Navigation Links
UH Rainbow to study African-Americans' response to asthma medications
Date:5/2/2014

In a first-of-its-kind clinical trial, asthma researchers at University Hospitals Rainbow Babies & Children's Hospital (UH Rainbow) will evaluate treatment guidelines for African American children and young adults with asthma.

"Each year African Americans experience more asthma-related urgent care visits, hospitalizations and death rates compared to Caucasians," says James Chmiel, MD, Clinical Director of Pediatric Pulmonology at UH Rainbow and principal investigator of the UH Rainbow study site. Dr. Chmiel, who is also Associate Professor of Pediatrics at Case Western Reserve University School of Medicine, says one possible explanation is that African Americans respond differently to asthma therapies.

The study of Best African American Response to Asthma Drugs (BARD) will examine whether African Americans respond differently to asthma therapies compared to Caucasians and will help to identify the best add-on therapy based on the patients' age. Researchers are recruiting African American patients five years of age and older who have asthma. UH Rainbow is conducting this study as a member of nine partnerships known as AsthmaNet. AsthmaNet is a network of asthma researchers across the country conducting this and other asthma research studies, and is funded by the National Institutes of Health.

National asthma guidelines recommend increasing inhaled corticosteroids (ICS) or adding a long-acting beta agonist (LABA) to treat patients who have difficulty controlling symptoms on low doses of ICS. However, these guidelines are based on studies conducted in populations that were predominantly non-black. Evidence suggests African Americans may not respond to changes in asthma medications the same way other races do.

BARD will enroll several hundred patients nationally for 18 months. Study participants will receive low dose ICS, and if their asthma is inadequately controlled, they will receive four different treatments (low dose ICS plus LABA, medium dose ICS, medium dose ICS plus LABA, and high dose ICS) over four separate 14-week treatment periods.

"Results of the BARD study will allow for evidence-based recommendations for the use of asthma medications in African Americans, significantly impacting national asthma guidelines," says Dr. Chmiel.


'/>"/>

Contact: Katelyn McCarthy
katelyn.mccarthy@uhhospitals.org
216-767-8582
University Hospitals Case Medical Center
Source:Eurekalert

Related medicine news :

1. Rainbow research reveals young children with asthma visit emergency department most often
2. Voices Against Brain Cancer Applauds Mother For Starting Riah’s Rainbow Organization
3. Historic Lodge at Rainbow Trout Ranch Celebrates Eighty Five Years in Southern Colorado
4. Study shows link between sleep apnea and hospital maternal deaths
5. Vanderbilt study explores genetics behind Alzheimers resiliency
6. Study: Custom-made mouthguards reduce athletes risk of concussion
7. Study: Low-fat diet helps fatigue in people with MS
8. Space Station study seeks how plants sense up and down
9. Study confirms increased prevalence of GI symptoms among children with autism
10. Anti-smoking TV ads should use anger, Dartmouth-Cornell study suggests
11. $2.3M study to examine how neighborhoods influence child maltreatment rates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/21/2017)... ... February 21, 2017 , ... Individuals who have been diagnosed ... surgery, treatment, therapy and management. Regular exercise in proper environments has been shown ... their diseases. On February 23, 2017, 1:00-2:00 p.m. E.S.T., a dynamic HydroWorx ...
(Date:2/21/2017)... NJ (PRWEB) , ... February 21, 2017 , ... ... research and conference coverage in veterinary medicine, will be launching its first bi-monthly ... animal health and medicine, business and practice management, and One Health. , ...
(Date:2/21/2017)... ... 2017 , ... Atlanta-based Jvion, the leading cognitive clinical science ... practice. Predixion, which raised $42M+ to date, received $20M in its third ... Ventures, and Software AG , will bring top industry talent and an impressive ...
(Date:2/21/2017)... ... February 21, 2017 , ... A February 6 article on Healio ... It found that the treatments have led to significant improvements in weight loss and ... efforts. It also noted very few problematic results relating to the treatment. Beverly Hills ...
(Date:2/20/2017)... Ill. (PRWEB) , ... February 20, 2017 , ... ... to reduce the rate at which women are called back for additional examinations ... journal Radiology . , In 2011, the U.S. Food and Drug Administration ...
Breaking Medicine News(10 mins):
(Date:2/21/2017)... MELBOURNE, Australia , Feb. 21, 2017  IBM (NYSE: ... IBM Watson,s ability to detect abnormalities of the eye,s retina. ... trained a research version of Watson to recognize abnormalities in ... insights and speed in their early identification of patients who ... glaucoma, a leading cause of blindness in the developed world. ...
(Date:2/21/2017)... Medical Oxygen Concentrators Market: Overview ... Medical oxygen concentrators are used by patients ... having low level of oxygen in their blood ... are to be used only with prescription and ... concentrators work either on rechargeable lithium batteries or ...
(Date:2/21/2017)...   BeyondSpring Pharmaceuticals , a clinical stage ... immuno-oncology cancer therapies, today announced that the Company,s ... 2 trial of BeyondSpring,s innovative lead asset, ... lung cancer (NSCLC) with Docetaxel has been selected ... Immuno-Oncology Symposium in Orlando, Fla. ...
Breaking Medicine Technology: