Navigation Links
UNC study: Common vaginal infection may increase risk of HIV infection
Date:7/31/2008

CHAPEL HILL A common vaginal infection may make women more susceptible to contracting HIV, the virus that causes AIDS, University of North Carolina at Chapel Hill School of Public Health researchers have found.

An analysis of 23 published studies, including data from more than 30,700 women from around the world, showed that women with bacterial vaginosis the most common type of vaginosis in women of reproductive age were more likely than others to be infected with HIV. The association between bacterial vaginosis (BV) and HIV was stronger for women without high-risk sexual behavior.

The results of this meta-analysis have been published in the peer-reviewed journal, AIDS.

"Given that bacterial vaginosis and HIV infection are both transmitted sexually, it is difficult to determine whether associations found are causal, or if there is some other reason why women with BV are more likely that others to become infected with HIV," said Jennifer S. Smith, epidemiology research assistant professor in the UNC School of Public Health. "If additional follow-up studies show that there was a relationship between BV and the risk of incident HIV infection, though, then increasing the treatment of BV could be considered for the future prevention of HIV infection."

Bacterial vaginosis is an imbalance in the type of bacteria normally found in the vagina. BV has been shown to cause gynecological and obstetrical problems including preterm delivery, pelvic inflammatory disease and upper genital tract infections.

Other research has shown that BV results in several changes in the vagina that could explain why it increases the risk of HIV, such as a depletion in a type of bacteria that are believed to play a role in defending the vagina against microorganisms including HIV, and higher pH levels that may increase the adherence and survival of the virus.

The studies analyzed by Smith and colleagues included women from the U.S., Malawi, Kenya, South Africa, Thailand, Uganda, Zimbabwe, Tanzania, South Africa, Nigeria, Burkina Faso and Gambia. Prevalence of BV in women in these countries ranged from about 11 percent to as high as 70 percent.

The analysis of data indicates that BV increases the risk of acquiring HIV by about 60 percent. The association between BV and HIV infection was weaker in high HIV-risk groups, Smith said. "That may be because women in high-risk groups have a greater risk of acquiring HIV from causes other than BV. This could be helpful information in identifying which populations would be helped most through targeted bacterial vaginosis control measures."


'/>"/>

Contact: Patric Lane
patric_lane@unc.edu
919-962-8596
University of North Carolina at Chapel Hill
Source:Eurekalert

Related medicine news :

1. U of M study: Early treatment can reverse heart damage
2. New study: Pine bark reduces perimenopausal symptoms
3. U of M study: Health food supplement may curb addiction of pathological gamblers
4. New study: Pine bark extract reduces ADHD symptoms in children
5. Kaiser Permanente study: Alcohol amount, not type -- wine, beer, liquor -- triggers breast cancer
6. UGA study: Youth exposed to smokeless tobacco ads despite settlement
7. New National Medicaid Study: Minnesota Under Funds Seniors Nursing Home Care $167 Million Annually
8. Study: Modafinil is effective in treating excessive sleepiness
9. Breaking Study: Masimo Pleth Variability Index (PVI) Shown Effective in Noninvasive Detection of Changes in Ventricular Preload and Fluid Volume
10. New study: pine bark extract boosts nitric oxide production
11. Study: HPV test beats Pap in detecting cervical cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... ... , ... The event is being held on April 7, 2016 from 5:30 ... Over Parkinson’s will fund nearly $100,000 for research for the care and cure of ... and is the architect of this informative event to raise awareness and funds for ...
(Date:2/5/2016)... ... February 05, 2016 , ... Freed-Hardeman University President Joe ... signed a joint enrollment and degree completion agreement. The agreement, which begins ... degrees at FHU|Dickson. , The agreement allows students to be jointly admitted ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... franchises from across the country gathered at the La Valencia Hotel in San ... PROSHRED Chicago was named the year’s most outstanding franchise, walking away with ...
(Date:2/5/2016)... ... February 05, 2016 , ... Boar’s Head Brand®, one ... time for this weekend’s Big Game. Take the stress out of your party preparation ... your guests happy at every stage of the game. , “The key to hosting ...
(Date:2/5/2016)... ... February 05, 2016 , ... Stuart Bentkover, MD, FACS is ... to provide the most effective tattoo removal today, Dr. Bentkover is the only doctor ... by Cynosure, the PicoSure has been approved by the Food and Drug Administration (FDA) ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... 4, 2016  Omnicell, Inc. (NASDAQ: OMCL ), a ... healthcare systems, today announced results for its fiscal year ... --> --> GAAP results: Revenue for ... $5.1 million or 4.1% from the third quarter of ... fourth quarter of 2014. Revenue for the year ended ...
(Date:2/4/2016)... Feb. 4, 2016 In response to the opioid ... Deputy Commissioner for Medical Products and Tobacco, along with other ... the agency,s approach to opioid medications. The plan will focus ... patients in pain access to effective relief. ... , Re-examine the risk-benefit paradigm for opioids and ensure ...
(Date:2/4/2016)... -- --> --> ... Automated External Defibrillator (AED) Market by Product (Semi-Automated External ... Hospitals, Homecare & Nursing Homes) - Forecast to 2019", ... and segments the concerned market with an analysis and ... grow to about $367.0 million by 2019, at a ...
Breaking Medicine Technology: