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UCSD scientists receive prestigious Hartwell Biomedical Research Awards
Date:4/6/2011

synthetic device. In theory, such a device could provide essential protection to transplanted pancreatic beta-cells in overcoming the autoimmune response that characterizes Type 1 diabetes. If successful, her encapsulated cell technique will not require tissue matching and will not have a requirement for immunosuppression, thus transforming the health and quality of life for diabetic children

Adriana Tremoulet

Kawasaki disease is a rare condition in children that involves inflammation of blood vessels. It is the leading cause of pediatric acquired heart disease in the United States, yet there is no diagnostic test for KD. Current diagnoses are limited to overt clinical signs, such as rash and fever, but these symptoms overlap with other infections and conditions, many of which require no treatment. In up to a third of KD cases, many of the clinical signs are not even present.

Finding single, tell-tale biomarkers for KD has been problematic. Tremoulet proposes to identify a novel panel of biomarkers that will differentiate KD patients from children with benign rash-fever illnesses. If successful, she expects a point of service test for diagnosing KD will be available in every emergency room, pediatric office, and urgent care center in the U.S. within 5-10 years.


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Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

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