Navigation Links
UCSF team discovers new way to predict breast cancer survival and enhance effectiveness of treatment
Date:4/2/2011

A team of researchers at the University of California, San Francisco has discovered a new way to predict breast cancer survival based on an "immune profile" the relative levels of three types of immune cells within a tumor. Knowing a patient's profile may one day help guide treatment.

Moreover, the UCSF team showed that they could use drugs to alter this immune profile in mice. Giving these drugs to mice, in combination with chemotherapy, significantly slowed tumor growth, blocked metastasis and helped mice live longer, suggesting that the approach may work in people.

According to UCSF Department of Pathology Professor Lisa Coussens, PhD, who led the research, a clinical trial for women with advanced breast cancer based on this discovery should begin enrolling patients at the UCSF Helen Diller Family Comprehensive Cancer Center and two collaborating institutions later this year.

"If our work translates into the clinic," said Coussens, "it may improve the effectiveness of chemotherapy in the treatment of certain cancers."

A research article describing this discovery appears in the inaugural issue of the journal Cancer Discovery today. Coussens also is presenting the results at the American Association for Cancer Research meeting in Orlando, FL this week.

WHY ISN'T THE BODY IMMUNE TO CANCER?

Breast cancer continues to be a major health problem in the United States, and the National Cancer Institute estimates more than 200,000 Americans are diagnosed with the disease every year. It is the second leading cause of cancer death among American women, claiming more than 40,000 lives in 2009 alone.

Basic cancer research at UCSF, and elsewhere across the country, seeks to address this problem by asking fundamental questions about the disease. A few years ago, Coussens and her colleagues were doing just that, wondering: Why isn't the body more immune to cancer?

Scientists have known for years
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. OHSU Doernbecher discovers new approach to drug resistance in aggressive childhood cancer
2. MU chemist discovers shortcut for processing drugs
3. deCODE discovers genetic markers that improve the power of PSA testing for detecting prostate cancer
4. UT professor defines play, discovers even turtles need recess
5. Research discovers how the deaf have super vision
6. Colorado researcher discovers mechanism for changing adult cells into stem-like cells
7. Researcher at Childrens Hospital LA discovers way to overcome radiation resistance in leukemia
8. TGen-Mayo Clinic study discovers role of DNA methylation in multiple myeloma blood cancer
9. Virginia Tech professor discovers new TB pathogen
10. UCSF-led team discovers familial link in rare childhood leukemia
11. UR discovers new way to boost vaccines, seeks patent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/3/2015)... (PRWEB) , ... August 03, 2015 , ... ... Health notes that while an overwhelming number of Hispanics believe people can ... The overwhelming 70 percent of participants queried said making diet changes was important. ...
(Date:8/3/2015)... (PRWEB) , ... August 03, ... ... bodybuilding and fitness site and the largest online retailer of nutritional supplements, ... BPI Sports is up for 11 awards in the following categories:, ...
(Date:8/3/2015)... Beach, CA (PRWEB) , ... August 03, 2015 ... ... individuals suffering from ALS and amputation , AUGUST 3, 2015 – Since winning ... category in March 2015, Not Impossible – an organization whose mission is to ...
(Date:8/3/2015)... NC (PRWEB) , ... August 03, 2015 , ... The ... by experience. Learning from her grandmother’s side at a young age, Nasreen Zereshki was ... Zereshki has decided to share her cookbook Recipes from My Persian Kitchen with the ...
(Date:8/3/2015)... FL (PRWEB) , ... August 03, 2015 , ... AxoGen, ... nerve injuries, is scheduled to present at the Wedbush Healthcare Conference on Wednesday, August ... A live webcast and subsequent archived replay of the Company’s presentation may be accessed ...
Breaking Medicine News(10 mins):Health News:Hispanics More Likely to Struggle with Misinformation About Diabetes 2Health News:Hispanics More Likely to Struggle with Misinformation About Diabetes 3Health News:Hispanics More Likely to Struggle with Misinformation About Diabetes 4Health News:BPI Sports is Nominated for 11 Different 2015 Bodybuilding.com Supplement Awards 2Health News:BPI Sports is Nominated for 11 Different 2015 Bodybuilding.com Supplement Awards 3Health News:Not Impossible Earns Top Awards for Technologies Benefiting Humanity 2Health News:Not Impossible Earns Top Awards for Technologies Benefiting Humanity 3Health News:Not Impossible Earns Top Awards for Technologies Benefiting Humanity 4Health News:Persian Cuisine: Colorful and Extremely Healthy 2Health News:AxoGen, Inc. to Present at the Wedbush Healthcare Conference 2
... 20 CHF,International has been selected as the ... Fund) new Principal Recipient (PR) for,HIV/AIDS prevention, treatment ... awarded an HIV proposal in Round 3 programming., ... years, CHF will be directly responsible for,managing Honduras, ...
... How familiar are you,with the health of your family ... festivity of the Thanksgiving holiday, taking a good look ... That,s why Acting Surgeon General Steven K. Galson, ... Family History Day.,He encourages everyone to use the occasion ...
... System Sets ... Space-Saving Standard, WARRENDALE, ... EP Mobile MR Injection System today, MEDRAD once again,addresses the ... with market-leading injector technology suited for,small spaces. (Logo: ...
... ... ... Subspecialty,Radiology (F&S) has added 31 subspecialty radiologists to support the,growing ... industry,s largest subspecialty teleradiology network. F&S,radiologists are musculoskeletal, body, cardiac, ...
... day the Los,Angeles Times reported that cancer survivors could ... care proposals, smooth,talking Mitt Romney is slated to discuss ... report, cancer survivors "could not be,sure of getting coverage ... government or job-related plan and had to seek insurance ...
... Irvine, Calif., Nov. 20 2007 Vase or face" When presented ... a vase or the faces of two people, what we observe ... brains. , In this example, whether you see faces ... since the image always stays exactly the same, said John Serences, ...
Cached Medicine News:Health News:CHF International Named Global Fund Principal Recipient in Honduras 2Health News:Acting Surgeon General Encourages Americans to Know Their Health History During Fourth Annual Family History Day 2Health News:Acting Surgeon General Encourages Americans to Know Their Health History During Fourth Annual Family History Day 3Health News:MEDRAD Mobile MR Injector Meets Challenges of MR Trailers 2Health News:Franklin & Seidelmann Adds 31 Subspecialty Radiologists to Support Growing Demand for Subspecialty Expertise 2Health News:Franklin & Seidelmann Adds 31 Subspecialty Radiologists to Support Growing Demand for Subspecialty Expertise 3Health News:Franklin & Seidelmann Adds 31 Subspecialty Radiologists to Support Growing Demand for Subspecialty Expertise 4Health News:Franklin & Seidelmann Adds 31 Subspecialty Radiologists to Support Growing Demand for Subspecialty Expertise 5Health News:Franklin & Seidelmann Adds 31 Subspecialty Radiologists to Support Growing Demand for Subspecialty Expertise 6Health News:Franklin & Seidelmann Adds 31 Subspecialty Radiologists to Support Growing Demand for Subspecialty Expertise 7Health News:Franklin & Seidelmann Adds 31 Subspecialty Radiologists to Support Growing Demand for Subspecialty Expertise 8Health News:Mitt's Millions Can't Buy Iowans Health Care Reform 2Health News:Scientists uncover how the brain controls what the eyes see 2
(Date:7/31/2015)... 31, 2015  In today,s ever-changing marketplace, call centers ... mobile, increasingly connected, and increasingly impatient with slow service. ... interaction channels and tools is driving call centers to ... According to research by benchmarking firm, Best ... segment in a call center study realize the impact ...
(Date:7/31/2015)... 31, 2015 More than 1,500 substance abuse ... convene in Indianapolis Aug. 2-6 ... Mid-Year Training Institute . The week-long training, held at ... one of our nation,s biggest public health challenges – ... Institute is a one-of-a-kind intensive training opportunity, offering more ...
(Date:7/31/2015)... RnRMarketResearch.com adds Syringes and ... that provides an overview of syringes and needles ... in-house databases, secondary and primary research. ... pipeline spread across 124 pages, talking about 13 ... 5 figures is now available at http://www.rnrmarketresearch.com/syringes-and-needles-pipeline-review-2015-market-report.html ...
Breaking Medicine Technology:Best Practices in Building World-Class Consumer & Over-the-Counter Call Centers 2Community Leaders From Across The Country Head To Indianapolis For CADCA 2015 Mid-Year Training Institute Aug. 2-6 2Syringes and Needles Market Products Pipeline Review 2015 Report 2Syringes and Needles Market Products Pipeline Review 2015 Report 3Syringes and Needles Market Products Pipeline Review 2015 Report 4Syringes and Needles Market Products Pipeline Review 2015 Report 5
... July 28, 2011 /PRNewswire-Asia/ -- China Kanghui Holdings (NYSE: ... developer, manufacturer and marketer of orthopedic implants in China, today ... financial results on August 16, 2011, before the market opens. ... a.m. ET on August 16, 2011 to discuss second quarter ...
... Soligenix, Inc. (Soligenix or the Company) (OTC BB: ... amendment of its North American licensing partnership with Sigma ... development and commercialization of orBec® (oral beclomethasone dipropionate or ... part of the amended agreement, Sigma - Tau has ...
Cached Medicine Technology:China Kanghui Holdings to Report Second Quarter 2011 Financial Results on August 16, 2011 2Soligenix Announces Expansion of Partnership With Sigma-Tau Pharmaceuticals for orBec® in Europe 2Soligenix Announces Expansion of Partnership With Sigma-Tau Pharmaceuticals for orBec® in Europe 3Soligenix Announces Expansion of Partnership With Sigma-Tau Pharmaceuticals for orBec® in Europe 4Soligenix Announces Expansion of Partnership With Sigma-Tau Pharmaceuticals for orBec® in Europe 5Soligenix Announces Expansion of Partnership With Sigma-Tau Pharmaceuticals for orBec® in Europe 6Soligenix Announces Expansion of Partnership With Sigma-Tau Pharmaceuticals for orBec® in Europe 7Soligenix Announces Expansion of Partnership With Sigma-Tau Pharmaceuticals for orBec® in Europe 8
Ideal for nucleus manipulation during phacoemulsification. Also used for manipulating and rotating IOLs within the anterior chamber. Round knurled handle...
Short, narrow paddle angled 45 degree inserts through the side port stab incision and is ideal for effective manipulation of the lens during anterior chamber phacoemulsification....
Nucleus divider with 1.25 mm tip and blade offset at a 60 degree angle is ideal for performing the "Phaco Chop" technique. Round knurled handle. Manufactured in titanium....
#2 10 mm hook. Flat serrated handle with polished finish. Overall length: 5.5 inches....
Medicine Products: