Navigation Links
UNC receives more than $40 for global clinical trials unit to treat and prevent HIV
Date:2/26/2014

The University of North Carolina at Chapel Hill has received a seven-year, more than $40 million award from the National Institutes of Health for a clinical trials unit that will implement the scientific agendas of five NIH networks devoted to HIV/AIDS treatment, prevention, and cure research.

UNC has had a continuously funded AIDS Clinical Trials Unit since 1987. The latest competitive funding renewal consolidates HIV clinical research operations in North Carolina, Malawi, and Zambia into a Global HIV Prevention and Treatment Clinical Trials Unit (UNC Global CTU). The UNC Global CTU will receive approximately $5.5 million in the first year to continue and develop studies addressing the prevention, treatment, and cure of HIV infection.

"Researchers at Carolina have been at the forefront of the AIDS epidemic from day one," said Marschall Runge, MD, PhD, executive dean of the UNC School of Medicine. "This award recognizes the scientific leadership and global reach of the UNC HIV/AIDS enterprise."

UNC is home to a top-10 ranked HIV/AIDS program, involving dozens of researchers from laboratory scientists and clinicians to epidemiologists and policy experts. Between 2008 and 2012, the university received approximately $430 million in external research funding for HIV. The landmark study HPTN 052named "Breakthrough of the Year" in 2011was spearheaded by UNC researchers. It showed that HIV treatment prevents transmission of the virus. UNC is also home to one of the largest HIV cure initiatives in the world.

The new grant provides funding through 2021 for five clinical research sites that make up the UNC Global CTU: Chapel Hill, Raleigh, and Greensboro, N.C.; Lilongwe, Malawi; and Lusaka, Zambia. The Southeastern United States and sub-Saharan Africa represent some of the most severely affected populations in the United States and worldwide.

The UNC Global CTU will lead clinical research that addresses treatment of HIV and associated illness in adults and children, including tuberculosis and viral hepatitis co-infections. Prevention research will include studies of behavior change, treatment as prevention, pre-exposure prophylaxis, HIV vaccines, and microbicides. Intensive clinical studies to advance a cure for HIV will be a critical focus of the unit.

The UNC Global CTU is led by three co-principal investigators from the UNC School of Medicine: Joseph Eron, MD, professor of medicine; Jeffrey Stringer, MD, professor of obstetrics and gynecology; and Mina Hosseinipour, MD, MPH, professor of medicine. The CTU is housed in the UNC Institute for Global Health & Infectious Diseases.

Although known for just 30 years, the human immunodeficiency virus has touched every corner of the globe, with 35 million people infected and 25 million lives lost. Not only is HIV a fierce biological opponent, but it is complicated by social factors related to stigma and the disproportionate burden on poor and marginalized populations.

"This disease will not be conquered with single-pronged solutions," said Eron, who also serves as CTU project director. "The complexity of HIV requires a multidisciplinary approach. Our CTU brings together a broad range of leading investigators whose expertise is focused on the greatest disease challenge of our time."

The CTU leadership team also includes site leaders Benjamin Chi, MD, associate professor of obstetrics and gynecology (Zambia); Francis Martinson, MD, PhD, research associate professor of medicine (Malawi); Cornelius van Dam, MD, clinical assistant professor of medicine (Greensboro); David Wohl, MD, MPH, associate professor of medicine (Chapel Hill); international operations director Irving Hoffman, PA, MPH, professor of medicine; and Cheryl Marcus, BSN, CTU coordinator and clinical research director.


'/>"/>

Contact: Lisa Chensvold
lisa_chensvold@med.unc.edu
919-843-5719
University of North Carolina Health Care
Source:Eurekalert  

Related medicine news :

1. Video by UC Riverside lab receives honorable mention in international competition
2. UCSF receives $50 million gift
3. JAX Genomic Medicines Jeffrey Chuang, Ph.D., receives $519,750 grant for RNA studies
4. Benaroya Research Institute receives 7-year award to lead Immune Tolerance Network
5. Louisiana Tech University professor, researcher receives prestigious Humboldt Prize
6. HMS receives RPB Medical Student Eye Research Fellowship
7. UT Southwesterns Dr. Beth Levine receives 2014 Stanley J. Korsmeyer Award
8. Sevocity EHR 11.4 Receives 2014 ONC HIT Certification
9. Grandmother Injured in San Antonio Dog Attack Receives $250K Settlement
10. Loyola receives Innovation Award for clinical research database
11. Olea Medical® Receives FDA 510(k) Clearance for Olea Sphere v2.3 Medical Imaging Software
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UNC receives more than $40 for global clinical trials unit to treat and prevent HIV
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Planet Fitness, ... the U.S., announced today its plans to open a flagship location in Covington, LA ... the former Rooms To Go store next to Office Depot in the Holiday Square ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) will ... during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual ... F. Collen, a pioneer in the field of medical informatics, this prestigious award is ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the Los ... article to the newly revamped Cosmetic Town journal section, featuring articles ... procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi says ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the ... – Miles by Moonlight to raise money for the American Heart Association Heart Walk. ... , Teams will work together to keep their treadmills moving for 5 hours. Treadmills ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United ... year. In some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and ... havens have extremely low property-tax rates, which contributes to the relatively lower cost ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... FRISCO, Texas , Oct. 11, 2017 /PRNewswire/ ... healthcare services, has amplified its effort during National ... patients about hereditary cancer risks. ... Journal of Clinical Oncology calculated that more than ... to have inherited mutations in BRCA1 or BRCA2 and ...
(Date:10/5/2017)...  In response to the nationwide opioid epidemic, ... (AAOMS) released prescribing recommendations that urge ibuprofen – ... a first-line therapy to manage a patient,s acute ... Recognizing the value and importance of the ... Acute and Postoperative Pain Management" stresses that practitioners ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: