Navigation Links
UNC study finds oral tongue cancer increasing in young, white females
Date:3/8/2011

Chapel Hill, NC A UNC study released this week in the Journal of Clinical Oncology finds an increasing incidence of squamous cell carcinoma of the oral tongue in young white females in the United States over the last three decades.

A team of researchers from UNC Lineberger Comprehensive Cancer Center analyzed data from the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) database and found that, between 1975 and 2007, the overall incidence for all ages, genders, and races of the disease was decreasing. However, the incidence of oral tongue squamous cell carcinoma rose 28 percent among individuals ages 18 to 44. Specifically, among white individuals ages 18 to 44 the incidence increased 67 percent. The increasing incidence was most dramatic for white females ages 18 to 44. They had a percentage change of 111 percent. Interestingly, the incidence decreased for African American and other racial groups.

Historically, oral tongue cancer has been strongly associated with heavy tobacco and alcohol use. Other epidemiological studies have related the decreasing incidence of oral tongue cancer in the United States to the decreased use of tobacco products. Though the UNC research team verified the known decreasing incidence of oral tongue cancer, they were surprised to observe an increasing incidence in young white individuals, specifically young white females.

"Lately we have been seeing more oral tongue cancer in young white women in our clinic. So we looked at the literature, which reported an increase in oral tongue squamous cell carcinoma in young white individuals but couldn't find any information about gender-specific incidence rates, so we decided we should take a look at the SEER data," said Bhisham Chera, MD, lead author on the study and assistant professor in the Department of Radiation Oncology.

Over the past decade an association between the human papilloma virus with squamous cell carcinoma of the tonsil and tongue has been observed. Patients with human papilloma virus associated oral squamous cell carcinoma are typically male, white, non-smokers, non-drinkers, younger in age and have higher socioeconomic status. The researchers at UNC have preliminarily tested the cancers of the oral tongue of their young white female patients and have not found them to be associated with the virus. Other institutions have also noted the absence of the virus in young females with oral tongue cancer. The UNC researchers have also anecdotally observed that these young white female patients are typically non-smokers and non-drinkers.

"Our findings suggest that the epidemiology of this cancer in young white females may be unique and that the causative factors may be things other than tobacco and alcohol abuse. Based on our observations and the published data, it appears that these cases may not be associated with the human papilloma virus. We are actively researching other causes of this cancer in this patient population." he added.

Though the increasing rate of oral tongue cancer in young white females is alarming oral tongue cancer is a rare cancer, relative to breast, lung, prostate, and colorectal cancer. "Primary care physicians and dentist should be aware of this increasing incidence and screen patients appropriately," states Dr. Chera. Oral tongue cancer is typically treated with surgery first followed by radiation and, in some cases, chemotherapy.


'/>"/>

Contact: Ellen de Graffenreid
edegraff@med.unc.edu
919-962-3405
University of North Carolina School of Medicine
Source:Eurekalert

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2017)... ... 2017 , ... "TransFreeze Volume 3 is a self animating masking transition which allows users to ... X," said Christina Austin - CEO of Pixel Film Studios. , TransFreeze Volume 3 ... one clip to the next. , To use “Cut-Out First” presets, choose a ...
(Date:1/13/2017)... (PRWEB) , ... January 13, 2017 , ... The 18th ... Avenida America hotel on March 3-4, 2017. This Congress is expertly designed to ... the management of patients with lung cancer. , Chaired by Dr. Giorgio V. Scagliotti, ...
(Date:1/13/2017)... ... 2017 , ... KOAMTAC ®, Inc., a leading manufacturer of Bluetooth barcode ... scanner and data collector at the National Retail Federation’s Big Show (NRF17) held January ... to the market’s need for more compact and rugged devices for collecting barcode data ...
(Date:1/13/2017)... PA (PRWEB) , ... January 13, 2017 , ... An inventor from Pahrump, Nev., used ... others. "My urologist had me wear a Foley catheter and urine bag for a half ... and uncomfortable, so I decided that there should be a better way to do this." ...
(Date:1/13/2017)... MN (PRWEB) , ... January 13, 2017 , ... People ... to endure jolts of pain whenever they brush their teeth. Sadly, most dental hygiene ... who have sensitive gums and teeth. For these people, continuing their daily oral care ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... LONDON , Jan. 16, 2017 ... delivering devices used for administering medications in a ... mainly used for therapeutic purposes in critical care, ... are required to make patient,s feel comfortable and ... medical errors which would lead to serious life ...
(Date:1/16/2017)...   The Harrington Discovery Institute at ... , has announced the 2017 recipients of Harrington ... physician-scientists whose research shows promise to advance the ... Institute – part of The Harrington Project for ... academic medicine: to advance early breakthroughs into the ...
(Date:1/16/2017)... According to the new market research report "Display Controller Market by ... LCD Controller), Application (Industrial Control, Medical Equipment, Automotive, Mobile Communication), and Geography ... to grow from USD 17.26 Billion in 2015 to reach USD 32.24 ... Continue Reading ... ...
Breaking Medicine Technology: