA) today announced that ... with Therawis Diagnostics GmbH to develop and commercialize predictive assays ... market PITX2 as a marker to predict effectiveness of anthracycline ... "We are pleased to partner with Therawis, which ...
Breaking Medicine Technology: