Navigation Links
UGA researchers 1 step closer to elusive cancer vaccine
Date:10/29/2007

Athens, Ga. When cells become cancerous, the sugars on their surfaces undergo distinct changes that set them apart from healthy cells. For decades, scientists have tried to exploit these differences by training the immune system to attack cancerous cells before they can spread and ravage the body.

Now, researchers at the University of Georgia Cancer Center have synthesized a carbohydrate-based vaccine that in mice has successfully triggered a strong immune response to cancer cells. The finding, published in the October issue of the journal Nature Chemical Biology, brings the scientists one step closer to a much-sought-after cancer vaccine.

In mice we can illicit very strong antibody responses and we have shown that the antibody responses are functional that they can kill cancer cells, said lead author Geert-Jan Boons, Franklin professor of chemistry.

Vaccines are currently use to prevent diseases by priming the immune system to recognize and attack a virus or bacteria. The vaccine that Boons and his team have developed, on the other hand, is a therapeutic vaccine that trains the bodys immune system to fight an existing disease.

The discovery in the 1970s of unique sugars on cancer cells set scientists in search of a way to get the immune system to recognize and attack cells that express these cancer-associated sugars. Until now, however, the results have been less than spectacular.

Cancer cells originate in the body, and the immune system leaves them alone because it distinguishes between the bodys own cells and foreign invaders such as viruses and bacteria.

Boons explained that early cancer vaccines were created by linking the tumor-associated carbohydrate with a foreign protein. The immune system, perhaps not surprisingly, attacked the protein and the linker molecules, but generally left the carbohydrate alone.

We needed to come up with a vaccine that does not give our immune system a chance t
'/>"/>

Contact: Sam Fahmy
sfahmy@uga.edu
706-542-5361
University of Georgia
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Researchers urge caution in using ear tube surgery
2. Researchers Scale to assess the Severity of Epilepsy in Kids
3. Researchers identify the early makers of Neonatal Sepsis
4. OHSU Researchers Announce New Discovery
5. Researchers Identify Gene Connected To Bipolar Disorder
6. Ecstasy shrinks brain!!-researchers unveil the secrets of MDMA.
7. Researchers trick Alzheimers Enzyme
8. Researchers find new HIV hiding place
9. Gene researchers make Malaria-resistant mosquito
10. New Hair in 15 Days Could Now Be A Possibility Say Researchers
11. Researchers developed world’s smallest toothbrus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/4/2015)... March 05, 2015 The emergence ... landscape over the past decade. The pharmaceutical world ... drug delivery in the form of liposomes and ... drugs with more safety and efficiency. In ... perhaps rely greatly upon the enhanced permeability and ...
(Date:3/4/2015)... Las Vegas, NV (PRWEB) March 04, 2015 ... good as the fight that is the main event. For ... announced and that fight will be for the UFC Featherweight ... against the brash, often out-spoken native of Ireland, Conor “Notorious” ... the MGM Grand Garden Arena in Las Vegas, NV. , ...
(Date:3/4/2015)... Florida (PRWEB) March 04, 2015 Ultraman ... a 6.2 mile swim, 261.4 mile bike, and 52.4 ... a total time of 24:45:45. , "This race was ... to my wonderful team and sponsors for supporting me ... Ultraman Florida 2015 had a total of 40 select ...
(Date:3/4/2015)... Dr. Christopher Asandra, M.D., Founder and Chief Medical ... the FDA’s recent decision to issue a warning ... FDA’s conclusions are not supported by science, and that ... deficiency. , “The FDA appears to have developed a ... Dr. Asandra. “There is not nearly enough evidence to ...
(Date:3/4/2015)... TROY Healthcare Solutions will be introducing TROY Secure ... of security for prescriptions, in Houston, Texas on Wednesday, ... located at 6633 Travis Street from 7 AM to ... Healthcare Solutions will host a continental breakfast. Starting at ... each hour to introduce attendees to TROY Secure Print ...
Breaking Medicine News(10 mins):Health News:Cancer Nanomedicine Marketplace Discussed by Kuick Research in Topical Study Recently Published at MarketPublishers.com 2Health News:Cancer Nanomedicine Marketplace Discussed by Kuick Research in Topical Study Recently Published at MarketPublishers.com 3Health News:Cheap UFC 189 Tickets: Jose Aldo vs. Conor McGregor UFC 189 Ticket Prices Slashed by Ticket Down for Featherweight Title 2Health News:Cheap UFC 189 Tickets: Jose Aldo vs. Conor McGregor UFC 189 Ticket Prices Slashed by Ticket Down for Featherweight Title 3Health News:Living Fuel Champion Christian Isakson Finishes Second In UltraMan Florida Test of Endurance 2Health News:NuMale’s Dr. Christopher Asandra: FDA Suffering from “Premature Equivocation” on Issue of Testosterone and Risks 2Health News:TROY Healthcare to Offer Prescription Solutions that can save a Hospital $100,000 2Health News:TROY Healthcare to Offer Prescription Solutions that can save a Hospital $100,000 3
... National Football League (NFL) will give a $1 million ... Traumatic Encephalopathy (CSTE) at Boston University School of Medicine ... funds will be used to continue the Center,s ground-breaking ... in athletes, in particular football players. CSTE researchers have ...
... Minn. -- The growing number of Americans with cardiovascular ... of chest pain. In a study published in the ... reported that patients dismissed from the hospital with noncardiac ... highlight a need for more aggressive cardiovascular risk factor ...
... for inflammation , TUESDAY, April 20 (HealthDay News) -- ... have something to do with components of virgin olive ... study reports. , "These findings strengthen the relationship between ... most basic level of healthy effects derived from virgin ...
... ... , ... 20, 2010 -- As the debate around legalization intensifies from coast to coast, CNBC.com ... of business. "Marijuana & Money" thoroughly examines the current marketplace as well as ...
... ... $2500 so far in a weight loss challenge, benefiting City CURE’s Whiz Kids program. Dr. ... is to raise $3000. City CURE is a non-profit organization in Cincinnati whose goal is ... ...
... "I was ... her pancreatic cancer. But the Chicago woman refused to give up in her fight ... Hepatobiliary Diseases at Northwest Community Hospital in Arlington Heights, where the expertise of Dr. Malcolm ... ...
Cached Medicine News:Health News:NFL gives $1 million unrestricted gift to Boston University to study impact of brain injuries 2Health News:NFL gives $1 million unrestricted gift to Boston University to study impact of brain injuries 3Health News:Outcomes of patients dismissed from the hospital with non-cardiac chest pain 2Health News:CNBC.com Presents "Marijuana & Money" 2Health News:CNBC.com Presents "Marijuana & Money" 3Health News:CNBC.com Presents "Marijuana & Money" 4Health News:Dr. Sachin Patel Partners with City CURE to Raise $3000 in a Pound-4-Pound Challenge Benefiting Whiz Kids 2Health News:Given No Chance to Survive with Pancreatic Cancer, Chicago Woman Finds New Life at Northwest Community Hospital 2Health News:Given No Chance to Survive with Pancreatic Cancer, Chicago Woman Finds New Life at Northwest Community Hospital 3
(Date:3/4/2015)...   Aratana Therapeutics, Inc . (NASDAQ: ... licensing, development and commercialization of innovative biopharmaceutical products for ... the Barclays Global Healthcare Conference to be ... Hotel in Miami , FL.  ... and Chief Executive Officer of Aratana Therapeutics, will provide ...
(Date:3/4/2015)... 2015  Results of the recent study, Results ... for Intra-Operative Positive Margin Detection , were presented as ... nd Annual Miami Breast Cancer Conference last week. ... Papa , MD, FACS, Professor of Surgery at the ... an analysis of MarginProbe,s efficiency and accuracy when used ...
(Date:3/4/2015)... 2015 Aethlon Medical, Inc. (OTCQB:AEMD), the pioneer in ... cancer, today announced that James A. Joyce , ... overview at the 27th Annual ROTH Conference on March ... Laguna Niguel, California . To learn more about ... A live webcast of the presentation will be ...
Breaking Medicine Technology:Aratana Therapeutics to Present at the Barclays Global Healthcare Conference 2New Study Shows Breast Re-excision Rates Significantly Reduced in 100 Consecutive Cases 2Aethlon Medical to Present at the 27th Annual ROTH Conference 2
... Plan for Biomarker Study -, MONTVALE, N.J., ... ) today announced that it plans to,conduct a ... nicotinic alpha-7,partial agonist, on two biomarkers of schizophrenia, ... schizophrenia. The biomarker study,and additional formulation and manufacturing ...
... Developed Test in the U.S. for Detecting the ... Mosquito-Borne Infectious Disease, ... diagnostics company of Quest Diagnostics (NYSE: DGX ),today announced ... mosquito-borne chikungunya virus. Commercial availability of,the molecular polymerase chain reaction ...
Cached Medicine Technology:Memory Pharmaceuticals & Roche Expand Development Program for MEM 3454 in Schizophrenia 2Memory Pharmaceuticals & Roche Expand Development Program for MEM 3454 in Schizophrenia 3Memory Pharmaceuticals & Roche Expand Development Program for MEM 3454 in Schizophrenia 4Focus Diagnostics Launches Laboratory Test for Chikungunya Virus 2Focus Diagnostics Launches Laboratory Test for Chikungunya Virus 3Focus Diagnostics Launches Laboratory Test for Chikungunya Virus 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: