Navigation Links
UIC in NIH-funded islet transplantation study for type 1 diabetes
Date:7/8/2008

The University of Illinois at Chicago is one of 11 centers in the United States, Canada, Sweden and Norway to participate in the Clinical Islet Transplant Consortium funded by the National Institutes of Health.

Consortium researchers have begun clinical studies to test new approaches to islet transplantation that may lead to improved outcomes and fewer side effects for adults with difficult-to-control type 1 diabetes.

Patients with type 1 diabetes depend on multiple daily insulin injections or an insulin pump because their own immune system destroys the insulin-producing cells of the pancreas. They often develop life-threatening complications, including damage to the heart and blood vessels, eyes, nerves and kidneys.

Islet transplantation offers the most promise for achieving insulin independence, glucose control and freedom from hypoglycemic attacks for type 1 diabetics, says Dr. Jos Oberholzer, principal investigator and director of cell and pancreas transplantation at UIC.

"This research will help us find the most effective combination of anti-rejection drugs to maximize islet engraftment while reducing toxic side effects," said Oberholzer.

"The ultimate goal is to refine islet transplantation and generate an unlimited supply of islets so that many more people would benefit from this treatment," he said.

Islet transplantation involves isolating islets from a donor pancreas and infusing the cells into the main blood vessel in the patient's liver. If the transplant is successful, the islets lodge in the small blood vessels of the liver and begin producing insulin. Patients must take drugs to suppress their immune system and prevent rejection of the islets. In some cases, patients require more than one infusion of donor islets to produce enough insulin.

At UIC, patients will be enrolled in three protocols to evaluate a combination of different medications to protect the newly transplanted islet cells.


'/>"/>

Contact: Sherri McGinnis Gonzalez
smcginn@uic.edu
312-996-8277
University of Illinois at Chicago
Source:Eurekalert

Related medicine news :

1. NIH-funded Vanderbilt Research Seeks Ways to Avoid Information Overload in Health Care Choices Among Seniors
2. The new source of islet cells
3. Living donors may be best source of insulin-producing islets for diabetes treatment
4. Studies test new approaches to islet transplantation
5. Islet Cell Transplants Aid Type 1 Diabetics
6. Promising advances in islet cell transplants for diabetes
7. A rare association: Non-islet cell tumor hypoglycemia
8. American Society of Transplantations Past President Testifies Before Congress at Forum on Organ Donation
9. Patients over age 60 do well after liver transplantation
10. No racial differences seen in outcomes after liver transplantation
11. Predicting survival after liver transplantation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... Mateo, CA (PRWEB) , ... May 24, 2016 ... ... dedicated to advancing the science and clinical practice of radiosurgery, is recognizing five ... of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). The awards will be ...
(Date:5/24/2016)... (PRWEB) , ... May 24, 2016 , ... ... for 2016 increased by 9.3 million people, or 10% over last year, according ... of people covered under group policies was comparatively stable, with a slight decrease ...
(Date:5/24/2016)... OR (PRWEB) , ... May 24, 2016 , ... ... welcomed Peggy Kinst, a wellness specialist for forty years and a trainer for ... the Sharon Kleyne Hour Radio Talk Show on May 16, 2016. , Formerly ...
(Date:5/24/2016)... ... ... WaterAid launched the #perioddrama campaign to mark Menstrual Hygiene Day on May 28 ... world who do not have access to a toilet, even when they’re on their periods. ... #perioddrama. The (sometimes hilarious) results help shine a light on the awkwardness that women face ...
(Date:5/24/2016)... (PRWEB) , ... May 24, 2016 , ... In light ... residents aware of the potential of contaminated well water throughout the Houston area. , ... supplied with well water that’s exposed to contaminants. Residents may not even be aware ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 24, 2016 ARANZ Medical  Ltd ... healthcare sector, has been named the Coretex Hi-Tech Emerging Company ... Dr Bruce Davey , CEO of ARANZ ...  It,s really good to be recognised for the work we ... are used in 35 countries around the world from Sub-Saharan ...
(Date:5/24/2016)... , May 24, 2016 ... doble terapia del mundo, introduce catéteres para la ... OrbusNeich, una compañía global especializada en el ... ha expandido su cartera incluyendo productos para tratar ... y Scoreflex™ PTA son los dispositivos de primera ...
(Date:5/23/2016)... According to a new ... Product (Wheelchair, Scooters, Medical Beds, Bathroom Safety, Mechanical, ... Wound), Accessories (Lifting, Transfer) & by End User ... MarketsandMarkets, the patient handling equipment market is expected ... a CAGR of 10.5% during the forecast period ...
Breaking Medicine Technology: