Athens, Ga. New research from the University of Georgia has identified the neural pathways in an insect brain tied to eating for pleasure, a discovery that sheds light on mirror impulsive eating pathways in the human brain.
"We know when insects are hungry, they eat more, become aggressive and are willing to do more work to get the food," said Ping Shen, a UGA associate professor of cellular biology in the Franklin College of Arts and Sciences. "Little is known about the other halfthe reward-driven feeding behaviorwhen the animal is not so hungry but they still get excited about food when they smell something great.
The fact that a relatively lower animal, a fly larva, actually does this impulsive feeding based on a rewarding cue was a surprise."
The research team led by Shen, who also is a member of the Biomedical and Health Sciences Institute, found that presenting fed fruit fly larvae with appetizing odors caused impulsive feeding of sugar-rich foods. The findings, published Feb. 28 in Cell Press, suggest eating for pleasure is an ancient behavior and that fly larvae can be used in studying neurobiology and the evolution of olfactory reward-driven impulses.
To test reward-driven behaviors in flies, Shen introduced appetizing odors to groups of well-fed larvae. In every case, the fed larvae consumed about 30 percent more food when surrounded by the attractive odors.
But when the insects were offered a substandard meal, they refused to eat it.
"They have expectations," he said. "If we reduce the concentration of sugar below a threshold, they do not respond anymore. Similar to what you see in humans, if you approach a beautiful piece of cake and you taste it and determine it is old and horrible, you are no longer interested."
Shen's team also tried to further define this phenomenonthe connection between excitement and expectation. He found when the larvae were presented with a brief odor, t
|Contact: Ping Shen|
University of Georgia