Navigation Links
UGA vet school receives $1.18 million NIH grant for rabies vaccine investigations
Date:10/4/2007

The National Institute of Allergy and Infectious Diseases at the National Institutes of Health has awarded the University of Georgia College of Veterinary Medicine a $1.18 million grant to develop rabies virus vaccines. This award is the continuation of a previous four-year $837,000 grant issued by NIAID in 2002 to initiate the study.

Zhen Fu, professor of veterinary pathology at UGA, is the principal investigator of the study, along with Ralph Tripp, GRA Eminent Scholar and professor of infectious diseases at the College of Veterinary Medicine, who will investigate the immunological aspects. Fus study is seeking a less expensive and less invasive means of vaccinating humans and animals. The proposed vaccine will use a genetically modified form of the live virus; one that will be potent enough to establish immunity with fewer doses, yet is very safe because the genetic modification makes the virus unable to cause the disease.

Current rabies vaccines are made from an inactivated (killed) virus, explained Fu. Although they are effective, multiple vaccines are needed to induce protective immunity. Todays vaccines also are very expensive and require five doses for people bitten by rabid animals or animals suspected of being rabid, making it cost prohibitive for people in developing countries where rabies vaccines are needed the most.

According to the World Health Organization, approximately 55,000 human deaths, primarily in Asia and Africa, are attributed annually to rabies. As a zoonotic viral disease that attacks the central nervous system, rabies infects both domestic and wild animals. It may be transmitted through bites or, less commonly, through close contact with saliva of infected animals on open areas such as skin scratches.

We propose to develop a live form of the vaccine by incorporation of immune stimulatory molecules into the virus genome, said Fu. By doing so, we expect to develop a vaccine with greater potency yet reduced cost, because fewer doses will be required to establish immunity. These vaccines can also be used in domestic as well as wild animals to protect them from rabies infection.

This could potentially save millions of dollars worldwide. According to the Centers for Disease Control, the estimated public health costs associated with disease detection, prevention, and control have risen to more than $300 million annually. These costs include the vaccination of companion animals, animal control programs, maintenance of rabies laboratories, and medical costs, such as those incurred for rabies post-exposure prophylaxis. Although the cost varies, a course of rabies immune globulin and five doses of vaccine given over a four-week period typically exceeds $1,000.

The College of Veterinary Medicine is dedicated to improving the health of animals and humans, said Dean Sheila W. Allen. That the National Institutes of Health has awarded another substantial grant for the study of rabies demonstrates their continued confidence in our researchers to find treatments and cures for diseases that affect both animals and people.


'/>"/>

Contact: Tracy Giese
tgiese@uga.edu
706-583-5485
University of Georgia
Source:Eurekalert

Related medicine news :

1. School Children Put To Risk Due To Shortage Of Nurses
2. Schools and Bars closed in Rwanda due to Cholera outbreak
3. Does Success in School Differ From the Real World Success ?
4. Preschoolers eat more when served in bigger helpings
5. Watching TV in the bedroom can lower children’s school performanc
6. Exposure to Pesticides in Schools Produces Illnesses Among Employees, Students
7. Adolescents Who Walk To School Are Fitter, More Active
8. Safe Neighborhood Means Less TV For Preschool Children
9. Popularity Among Peers Increases Susceptibility To Smoking Habit Among School Children
10. Vitamin filled nutrition candy for School children
11. Fish Oil supplementation reduces physical aggression in school children’
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... TORONTO, ONTARIO, CANADA (PRWEB) , ... July 21, ... ... repair a torn anterior cruciate ligament (ACL) offer patients improved quality of life ... Orthopaedic Society for Sports Medicine’s Annual Meeting in Toronto, Ontario, Canada. The ...
(Date:7/20/2017)... ... ... ChenMed , a leading provider of value-based care for seniors, today announced ... Chief Medical Officer. Dr. McCarter, formerly Associate Professor of Family Medicine at the ... for the UVA Health System, brings 30 years of highly relevant experience to his ...
(Date:7/20/2017)... ... July 20, 2017 , ... Coats ... is pleased to announce their expansion to the Midwest with the establishment of ... Hollis and Ronald Bell, and of counsels, John Peck and Robert Bruns, will ...
(Date:7/20/2017)... ... July 20, 2017 , ... Team Type 1 Foundation, a nonprofit organization pursuing ... by diabetes, is teaming up with a Microsoft Corp. employee-led hackathon team for the ... 24th. , “Team Type 1’s mission overlaps seamlessly with Microsoft’s mission to empower ...
(Date:7/20/2017)... (PRWEB) , ... July 20, 2017 , ... ... about the introduction of bipartisan House and Senate legislation in support of providing ... Congresswoman Robin Kelly (D-IL) introduced H.R. 2408, the “Protecting Girls’ Access to Education ...
Breaking Medicine News(10 mins):
(Date:7/6/2017)... ThriveRx, the nutrition division of Diplomat Specialty Infusion Group, is ... nutrition support. To celebrate its anniversary, ThriveRx recently launched a ... new look with improved organization to create the best user experience for ... ... "We,ve made several great strides ...
(Date:7/5/2017)... Wash. , July 5, 2017   BioLife ... leading developer, manufacturer and marketer of proprietary clinical grade ... cryopreservation freeze media ("BioLife"), today announced that it ... its debt holder and largest shareholder, to modify its ... Pursuant to the modification, WAVI agreed to exchange ...
(Date:6/30/2017)... N.C. , June 29, 2017  Axium Pharmaceuticals Inc. is ... developing improved novel formulations and alternative dosage forms of existing ... ... is based on our waterless self-nano emulsifying formula, which is ... with saliva. We believe the spray will provide fast onset ...
Breaking Medicine Technology: