Navigation Links
UCSD receives NIH Transformative R01 Award for stimulation of neuron regeneration in the retina
Date:9/29/2010

A research team led by principal investigator Kang Zhang, MD, PhD, professor of ophthalmology at the University of California, San Diego's Shiley Eye Center and director of UCSD's Institute of Genomic Medicine, has been awarded a five year, $4.66 million NIH Transformative Award.

Zhang and co-principal investigators Sheng Ding, PhD, from The Scripps Research Institute, and Thomas Reh, PhD from the University of Washington, received the highest possible scores for their proposal to investigate the regenerative potential of retinal cells. Their long-term goal is to restore visual function lost through diseases such as macular degeneration and retinitis pigmentosa.

"The success of this work could mean a paradigm shift in how retinal disease is treated, and could have broad and profound impact on human disease therapies by utilizing the regenerative power of our own cells," said Zhang.

Some vertebrates, such as goldfish and newts, have a remarkable ability to regenerate a lost limb or eye something it was thought no mammal can do. However, they recently showed proof of principle at a small scale level in mice by turning Muller cells into a type of retinal neuron.

"The human genome is quite similar to that of a newt, but we humans seem to have lost the potential to regenerate our own cells, possibly due to some inhibitory mechanims," Zhang said. "We are seeking small molecule chemicals that can block these inhibitions and consequently unlock humans' regenerative potential."

The Transformative Award program, funded through the Office of the NIH Director and the Common Fund, is intended "to support research that has the potential to transform the way we think about and conduct science, so the recipients represent an elite few with truly bold ideas," according to Francis Collins, Director of the National Institutions of Health.

The researchers are looking at particular kinds of cells called Muller cells,
'/>"/>

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California -- San Diego
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. NACDD Receives Two-Year Grant From Merck & Co., Inc. to Improve Diabetes Education
2. Dr Yaghouti of Global Laser Vision Receives Patient's Choice Award for 2009
3. UT researcher receives $2.4 million to research obesity, high-risk pregnancy
4. BestMassage.com Receives Award for Customer Trust
5. Corporate Wellness Firm Limeade Receives SAS 70 Type II Report
6. Oridion Receives Frost & Sullivan's 2010 Customer Value Enhancement Award
7. Special Olympics Georgia Receives Grant from The Home Depot Foundation
8. NOVAVAX, Inc. Receives NASDAQ Non-Compliance Letter
9. WuXi PharmaTech Receives AAALAC Accreditation for Suzhou Toxicology Facility
10. Verdan Receives Patent on Crystal Deodorant Spray
11. Thomas E. Mower Meets With Dalai Lama; Receives Prestigious Champion Award from Whole Child International
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
UCSD receives NIH Transformative R01 Award for stimulation of neuron regeneration in the retina
(Date:7/12/2014)... The report, "Phthalic Anhydride and Derivatives (Plasticizers, Unsaturated ... Geography – Trends & Forecast to 2018," defines and ... market volume and value. The report also estimates the ... of phthalic anhydride is projected to grow from an ... 2018, with a CAGR of 5.24% from 2013 to ...
(Date:7/12/2014)... Demand Response Management Systems is a crucial peak load ... between energy supply and demand. With the help of ... to increasing pressure on the grid) and replaced by ... appliances and thermostats for load reduction. , DRMS ... with government mandates and benefits for energy efficiency and ...
(Date:7/12/2014)... July 12, 2014 Casinos ... despite rising competition from international and online casinos. Revenue ... over the five years through 2014-15. Greater per capita ... more gaming services. Rises in discretionary income levels have ... money on non-essential items such as casino gambling services. ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Sean Francis, owner of ... out special challenges to his clients. He’s also known for his ... recently found a way to combine the two and is excited ... $2,000 for the Boys and Girls Club. , The funds are ... started on June 23rd. Francis sent out emails and asked his ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 With prom ... dress manufacturer and retailer, is ready to showcase its ... its new collection of evening dresses in its online ... to 67% off) for these elegant gowns. According to ... an end on July 26, 2014. , He ...
Breaking Medicine News(10 mins):Health News:Phthalic Anhydride Market Projected to Reach $8.42 Billion by 2018 – Report by MarketsandMarkets 2Health News:Phthalic Anhydride Market Projected to Reach $8.42 Billion by 2018 – Report by MarketsandMarkets 3Health News:Phthalic Anhydride Market Projected to Reach $8.42 Billion by 2018 – Report by MarketsandMarkets 4Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 4Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 4Health News:Kawartha Lakes Fit Body Boot Camp’s Successful Fat Loss Challenge Results in $2,000 to Boys and Girls Club 2Health News:Kawartha Lakes Fit Body Boot Camp’s Successful Fat Loss Challenge Results in $2,000 to Boys and Girls Club 3Health News:VogueQueen.com Updates Its Summer Collection With New And Trendy Evening Dresses 2
... (HealthDay News) -- An estimated 50 percent to 55 percent ... according to the Society for Vascular Surgery. "More than ... can lead to more serious health problems," Dr. Eva Rzucidlo, ... society news release. "The first line of management for ...
... News) -- Updated vaccines for rotavirus -- once the leading ... appear to increase the risk of potentially deadly side effects, ... taken off the market in 1999 after it was associated ... versions of the vaccine were reintroduced in 2006 and 2008, ...
... 13 (HealthDay News) -- Due to a growing number of ... for Disease Control and Prevention has issued a reminder that ... person. Using insulin pens on more than one person ... as hepatitis viruses and HIV, which causes AIDS, the agency ...
... become an accepted way to simplify a complex array of ... is an independent disease in itself. However, the truth is ... factors at work explaining the symptoms. This is also one ... do not bring the hoped result," says Kari Tikkinen, MD, ...
... , FRIDAY, Jan. 13 (HealthDay News) -- Women with normal ... methotrexate in the first trimester either miscarried or gave birth ... study suggest. An ectopic pregnancy is one where the ... the fetus cannot grow normally and will not survive. The ...
... more routinely digitized to aid interpretation, a software program ... Health System is proving its utility. In a ... Quantization (SIVQ) was able to separate malignancy from background ... type of bladder cancer whose features can vary widely ...
Cached Medicine News:Health News:Recent Rotavirus Vaccines Safe, Study Says 2Health News:CDC Warns Against Sharing Insulin Pens 2Health News:The concept of 'overactive bladder' serves better commercial rather than patient interests 2Health News:Normal Pregnancies May Be Misdiagnosed as Ectopic 2Health News:Software for analyzing digital pathology images proving its usefulness 2Health News:Software for analyzing digital pathology images proving its usefulness 3
(Date:7/10/2014)... Ariz. , July 10, 2014   Ventana ...  Group, today announced it has entered into an agreement ... which operates as EMD Serono in the ... , to collaborate with Merck KGaA,s biopharmaceutical division on ... for an undisclosed target using Ventana,s proprietary diagnostic assays. ...
(Date:1/15/2014)... Sono-Tek Corporation (OTC BB: SOTK) today announced sales of  ... to sales of $2,202,000 for the prior year period, an ... also shown growth over the preceding quarter,s sales, continuing a ... year. Markets that experienced sales increases over the prior year ...
(Date:1/15/2014)... 2014 AARP Foundation today announced it has established a ... the severe cold weather that has gripped much of the ... in need; so to support these emergency relief efforts AARP ... which could mean up to $500,000 in aid. The matching ...
Breaking Medicine Technology:Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 3Sono-Tek Announces Third Quarter Results 2Sono-Tek Announces Third Quarter Results 3Sono-Tek Announces Third Quarter Results 4AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3
Innotrac Aio! immunoanalyzers are specially designed to exploit the benefits of Innotrac Diagnostics' exclusive dry chemistry and non-enhancement time-resolved fluorometry....
... The new Synchron LXi 725 ... technology with highly accurate immunoassay testing ... sample handling on a single platform. ... are automatically repeated for optimal quality ...
...
...
Medicine Products: