Navigation Links
UCSF Team Closer to Creating Safe Embryonic-Like Stem Cells
Date:4/13/2009

ult cells, such as those of the heart, lung and brain. These cells could then be transplanted into patients, without the fear of rejection.

The study, reported in the April 12, 2009 advanced online edition of the journal "Nature Biotechnology" and scheduled for the May 8, 2009 print issue, used a combination of microRNAs and retrovirus-introduced genes to transform fibroblast cells -- found throughout the body of mice and humans -- into pluripotent cells.

The current finding comes on the heels of a study published by the group in the December 2008 print edition of "Nature Genetics" that showed that microRNAs, which can be synthesized in the lab, encouraged embryonic stem cells to self-replicate, a finding that has implications for replicating stem cells in the culture dish and exploring stem cells' role in cancers.

Previous methods for creating embryonic stem cell-like cells have relied on the introduction of DNA that encodes four transcription factors, proteins that play a role in the production of genes. The limitation of this method is that three of the four genes that code for these transcription factors -- oct4, klf4 and c-myc - are oncogenes, meaning they promote the uncontrolled cell growth characteristic of cancer.

In the current study, led by Robert Judson, a graduate student in the Blelloch lab, the scientists induced pluripotency using a combination of infection and transfection. The infection involved introducing three viruses, each containing a transcription factor known to induce pluripotency. The transcription factor for c-myc was not included. The transfection involved a simple process in which the tiny microRNA molecules were mixed with a lipid, allowing them to pass through the cell membrane. By labeling the fibroblast cells, they showed that the treated cells could be incorporated into a mouse embryo and become every cell type in the adult animal -- including germline cells that would prod
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. UCSF team closer to creating safe embryonic-like stem cells
2. Yale Plans Closer Look at Exercise and Cancer
3. University of Washington scientists one step closer to stopping bone loss during spaceflight
4. Scientists closer to understanding how to control high blood sugar
5. Muscular dystrophy mystery solved; Mizzou scientist moves closer to MD solution
6. Video: Pampers Together with Actress Salma Hayek Helps UNICEF Move Closer Toward Goal of Eliminating Deadly Tetanus Through Global One Pack = One Vaccine Campaign
7. Pelosi: SCHIP Vote Brings Us One Step Closer to Providing Health Care for 11 Million Children
8. Health Plans, Employers Take Closer Look at Costs and Expand Disease Management Initiatives in Response to Diabetes Prevalence Increase
9. Molecular therapy for spinal muscular atrophy closer to clinical use
10. Decongestant Exposure Needs Closer Look
11. FDA Takes Closer Look at Wrinkle Treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... September 30, 2014 Catalent Pharma ... advanced delivery technologies and development solutions for drugs, ... full agenda for the 25th Annual CPhI Worldwide ... October 6th to 9th. , Catalent is showcasing ... expansions during the show, including its facilities in ...
(Date:9/30/2014)... Coast Dental and Orthodontics is ... practice, located at 1010 Shaw Avenue in Clovis, CA. ... services , and specialty dental care including orthodontics, endodontics, ... and convenient dental care, our Clovis dentists also strive ... Coast Dental at 559-777-6113 to schedule an appointment. , ...
(Date:9/30/2014)... September 30, 2014 With accolades like the ... Lash Masters II, Hilaree Brand of My Brand Lashes is ... craft and, more importantly, the ability to teach. She leads ... credentials and a great reputation. , With a background in ... a Master of Aesthetics and as an Instructor. She has ...
(Date:9/30/2014)... NY, September 30, 2014Levothyroxine (L-T4), long the standard ... most patients, but some individuals do not regain ... thyroid physiology may help to explain these differences. ... Association on thyroid hormone replacement reviewed the latest ... to determine whether a change to the current ...
(Date:9/30/2014)... Pittsburgh School of Dental Medicine have been awarded a ... Dental and Craniofacial Research, part of the National Institutes ... roots of cleft lip and cleft palate and to ... the Philippines and Pennsylvania. , Orofacial clefts (OFCs), ... that can form when a baby,s mouth doesn,t develop ...
Breaking Medicine News(10 mins):Health News:Catalent Showcases Advanced Technologies and Supply Capabilities at CPhI Worldwide Conference and Exhibition 2Health News:Catalent Showcases Advanced Technologies and Supply Capabilities at CPhI Worldwide Conference and Exhibition 3Health News:Coast Dental Clovis Celebrates Grand Opening 2Health News:Coast Dental Clovis Celebrates Grand Opening 3Health News:My Brand Lashes and Lash Affair By J. Paris Merge to Offer Premium Lash and Brow Products and Certifications 2Health News:My Brand Lashes and Lash Affair By J. Paris Merge to Offer Premium Lash and Brow Products and Certifications 3Health News:New hypothyroidism treatment guidelines from American Thyroid Association 2Health News:Pitt team searches for genetic roots of cleft lip, palate 2
... latest advancement in aspirin delivery ... ... has,rolled out Fasprin(R), a patented, 81 milligram aspirin tablet that,dissolves rapidly ... solution for the millions of Americans who maintain a,daily aspirin routine ...
... Formulas No Better than Generic Store-Brand Infant,Formulas, Says Mayo Clinic ... ... GORDONSVILLE, Va., Nov. 13 The Mayo Clinic, a ... every type of complex illness, now offers an online resource ...
... Awareness and Funds to Fight Homelessness in Los ... LOS ANGELES, Nov. 13 United Way of Greater ... to fight homelessness on,Saturday morning, November 17, 2007, by ... Exposition Park near downtown Los Angeles.,HomeWalk will engage participants ...
... Groundbreaking Meeting Brings Together Cancer Funding Organizations, Advocates, Government ... ... Pharmaceutical Industry, NEW YORK, Nov. 13 Leadership ... and advocacy groups met,on November 1-2 along with experts ...
... of America (GSA) has chosen W. Andrew Achenbaum of ... the Donald P. Kent Award. This distinguished honor is ... the highest standards for professional leadership in gerontology through ... society. , The award presentation will take place ...
... chosen Nancy L. Pedersen of Sweden,s Karolinska Institutet to ... to Gerontology. This prize is given annually to an ... new synthesis and perspective or have yielded original and ... literature. , The award presentation will take place at ...
Cached Medicine News:Health News:New, No-Swallow Fasprin(R) Reduces Problems Associated with Daily Aspirin Regimen 2Health News:Mayo Clinic Supports Store-Brand Infant Formulas 2Health News:United Way of Greater Los Angeles and Fannie Mae Foundation Announce 3000 Marchers for HomeWalk 2007 2Health News:United Way of Greater Los Angeles and Fannie Mae Foundation Announce 3000 Marchers for HomeWalk 2007 3Health News:First-Ever Collaborative Summit on Breast Cancer Research Targets New Partnerships and Collaborative Solutions 2Health News:First-Ever Collaborative Summit on Breast Cancer Research Targets New Partnerships and Collaborative Solutions 3Health News:First-Ever Collaborative Summit on Breast Cancer Research Targets New Partnerships and Collaborative Solutions 4
(Date:9/30/2014)... , Sept. 30, 2014 A study using ... offered a new look at the composition of carotid ... physicians understand and treat the disease, a leading cause ... Baptist Health Lexington between September 2010 and May 2012, ... Journal of the American College of Cardiology (JACC) ...
(Date:9/30/2014)... 30, 2014  HealthLoop® released an app version of ... iOS 8 and allows people to share medical device ... native iOS technologies to enhance the HealthLoop experience for ... with their doctors between visits. "This ... they collect is exciting," says HealthLoop founder Dr. ...
(Date:9/30/2014)...  Georgia-Pacific Professional is a leading provider of ... wide range of away from home applications. Building ... healthcare, including hospitals, long-term care facilities, surgical centers ... healthcare products and solutions to the dental community. ... infection control in the dental office," said ...
Breaking Medicine Technology:New Imaging Tool May Allow Tailoring of Stroke Prevention to Each Patient 2HealthLoop Integrates with Apple's HealthKit Enabling Patients to Share Health Data with Their Doctors Right from their iPhone 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 3
... (Nasdaq: THOR ), a world leader in device-based ... hearts, today announced that it will report its operating results ... 2010 on Thursday, October 28. The company will ... operating activities open to all interested parties at 1:30 p.m., ...
... 22 Bacterin International Holdings, Inc. (OTC Bulletin ... is scheduled to present at the upcoming Singular Research 5th ... 2010 at 3:20p.m.(PT) at the Luxe Hotel Sunset Boulevard, Los ... Bacterin, and John Gandolfo, Bacterin,s chief financial officer, will review ...
Cached Medicine Technology:Thoratec Schedules Third Quarter Conference Call, Webcast 2Bacterin International to Present at Singular Research 5th Annual Best of the Uncovereds Conference 2
Used for the retrieval of stones, stents, or other objects in the urinary tract under direct vision. Retrieval Forceps are designed for use through rigid or flexible endoscopes. Supplied sterile in p...
... technology allows the grasper ... a shorter length and ... the stone. The Unidex ... one-handed operation. Supplied sterile ...
Bugbee Fulgurating...
Fulgurating Electrode, 2 F...
Medicine Products: