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UI researchers find early predictor for preeclampsia
Date:7/8/2014

tin biomarker is also elevated in urine, and could therefore be used in a simple home test kit.

While there are currently no treatments for preeclampsia other than premature delivery of the baby, the researchers are also investigating new drug targets. The group has demonstrated that infusion of vasopressin into pregnant mice causes all of the major symptoms of preeclampsia. Until this discovery, there was no effective animal model of the early-pregnancy events that precipitate preeclampsia.

"We've broken the circle of 'no test, no model, no cure' which has plagued the preeclampsia field for centuries," notes Grobe. "Suddenly we have identified a hormone that is elevated well ahead of the disorder, and have demonstrated that this hormone can cause the symptoms. It is only a matter of time before we can therapeutically target this system as a preventative or curative intervention."


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Contact: Molly Rossiter
molly-rossiter@uiowa.edu
319-356-7127
University of Iowa Health Care
Source:Eurekalert

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