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UGR and Michael J. Fox Foundation take a step forward in the study of Parkinson's disease
Date:11/9/2012

be processed by pattern-recognition machine, which allow an objective analysis of data.

A collaborative work with Virgen de la Victoria Hospital

The latest study conducted by this research group (Automatic assistance to Parkinson's disease diagnosis in DaTSCAN SPECT imaging. I. A. Illn, J. M. Grriz, J. Ramrez, F. Segovia, J. M. Jimnez-Hoyuela, and S. J. Ortega Lozano Med. Phys. 39, 5971 (2012)) presents a computer procedure that does not need the intervention of an expert (normalization, location of relevant regions, "clinical eye"...). In addition, this new technique systematically analyzes the effect of the different elements involved in the building process of the computer-assisted diagnosis technique on the accuracy of the final diagnosis. As a result, the technique proposed may exceed 90% of accuracy in the diagnosis of PD with the right selection of elements, and with the additional advantage of being a robust and simple computer software.

Similarly, the researchers at the research group SiPBA TIC 218 recently published the paper Improved Parkinsonism diagnosis using a partial least squares based approach. (F. Segovia, J. M. Grriz, J. Ramrez, I. lvarez, J. M. Jimnez-Hoyuela, and S. J. Ortega, Med. Phys. 39, 4395. 2012), an enhanced versin of the former paper with the same title. In this paper, researchers propose a method consisting on separating brain hemispheres to fulfill two goals: firstly to correctly diagnose AD when it only affects one hemisphere (in many patients, PD evolves asymmetrically during the first stages)

A Paper Accepted for the Prestigious Journal Neuroimage

The group SiPBA has also developed a method for the linear normalization of intensity of FP-CIT SPECT-type brain images, which are generally used in the diagnosis of PD. The method proposed is based on experimental evidence that the histogram of image intensity values can be accurately adjusted using only fo
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Contact: Juan Manuel Grriz Sez
gorriz@ugr.es
34-958-243-271
University of Granada
Source:Eurekalert

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