Navigation Links
UIC in NIH-funded islet transplantation study for type 1 diabetes
Date:7/8/2008

The University of Illinois at Chicago is one of 11 centers in the United States, Canada, Sweden and Norway to participate in the Clinical Islet Transplant Consortium funded by the National Institutes of Health.

Consortium researchers have begun clinical studies to test new approaches to islet transplantation that may lead to improved outcomes and fewer side effects for adults with difficult-to-control type 1 diabetes.

Patients with type 1 diabetes depend on multiple daily insulin injections or an insulin pump because their own immune system destroys the insulin-producing cells of the pancreas. They often develop life-threatening complications, including damage to the heart and blood vessels, eyes, nerves and kidneys.

Islet transplantation offers the most promise for achieving insulin independence, glucose control and freedom from hypoglycemic attacks for type 1 diabetics, says Dr. Jos Oberholzer, principal investigator and director of cell and pancreas transplantation at UIC.

"This research will help us find the most effective combination of anti-rejection drugs to maximize islet engraftment while reducing toxic side effects," said Oberholzer.

"The ultimate goal is to refine islet transplantation and generate an unlimited supply of islets so that many more people would benefit from this treatment," he said.

Islet transplantation involves isolating islets from a donor pancreas and infusing the cells into the main blood vessel in the patient's liver. If the transplant is successful, the islets lodge in the small blood vessels of the liver and begin producing insulin. Patients must take drugs to suppress their immune system and prevent rejection of the islets. In some cases, patients require more than one infusion of donor islets to produce enough insulin.

At UIC, patients will be enrolled in three protocols to evaluate a combination of different medications to protect the newly transplanted islet cells.


'/>"/>

Contact: Sherri McGinnis Gonzalez
smcginn@uic.edu
312-996-8277
University of Illinois at Chicago
Source:Eurekalert

Related medicine news :

1. NIH-funded Vanderbilt Research Seeks Ways to Avoid Information Overload in Health Care Choices Among Seniors
2. The new source of islet cells
3. Living donors may be best source of insulin-producing islets for diabetes treatment
4. Studies test new approaches to islet transplantation
5. Islet Cell Transplants Aid Type 1 Diabetics
6. Promising advances in islet cell transplants for diabetes
7. A rare association: Non-islet cell tumor hypoglycemia
8. American Society of Transplantations Past President Testifies Before Congress at Forum on Organ Donation
9. Patients over age 60 do well after liver transplantation
10. No racial differences seen in outcomes after liver transplantation
11. Predicting survival after liver transplantation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... The ... in Dallas that it will receive two significant new grants to support its ... PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists for ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... ... is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is ...
(Date:6/24/2016)... ... 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ... raise to $12 an hour by 2020 and then adjusting it yearly to increase at ... the minimum wage, assure the wage floor does not erode again, and make future increases ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... today at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra ... authored journal articles published in Emergency Medicine Practice and Pediatric Emergency ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions today ... cultivation and processing operations at its production facility, and opened its first two ... the manufacturer of a complete system of proactive air and surface purification solutions ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Roche (SIX: RO, ROG; ... for its Elecsys BRAHMS PCT (procalcitonin) assay as a ... septic shock. With this clearance, Roche is the first ... integrated solution for sepsis risk assessment and management. ... infection and PCT levels in blood can aid clinicians ...
(Date:6/23/2016)... Bracket , a leading clinical trial technology ... outcomes platform, Bracket eCOA (SM) 6.0, at the 52 ... 30, 2016 in Philadelphia , Pennsylvania.  A ... product of its kind to fully integrate with RTSM, will ... 6.0 is a flexible platform for electronic clinical outcomes assessments ...
(Date:6/23/2016)... June 23, 2016 Revolutionary technology ... Oticon , industry leaders in advanced audiology and ... Oticon Opn ™, the world,s first internet connected ... for IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... a number of ,world firsts,: , TwinLink™ ...
Breaking Medicine Technology: