Navigation Links
UH Rainbow to study African-Americans' response to asthma medications
Date:5/2/2014

In a first-of-its-kind clinical trial, asthma researchers at University Hospitals Rainbow Babies & Children's Hospital (UH Rainbow) will evaluate treatment guidelines for African American children and young adults with asthma.

"Each year African Americans experience more asthma-related urgent care visits, hospitalizations and death rates compared to Caucasians," says James Chmiel, MD, Clinical Director of Pediatric Pulmonology at UH Rainbow and principal investigator of the UH Rainbow study site. Dr. Chmiel, who is also Associate Professor of Pediatrics at Case Western Reserve University School of Medicine, says one possible explanation is that African Americans respond differently to asthma therapies.

The study of Best African American Response to Asthma Drugs (BARD) will examine whether African Americans respond differently to asthma therapies compared to Caucasians and will help to identify the best add-on therapy based on the patients' age. Researchers are recruiting African American patients five years of age and older who have asthma. UH Rainbow is conducting this study as a member of nine partnerships known as AsthmaNet. AsthmaNet is a network of asthma researchers across the country conducting this and other asthma research studies, and is funded by the National Institutes of Health.

National asthma guidelines recommend increasing inhaled corticosteroids (ICS) or adding a long-acting beta agonist (LABA) to treat patients who have difficulty controlling symptoms on low doses of ICS. However, these guidelines are based on studies conducted in populations that were predominantly non-black. Evidence suggests African Americans may not respond to changes in asthma medications the same way other races do.

BARD will enroll several hundred patients nationally for 18 months. Study participants will receive low dose ICS, and if their asthma is inadequately controlled, they will receive four different treatments (low dose ICS plus LABA, medium dose ICS, medium dose ICS plus LABA, and high dose ICS) over four separate 14-week treatment periods.

"Results of the BARD study will allow for evidence-based recommendations for the use of asthma medications in African Americans, significantly impacting national asthma guidelines," says Dr. Chmiel.


'/>"/>

Contact: Katelyn McCarthy
katelyn.mccarthy@uhhospitals.org
216-767-8582
University Hospitals Case Medical Center
Source:Eurekalert

Related medicine news :

1. Rainbow research reveals young children with asthma visit emergency department most often
2. Voices Against Brain Cancer Applauds Mother For Starting Riah’s Rainbow Organization
3. Historic Lodge at Rainbow Trout Ranch Celebrates Eighty Five Years in Southern Colorado
4. Study shows link between sleep apnea and hospital maternal deaths
5. Vanderbilt study explores genetics behind Alzheimers resiliency
6. Study: Custom-made mouthguards reduce athletes risk of concussion
7. Study: Low-fat diet helps fatigue in people with MS
8. Space Station study seeks how plants sense up and down
9. Study confirms increased prevalence of GI symptoms among children with autism
10. Anti-smoking TV ads should use anger, Dartmouth-Cornell study suggests
11. $2.3M study to examine how neighborhoods influence child maltreatment rates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions ... initiated cultivation and processing operations at its production facility, and opened its first ... is the manufacturer of a complete system of proactive air and surface purification ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that ... PCT (procalcitonin) assay as a dedicated testing solution for ... clearance, Roche is the first IVD company in the ... risk assessment and management. PCT is a ... in blood can aid clinicians in assessing the risk ...
(Date:6/23/2016)... 23, 2016 Capricor Therapeutics, ... a biotechnology company focused on the discovery, development ... patient enrollment in its ongoing randomized HOPE-Duchenne clinical ... 50% of its 24-patient target. Capricor expects the ... quarter of 2016, and to report top line ...
(Date:6/23/2016)... Pa. , June 23, 2016 Bracket ... will launch its next generation clinical outcomes platform, Bracket eCOA ... Meeting held on June 26 – 30, 2016 in ... the first electronic Clinical Outcome Assessment product of its kind ... Booth #715. Bracket eCOA 6.0 is a flexible ...
Breaking Medicine Technology: