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UNC-led study documents head and neck cancer molecular tumor subtypes
Date:2/22/2013

for recurrent patterns known as gene expression signatures, they were able to detect four gene expression subtypes. The subtypes are termed basal, mesenchymal, atypical, and classical based on similarities to established gene expression subtypes in other tumor types and expression patterns of specific genes.

In spite of being the seventh most common form of cancer in the United States, HNSCC is relatively under-studied in comparison to other tumor types, e.g. breast and lung. By leveraging the similarities found in the gene expression subtypes, the results of this study provide a connection to a range of well-established findings and additional insight into the disease.


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Contact: Dianne Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina Health Care
Source:Eurekalert  

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UNC-led study documents head and neck cancer molecular tumor subtypes
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