Navigation Links
UCSF study identifies weakness in heart attack therapy
Date:9/20/2011

A UCSF study holds clues to why an emerging clinical trials option for heart attack patients has not been as successful as anticipated. Treatment of human hearts with bone marrow cells has led to limited to no success in improving their heart function even though a similar method has been much more effective in rodents.

Scientists didn't have a plausible research-based answer until now, according to the UCSF researchers. In a paper published this month in the scientific journal Science Translational Medicine, researchers offer an explanation of why a gap exists been the success of human trials and rodent experiments.

Researchers use bone marrow from young, healthy donor rodents to treat mice that had heart attacks. However in humans, bone marrow cells came from the patients themselvestypically olderafter they suffered heart attacks.

"It's very important to consider the disease, whenever you think about treatments that involve returning cells into the same person from whom they were taken," said the paper's senior author Matt Springer, PhD, associate professor of medicine in the UCSF Division of Cardiology and UCSF Cardiovascular Research Institute. "The very disease you're trying to treat might actually cause a problem for those cells, and that seems to be the case here.

A heart attack occurs about every 20 seconds in the United States with a heart attack death occurring approximately every minute, according to the Centers for Disease Control and Prevention (CDC). That translates to about 500,000 deaths from 1.5 million heart attacks. It is the leading cause of death for men and women in America.

"Heart attacks are very complicated, and are hard to treat even with pharmacology and interventional therapies," said Xiaoyin Wang, MD, lead author, and an associate research specialist at the UCSF Cardiovascular Research Institute. "It's difficult
'/>"/>

Contact: Leland Kim
leland.kim@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

0

GOOD

Page: 1 2 3

Related medicine news :

1. Diverticulitis Surgery More Dangerous for Older Black Patients: Study
2. ADHD Drug Delays Puberty in Male Monkeys, Study Finds
3. U.S. Flu Shot Policy Shields More Kids Than Canadas Program, Study Finds
4. Brains of Obese May Crave High-Calorie Foods More: Study
5. Study: Overweight older women have less leg strength, power
6. Lack of Sleep Hurts Kids Academic Performance: Study
7. Study suggests possible link between two Type 2 diabetes drugs and pancreatic cancer
8. Major grant awarded for HIV prevention study in Africa
9. Number of children poisoned by medication rising dramatically, study says
10. Study update: Cancer information on Wikipedia is accurate, but not very readable
11. Wikipedia Accurate on Cancer Facts, But Hard to Read: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCSF study identifies weakness in heart attack therapy
(Date:5/21/2013)... 21, 2013 Representatives with Hammerhead Bicycles announced ... success that the company has achieved its overall goal of ... one was to move Hammerhead Bicycles from a house brand ... Scott Robertson. , Robertson explained that the bike shop will ... exclusively focus on all things 29er and 650b. ...
(Date:5/21/2013)... MAY 21, 2013 Three major Ohio universities and ... Foundation to establish a new collaborative research program aimed ... The March of Dimes intends to invest $10 million ... March of Dimes Prematurity Research Center -- Ohio Collaborative ... Howse, President of the March of Dimes. "This new ...
(Date:5/21/2013)... Atlanta, GA (PRWEB) May 21, 2013 ... Care, ScripNet and Procura Management, today announced that ... Award at Catamaran’s client advisory meeting. Conferred ... has partnered with Catamaran to create cutting edge ... This year, Healthcare Solutions was recognized for its ...
(Date:5/21/2013)... 2013 A plastic surgery Internet ... plastic surgery SEO services following an Internet survey. ... name the “Best Plastic Surgery SEO Services”. , ... was predictable. Well-known in the plastic surgery Internet ... than any other selection based on superior client ...
(Date:5/21/2013)... (PRWEB) May 21, 2013 Nearly 40 ... out of an award trip in Los Cabos, Mexico, Feb. ... “day house” for the elderly. , The facility serves meals ... of San Jose del Cabo, Mexico. , Platinum Vice President, ... while reflecting on the company’s history. , “Platinum got its ...
Breaking Medicine News(10 mins):Health News:Hammerhead Bicycles Now a Standalone Brand 2Health News:New multi-million dollar research center aims to solve the mystery of premature birth 2Health News:New multi-million dollar research center aims to solve the mystery of premature birth 3Health News:Healthcare Solutions Receives Innovation Award From Catamaran 2Health News:JD Media Surge's CosmeticSurgeonsOnline.com Voted #1 Source for Plastic Surgery SEO 2Health News:Platinum Supplemental Insurance Gives Back at Casa De Dia, Mexico 2Health News:Platinum Supplemental Insurance Gives Back at Casa De Dia, Mexico 3
... preventable, treatable diseases around,the world, Statement by ... TOYAKO, Japan, July 8 "The worldwide,pharmaceutical ... and,the Drugs for Neglected Diseases initiative (DNDi) in ... neglected diseases as a global health threat,and a ...
... 8 An economist examining the,proposed merger of ... the combined companies would have a market share ... to testimony presented to the,Pennsylvania Insurance Department today ... of CRA International, the proposed merger,would result in ...
... disorder is one of the most complex and challenging ... associated with considerable acute and longterm treatment needs and ... times of tremendous social burden for both the individual ... episodic, yet lifelong and clinically severe mood disorder. The ...
... tendon rupture, agency says , , TUESDAY, July 8 (HealthDay ... carry a black box warning alerting physicians to the ... their use, the U.S. Food and Drug Administration said ... 60; in kidney, heart and lung transplant recipients; and ...
... At 12:00 noon on July 8, 2008, J.,Douglas ... P.C.,filed the first drug product liability action in ... former Governor Engler,s grant of immunity,to drug manufacturers., ... was filed in the United,States District Court, Eastern ...
... the most important single factor predisposing to suicide, ... suicide are known to have suffered from depression. ... even after a suicide attempt. Antidepressive drugs represent ... their role has become somewhat controversial over the ...
Cached Medicine News:Health News:Global Health Progress Joins WHO and DNDi to Call For Increased Commitments to Fighting Neglected Tropical Diseases 2Health News:Economist Finds Highmark/IBC Merger Would Result in 70 Percent Share in Pennsylvania, Far Higher Than Initial Reports 2Health News:The ECNP consensus statement on bipolar depression 2Health News:FDA Mandates Black Box Warning for Some Antibiotics 2Health News:National Class Action Filed Against Manufacturer of Digitek(R) (Prescription Drug) in Federal Court in Michigan 2
(Date:5/21/2013)... 2013 iHealth Lab Inc., a pioneer ... healthcare products and a powerful integrated mobile app ... of two new fitness products to its existing ... the Wireless Pulse Oximeter and Wireless Activity and ... iHealth Lab is also excited ...
(Date:5/21/2013)... , May 21, 2013  Lehigh Valley Health Network ... TM devices, adding to its existing arsenal of ... taking up residence within the network, LVHN is now ... to proactively combat superbugs and provide the best possible ... Room Ultraviolet Disinfector, TRU-D – the signature product of ...
(Date:5/21/2013)... 21, 2013  Healthcare organizations expanding into emerging markets ... , India and ... no shortcuts.  This is proving particularly challenging, considering the ... must change the dialogue around BRIC, as it is ... and building regional partnerships to build a sustainable business. ...
Breaking Medicine Technology:iHealth Lab adds new products and partners to mobile personal healthcare offering 2iHealth Lab adds new products and partners to mobile personal healthcare offering 3Lehigh Valley Expands Fleet of Superbug-Slaying Robots 2Lehigh Valley Expands Fleet of Superbug-Slaying Robots 3Frost & Sullivan: BRIC is Not Delivering Promises of High Growth in Healthcare Markets 2Frost & Sullivan: BRIC is Not Delivering Promises of High Growth in Healthcare Markets 3Frost & Sullivan: BRIC is Not Delivering Promises of High Growth in Healthcare Markets 4
... Va., Aug. 30, 2011 Star Scientific, Inc. (NASDAQ: ... is pleased to initiate the launch today of Anatabloc™, ... immune system in maintaining healthy levels of inflammation.  Anatabloc™, ... being launched via a dedicated website ( www.anatabloc.com ) ...
... 2011 Bench International, a global, milestone-based, performance-driven ... sciences industry, recently opened new offices in Geneva ... strategy. The offices are strategically placed to serve ... aligned with Bench,s European headquarters in London to ...
Cached Medicine Technology:Star Scientific Launches Anatabloc™ Dietary Supplement 2Star Scientific Launches Anatabloc™ Dietary Supplement 3Star Scientific Launches Anatabloc™ Dietary Supplement 4Star Scientific Launches Anatabloc™ Dietary Supplement 5Bench International Expands Presence in Europe with Opening of Offices in Switzerland 2
Hudson Drill hand drill....
Hudson Downs hand drill....
Hudson Brace, snap lock chuck....
Sighting and visualization system of the digital operating suite. The platform that links navigation, and intra-operative imaging to form the ultimate surgical workstation....
Medicine Products: