Navigation Links
UCSF launches groundbreaking online registry to drive brain disease research
Date:4/8/2014

A new online project led by researchers at UC San Francisco promises to dramatically cut the time and cost of conducting clinical trials for brain diseases, while also helping scientists analyze and track the brain functions of thousands of volunteers over time.

With easy online registration, the Brain Health Registry is designed to create a ready pool of research subjects for studies on neurological diseases, such as Alzheimer's and Parkinson's, as well as depression, post-traumatic stress disorder and many other brain ailments. About one third of the cost of running a clinical trial comes from having to recruit patients, and many trials fail or are delayed because of it.

The Brain Health Registry is the first neuroscience project to use the Internet on such a scale to advance clinical research, according to Michael Weiner, MD, founder and principal investigator of the initiative and a professor of radiology, biomedical engineering, medicine, psychiatry and neurology at UCSF. One of his roles is serving as principal investigator of the Alzheimer's Disease Neuroimaging Initiative, the largest observational study of Alzheimer's.

"This registry is an innovative 21st century approach to science with tremendous potential," Weiner said. "The greatest obstacles to finding a cure for Alzheimer's and other brain disorders are the cost and time involved in clinical trials. This project aims to cut both and greatly accelerate the search for cures."

Leading funders for the project include the Rosenberg Alzheimer's Project, the Ray and Dagmar Dolby Family Fund and Kevin and Connie Shanahan. The initial focus will be on the San Francisco Bay Area, and the goal is to recruit 100,000 people by the end of 2017. Nearly 2,000 people already signed up during the online Registry's beta phase.

Volunteers will provide a brief personal history and take online neuropsychological tests in an online game format. The games give the Brain Health Registry scientific team a snapshot of the participant's brain function. The data collected will help scientists study brains as they age, identify markers for diseases, develop better diagnostic tools to stop disease before it develops and increase the ready pool of pre-qualified clinical trial participants.

A select number of volunteers will be asked by researchers to do more, such as providing saliva or blood samples, or participating in clinical trials to test potential cures. Volunteers can participate as little or as much as they like. All information will be gathered in accordance with federal privacy laws under the Health Insurance Portability and Accountability Act (HIPAA), as well as the highest standards of medical ethics.

"For those of us who know people suffering from Parkinson's, Alzheimer's, PTSD and other brain disorders, this is a way we can be involved in the search for a cure," said Douglas Rosenberg, of the Rosenberg Alzheimer's Project, which is helping to fund the project. "We've worked to make the process very easy and very fulfilling for our volunteers."

Recruiting costs are a large part of the expense of conducting clinical trials, which, in turn, help drive up the cost of developing new drugs. Early stage trials, which focus on safety and preliminary efficacy, can cost tens of millions of dollars. Late stage trials, which involve hundreds, if not thousands, of people and focus on efficacy, can cost hundreds of millions. Trials at both stages can drag on for years, largely because recruitment is such a big challenge.

"Dr. Weiner is putting together a Bay Area 'ready for trials' group that will bring more patients forward for therapies," said Bruce Miller, the A.W. and Mary Margaret Clausen Distinguished Professor in Neurology at UCSF and director of the Memory and Aging Center. "A central registry could speed this process up dramatically and save a lot of money."

The Brain Health Registry has partnered with Lumosity, the San Francisco-based brain training and neuroscience research company. Lumosity is helping recruit members for the Brain Health Registry and has also provided a battery of online assessments as part of the brain performance tests. The Brain Health Registry is also collaborating with healthcare and product leader Johnson & Johnson Innovation and Cogstate, the Australian company known for its computer-based cognitive assessment tools.

"The Brain Health Registry is aligned with our research goals and has the potential to transform clinical trial recruitment for brain conditions and open up new opportunities for research, said Michael Scanlon, Chief Scientific Officer of Lumosity. "We are excited to partner with UCSF and the Brain Health Registry to advance neuroscience research and gain a better understanding of the human brain."


'/>"/>

Contact: Laura Kurtzman
laura.kurtzman@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Related medicine news :

1. Elsevier launches open access journal: Internet Interventions
2. Childhood adversity launches lifelong relationship and health disadvantage for black men
3. UT Southwestern launches Center for Patient-Centered Outcomes Research
4. Population Council launches study testing interventions to improve girls lives in Kenya
5. Regina Alcohol & Drug Rehab Launches Program to Help Adults and Adolescents Stop Addiction to Bath Salts
6. PreDiabetes Centers Launches Two New Supplements at The PreD Store
7. Silvertip Software Re-Launches RoomTime Room-Scheduling App; Early Adopter Program Expires Soon, Limited Space Remains
8. Lakeview Health Launches New Website and ‘True North’ Campaign to Reimagine Addiction Treatment
9. Blush Launches New Online Life-Coaching Website
10. Branding & Marketing Agency Trajectory Creates and Launches a Responsive Website for AHAM: CoolEnergySavings.org
11. TGA Premier Junior Golf Launches School Based Activation and Business Model in Canada
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/25/2017)... ... 25, 2017 , ... Splashtop Inc. , the worldwide ... new addition to the Mirroring360 product family combines device screen mirroring with screen ... enables educators, business professionals and individuals to stream or mirror app screens, music, ...
(Date:4/25/2017)... , ... April 25, 2017 , ... ... attempts to compare student test score performance for the 2015-16 school year across ... state’s voucher programs. Though it highlights important patterns in student test score performance, ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... ... the way in unveiling cutting-edge birth defects research related to Zika virus during ... the world’s premier society for this important science. , The Teratology ...
(Date:4/25/2017)... ... ... Emergency Physician and Distinguished Professor of Emergency Medicine Bentley Bobrow will be featured ... publish in summer 2017. , Dr. Bobrow, MD, FACEP, FAHA, is an Emergency ... He also serves as Medical Director for the Bureau of Emergency Medical Services and ...
(Date:4/24/2017)... ... 2017 , ... LG CNS Healthcare Solutions debuted the next ... Telehealth 2.0, the American Telemedicine Association’s national conference. , BYOD has been added ... pre-programmed tablet in a remarkably easy-to-use kit for patients. “BYOD is the next ...
Breaking Medicine News(10 mins):
(Date:4/24/2017)... , April 24, 2017 SW Safety ... protection, and comfort, announces the release of the latest ... This most recent example of leading edge nitrile glove ... pattern for 200% more tactile grip on wet and ... and durability. With TracTek and a suite of other ...
(Date:4/20/2017)... 2017  Vivify Health, the pioneer and market leader ... a very significant patent for the advancement of healthcare ... via digital health.  This landmark patent provides the company ... secures Vivify,s position as the leader in remote care.  ... first company to apply consumer mobile devices, wireless biometrics, ...
(Date:4/20/2017)... 20, 2017 Research and Markets has announced ... Driven by Rapidly Expanding Injectables Market and Increasing Usage of Complex ... ... technologies will rise from USD 20 Billion in 2015 to around ... Delivery Technologies - Innovation Driven by Rapidly Expanding Injectables Market and ...
Breaking Medicine Technology: