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UGR and Michael J. Fox Foundation take a step forward in the study of Parkinson's disease
Date:11/9/2012

ur parameters through asymmetric Levy-stable distributions.

In this study, stable-distribution parameters, concretely those of scale and position, are used to linearly convert the intensity values for each voxel. This conversion is performed in such a way that the new intensitivy histograms for each brain image have the same values for the parameters position and dispersion. The proposed method has a better performance that the traditional intensity normalization method, which is based on the ration between the intensity values of specific and non-specific brain regions.

This paper, titled Linear intensity normalization of FP-CIT SPECT brain images using the alpha-stable distribution, D. Salas-Gonzalez, J. M. Grriz, J. Ramrez, I. A. Illn, E.W. Lang, and the Parkinson's Progression Markers Initiative (PPMI), has been recently accepted for publication in the journal Neuroscience, which is the top journal in the Thomson/ISI ranking, with 5,898 impact points.


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Contact: Juan Manuel Grriz Sez
gorriz@ugr.es
34-958-243-271
University of Granada
Source:Eurekalert

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