Navigation Links
UCSF study shows greater impact of chemotherapy on fertility
Date:8/25/2011

nses after treatment), early menopause (menopause before 45 years old), and infertility (failed conception).

A total of 1,041 women diagnosed with one of five targeted cancers between the ages of 18 and 40 years old responded, and 620 reported having been treated with only chemotherapy. The five cancer types leukemia, Hodgkin's disease, non-Hodgkin lymphoma, breast cancer and gastrointestinal cancers were chosen because they are common non-gynecologic cancer groups that can be treated with systemic chemotherapy.

Key findings include:

  • The percentage of women reporting acute ovarian failure was 8 percent, 10 percent, 9 percent and 5 percent for Hodgkin's disease, non-Hodgkin lymphoma, breast cancer, and gastrointestinal cancers respectively. Acute ovarian failure increased significantly with age at diagnosis.
  • In women without acute ovarian failure, the incidence of infertility increased significantly with age at diagnosis. For instance, the proportion of infertile women with Hodgkin's disease was 18 percent at 20 years old and 57 percent at 35 years old.
  • The estimated probability of early menopause increased significantly with younger age at diagnosis. For example, using age as a predictor of early menopause in non-Hodgkin lymphoma, 56 percent of women 20 years old at diagnosis may experience menopause early, compared to 16 percent of those who were 35 years old at diagnosis.

Approximately 120,000 women younger than age 50 develop cancer each year in the United States, according to statistics from the 2006 Surveillance, Epidemiology, and End Results (SEER), and several studies show that loss of reproductive potential after cancer treatment can negatively impact quality of life in young survivors.

While 7 percent of women across the United States report 12-month infertility according to the researchers, the rates of infertility in young cancer patients are unknown.

"We noted proportions o
'/>"/>

Contact: Karin Rush-Monroe
karin.rush-monroe@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Realistic Activity Goals Seem to Ease Arthritis Pain, Study Finds
2. New study benchmarks current critical care practices in the United States
3. Bubble Boy Kids Living Normally After Gene Therapy: Study
4. Study of HIV increase in Pakistan could benefit other research
5. Unintended Pregnancies Rising Among Poorer U.S. Women: Study
6. Study: 85 percent of homeless people have chronic health conditions
7. Nurses at Risk for Accidental Exposure to Chemo Drugs: Study
8. Boys Mature Sexually Earlier Than Ever Before: Study
9. Women With Heart Failure Treated as Well as Men: Study
10. Injectable Psoriasis Drugs May Not Hike Heart Risks: Study
11. Mental Illness Affects Women, Men Differently, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCSF study shows greater impact of chemotherapy on fertility
(Date:4/23/2014)... Washington State University Spokane have developed a new ... nod off behind the wheel. , Their recently ... are more variable in drowsy driversand offers an ... video-based driver drowsiness detection systems. , Van Dongen"Video-based ... car is drifting out of its lane are ...
(Date:4/23/2014)... - Purdue University researchers have developed a way to ... by using tiny gold particles with tails of synthetic ... agricultural and biological engineering, used gold nanoparticles to target ... BRCA1 messenger RNA splice variants, which can indicate the ... these mRNA splice variants in a cell can be ...
(Date:4/23/2014)... computer program could help doctors predict which patients might ... , The program, which assesses brain scans using ... security and passport control, has been developed by researchers ... funded by the Wellcome Trust, which used the software ... , Stroke affects over 15 million people each ...
(Date:4/23/2014)... country as wealthy as the United States, it may come ... have access to adequate food due to lack of money ... Recent research at the University of Illinois using data from ... the seniors who are dealing with hunger are also facing ... percent of Americans over age 60 faced the threat of ...
(Date:4/23/2014)... journal Oncotarget , explored tumour heterogeneity ... own DNA signatures within the same cancer. Such ... targeted treatment strategies. , Firstly they confirmed the ... the KRAS or BRAF mutation. Secondly, they found ... mutation have that specific mutation present uniformly throughout ...
Breaking Medicine News(10 mins):Health News:WSU innovation improves drowsy driver detection 2Health News:Gold nanoparticles help target, quantify breast cancer segments in a living cell 2Health News:Airport security-style technology could help doctors decide on stroke treatment 2Health News:Airport security-style technology could help doctors decide on stroke treatment 3Health News:More Americans in their golden years are going hungry 2Health News:Non-uniform genetic mutations identified in lung cancers could lead to targeted treatment 2
... older adults with one of two classes of available drugs ... yearly flu shots are likely a better bet. // ... caring for older adults with the flu or a flu-like ... for flu before treatment with an anti-flu drug, and treating ...
... new study finds whole grains, fruits and vegetables will decrease ... dying. However, the study also reports these foods do not ... Dietary Guidelines for Americans include choosing a variety of fruits ... especially whole grains. While at least five fruits and vegetables ...
... lung cancer before it's in a more advanced stage is ... //can detect early lung cancer, researchers wanted to determine if ... researchers who wanted to look at the cost-effectiveness of a ... part of the Early Lung Cancer Action Project (ELCAP) that ...
... the drug dalteparin is beneficial for diabetic patients with severe ... for diabetic patients and are one of the most expensive ... limb of the diabetic patient. A new study led by ... of the drug dalteparin on foot ulcers in diabetic patients. ...
... they've developed a new way to treat certain kinds ... that emits far more high-energy radioactivity than current radio-isotopes ... tumor cells invade bone marrow. For many years, doctors ... with bone metastases. ,The radio-isotopes ease pain by ...
... vascular dementia find it can help treat the cognitive ... or VaD -- is usually associated with cardiovascular disease. ... of dementia are attributed to VaD. Unlike Alzheimer’s disease, ... time, VaD often strikes quickly, such as after a ...
Cached Medicine News:
(Date:1/15/2014)... , Jan. 15, 2014 Most osteoporosis patients want ... a recent online survey* sponsored by Mission Pharmacal Company. ... National Osteoporosis Foundation online support community, revealed that 74 ... that comes in a form other than a pill ...
(Date:1/15/2014)...  Novation, the leading health care supply chain expertise, analytics ... (VAR) national contracts that expand its portfolio to provide ... costs. These include manufacturer product and service agreements, as ... ongoing IT consulting support. New Novation ...
(Date:1/15/2014)... 15, 2014  Humberto C. Antunes,  Galderma  worldwide CEO, will ... Journal of Drugs in Dermatology (JDD) at ... The event is January 17-20, 2014, at the Omni Orlando Resort ... The ODAC is a distinguished event that ...
Breaking Medicine Technology:Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 2Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4
... 16, 2011 /PRNewswire-Asia-FirstCall/ -- China Medical ... CMED ), a leading China-based ... its unaudited financial results for the ... 2011 ("1Q FY2011") today.1 Q ...
... More than a decade of targeted Muscular Dystrophy Association-funded ... support of the MDA Labor Day Telethon and thousands ... providing financial assistance for the start of the first ... pharmacokinetics clinical trial of an exon-51 skipping drug, eteplirsen, ...
Cached Medicine Technology:China Medical Technologies Reports First Fiscal Quarter Financial Results 2China Medical Technologies Reports First Fiscal Quarter Financial Results 3China Medical Technologies Reports First Fiscal Quarter Financial Results 4China Medical Technologies Reports First Fiscal Quarter Financial Results 5China Medical Technologies Reports First Fiscal Quarter Financial Results 6China Medical Technologies Reports First Fiscal Quarter Financial Results 7China Medical Technologies Reports First Fiscal Quarter Financial Results 8China Medical Technologies Reports First Fiscal Quarter Financial Results 9China Medical Technologies Reports First Fiscal Quarter Financial Results 10China Medical Technologies Reports First Fiscal Quarter Financial Results 11China Medical Technologies Reports First Fiscal Quarter Financial Results 12China Medical Technologies Reports First Fiscal Quarter Financial Results 13China Medical Technologies Reports First Fiscal Quarter Financial Results 14China Medical Technologies Reports First Fiscal Quarter Financial Results 15China Medical Technologies Reports First Fiscal Quarter Financial Results 16China Medical Technologies Reports First Fiscal Quarter Financial Results 17China Medical Technologies Reports First Fiscal Quarter Financial Results 18China Medical Technologies Reports First Fiscal Quarter Financial Results 19MDA Collaborates with AVI BioPharma on First Phase 2 Placebo-Controlled Clinical Trial of Exon-51 Skipping Drug as Potential Therapy for Duchenne Muscular Dystrophy 2MDA Collaborates with AVI BioPharma on First Phase 2 Placebo-Controlled Clinical Trial of Exon-51 Skipping Drug as Potential Therapy for Duchenne Muscular Dystrophy 3MDA Collaborates with AVI BioPharma on First Phase 2 Placebo-Controlled Clinical Trial of Exon-51 Skipping Drug as Potential Therapy for Duchenne Muscular Dystrophy 4
... Direct to High Res SSP kits provide high resolution ... Locus specific typing on a single tray reduces QC ... from genomic DNA to high resolution results, no need ... with a single tray , Unique reaction pattern for ...
... the storage of blood plasma in full ... attention to operating temperatures and performance means ... Standard freezer you will minimise bag cracking ... temperature an additional benefit is reduced thawing ...
Designed to complement Blood Bank Refrigerators, it freezers offer outstanding features, including programmable defrost times....
Plasma Blast Chest Freezer -50C - 8098/8091 maintains a -50C (-58F) temperature to rapidly freeze single donor, apheresed, and fresh frozen plasma. Rapid freezing also preserves Factor VIII. Full loa...
Medicine Products: