Navigation Links
UMMS and Lundbeck to explore potential targeted therapy for Huntington's disease
Date:1/28/2011

te at UCLA, an expert on HD animal models. The study is expected to be completed in 24 months.

"During my years helping patients who are living with HD, our understanding of the disease has increased dramatically and opened doors for new approaches to treating the condition," said Anne Young, MD, PhD, Chief of Neurology at

Massachusetts General Hospital. "In my opinion, this approach hits the disease right at its core. If this method can reduce the huntingtin protein throughout the brain, it carries the potential to change the course of the disease."

"The Hereditary Disease Foundation recognized the potential of RNA interference to cure Huntington's disease when it was just being discovered," says Nancy Wexler, Ph.D., President of the Hereditary Disease Foundation and Higgins Professor of Neuropsychology, Columbia University. "We organized the first Workshop in the world on this topic: 'RNA Modalities in Huntington's Disease Therapy,' in 2002. The Workshop was led by Phillip Sharp, who won the Nobel Prize in 1993. This was the same year that our research team discovered the HD gene, a breakthrough that made gene silencing possible. Neil Aronin was a critical Workshop participant. The Hereditary Disease Foundation funded the very first research projects proving that RNA inference cures HD in mice. Silencing the abnormal protein gets at the heart of the problem. It is a unique and revolutionary approach to finding treatments."

This collaboration is part of Lundbeck's Huntington's disease research initiative to identify and ultimately commercialize therapies that may slow or halt the progression of the disease. This research is driven by collaborations with academic institutions and companies with promising compounds in development.


'/>"/>

Contact: Alison Duffy
alison.duffy@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Gladstone and Lundbeck collaborate to study neurovascular disease
2. Explorers Bounty Puffed Fruit Snacks Helping Parents Battle Summer Obesity
3. Pittsburgh Neurosurgeons Explore Use of Drug that Illuminates Brain Tumor Cells To Guide Surgery
4. Unusual Place to Find Peace, Bliss and Explore Life's Mysteries
5. GE Healthcare, Intel and Mayo Clinic explore new models of health care delivery
6. DSM Personalized Nutrition Webinar Explores Benefits of Nutrition for Employee Health
7. Explore, Love, Happiness, Life Purpose, and Destiny with World Renowned Yogi and Mystic, Sadhguru
8. Lung cancer research explores the effects of patient attitudes on patient outcomes
9. Top Scientists Explore the Origin of Life in Annual Lasker Lecture at Scripps Research Institute Florida Campus
10. Study Explores Possibility of a Female Viagra
11. Health impacts of mobile phone use to be explored in huge new study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... Go Classy the Original Nudist Travel ... of their newest website http://www.Desire-Mexico.com . The seductively ... Desire Resorts have become the premier Nudist and Lifestyle ... total liberation while allowing you to enjoy a deluxe ... Classy Tours / Caribbean-Hideaways. He goes on to say ...
(Date:5/22/2013)... May 22 (HealthDay News) -- Fish oil supplements ... diabetes, new research suggests. The supplements, ... of a hormone called adiponectin that,s linked to ... this hormone in the bloodstream have also been ... "While prior animal studies found fish oil ...
(Date:5/22/2013)... 1,000 mg per day can help women live longer, ... Langsetmo, a Ph.D. Research Associate at McGill University, and ... Endocrinology and Metabolism in the Department of Medicine of ... Disorders axis at the Research Institute of the McGill ... Journal of Clinical Endocrinology & Metabolism (JCEM). ...
(Date:5/22/2013)... The newest member of TeethWhiteningforFree.com is Dr. ... Alabama graduate, Dr. Sanderson provides professional dental care to ... he extends complimentary teeth whitening to his patients who ... up. Only a dental professional can decide if the ... , Teeth whitening is an easy way ...
(Date:5/22/2013)... DiscountFurnaceFilter.com now offers a vast ... furnace filters, dehumidifiers, fans, aroma diffusers, dehumidifiers and ... Stadler Form's product line to their selection! Stadler ... aroma diffusers and dehumidifiers) to accentuate anyone’s home ... the perfect combination of design and functionality. Otto ...
Breaking Medicine News(10 mins):Health News:Go Classy Tours Announces the Launch of Their Newest Website for Desire Resorts Located in Mexico Clothing Optional/Aunaturel Resorts a Lovers Paradise 2Health News:Fish Oil Pills Might Cut Diabetes Risk, Researchers Say 2Health News:Calcium supplements linked to longer lifespans in women 2Health News:Dr. James Sanderson, Jr. Of SanDentistry in Hoover, Alabama Joins the TeethWhiteningforFree.com Family 2Health News:DiscountFurnaceFilter.com Now Offers Stadler Form Products - Providing Solutions to All Your Summer Needs 2
... 29 The National Patient,Safety Foundation,s theme this ... the importance of improving healthcare as a joint,effort ... Supporting National Patient Safety Awareness Week, March 2-8, ... ) urges communities to,actively partner with local hospitals ...
... Cardiogenesis,Corporation (Pink Sheets: CGCP), a leading developer ... today announced that,it will delay its earnings release ... full year ended December 31, 2007. The earnings ... Tuesday, March 4,2008., The Company noted that ...
... the Only Provider to Offer Practice Management and ... of Mental Health Care Providers, GREAT RIVER, ... provider of enterprise-wide software and services for health ... Therapist,Helper product suite and operations from Nightingale VantageMed,Corporation, ...
... PRINCETON, N.J., Feb. 29 Orchid Cellmark Inc.,(Nasdaq: ... testing,services, will release its fourth quarter and full year ... 7:00 am EST, and is,hosting a conference call and ... the same day. Management will discuss financial results for ...
... heart, liver and lung transplants at UCSF Medical ... according to new data compiled by the Scientific ... Released on January 11, the report measures performance ... facilities in the United States, including waiting list ...
... and benefits still outweigh risks, experts say , , FRIDAY, ... the risk for tendon problems, French researchers report. , ... rare, considering the huge number of statin prescriptions," wrote ... March issue of Arthritis Care and Research , ...
Cached Medicine News:Health News:Encision Supports National Patient Safety Awareness Week 2Health News:Cardiogenesis Corporation Reports Delay in Earnings Release and Conference Call 2Health News:Netsmart Technologies Acquires Largest Provider of Software for Private Practice Mental Health Providers and Therapists 2Health News:Netsmart Technologies Acquires Largest Provider of Software for Private Practice Mental Health Providers and Therapists 3Health News:Netsmart Technologies Acquires Largest Provider of Software for Private Practice Mental Health Providers and Therapists 4Health News:Orchid Cellmark to Announce Fourth Quarter and Full Year 2007 Financial Results on March 6, 2008 2Health News:Survival rates exceed national averages for UCSF heart, liver and lung transplant programs 2Health News:Cholesterol-Lowering Statins Tied to Tendon Woes 2Health News:Cholesterol-Lowering Statins Tied to Tendon Woes 3
(Date:5/22/2013)... STEPh, Inc., a full service medical communications ... web site ( http://www.stephreports.com ) dedicated to ... STEPh Reports STEPh Reports are comprehensive critical ... STEPh Report assesses the competitive landscape by individual drug ... and specific key issues.  STEPh Reports are written by ...
(Date:5/22/2013)... , May 22, 2013 MEDIFIRST SOLUTIONS, INC. ... update shareholders about some recent company developments. As Medifirst ... avenues of communication with shareholders. Integrating social media into ... Facebook page and will post updates on Twitter.  The ... is #medifirstusa. Says CEO ...
(Date:5/22/2013)... , May 22, 2013 Ranbaxy ... Sankyo Co., Ltd. (hereafter, Daiichi Sankyo), announced on ... in recent years to address past conduct under ... Daiichi Sankyo continues to support ... the conduct of the past which led to ...
Breaking Medicine Technology:Scientific and Technical Evaluation of Pharmaceuticals, Inc. [STEPh, Inc.], Launches New Competitive Intelligence Web Site 2Medifirst Solutions, Inc. Announces Update To Shareholders 2
... 9, 2011 ProTron Technologies announces a new approach ... the patented Stethotron® Cerebral Stethoscope. In the ... In 50% of ruptured aneurysms, patients in the age ... of the major factors leading to aneurysm is vascular ...
... Westside Medical Imaging of Beverly Hills announces the ... a 3 Tesla magnet to monitor the effects of cholesterol ... Hooman Madyoon and Michael Duffy of ... adopted 3 Tesla magnetic resonance imaging (MRI) using specialized vascular ...
Cached Medicine Technology:Westside Medical Imaging Uses High Resolution Magnetic Imaging to Monitor Effects of Cholesterol Drugs on Atherosclerosis 2
... the highest g-force ever. But optimal productivity ... Optima MAX combines maximum force, capacity, and ... that's worlds apart from any other system. ... enhanced efficiency, Optima takes productivity to the ...
... generating 694,000 x g at ... Beckman Coulter's Optima L-90K Ultracentrifuge ... separations in less time. This ... a broad range of superb ...
... With the ability to provide a simple, ... in lipemic samples), the Airfuge CLS delivers ... can be cleaned in 10 minutes, eliminating ... tabletop centrifuge: Reaches top speed in as ...
The Dimension RxL Max is an integrated chemistry system and is the most powerful and technologically advanced Dimension analyze with new standard for excellence in clinical diagnostics. Simply put, t...
Medicine Products: