Navigation Links
UCSD receives $10 million NIH grant to lead hypoxia tolerance research study

Gabriel G. Haddad, MD, chair of the Department of Pediatrics at the University of California, San Diego School of Medicine and Physician-in-Chief at Rady Children's Hospital-San Diego has received a $10 million grant from the National Institute of Health's Heart, Lung and Blood Institute.

A world renowned physician-scientist in pediatric pulmonary medicine, Haddad will lead a collaborative team of investigators from UC San Diego and the Sanford-Burnham Medical Research Institute to study the impact of low oxygen levels on cells and tissue in the heart, lung, and brain.

"Understanding the molecular, cellular, and genetic mechanisms that contribute to low oxygen tolerance or susceptibility will have a major impact on our treatments of central nervous system and cardio-respiratory diseases such as stroke, myocardial ischemia/infarction, obstructive sleep apnea and pulmonary hypertension," said Haddad.

The overall aims of this project are:

  • To study the adaptive mechanisms to hypoxia in cardiovascular and respiratory systems at both cellular and molecular levels
  • To study the fundamental genetic mechanisms of tolerance in a Drosophila (fruit fly) model
  • To modulate or manipulate molecular mechanisms in mammalian cells/tissues/animals to render them hypoxia-tolerant after learning from a tolerant organism, e.g., the fly
  • To identify molecular signatures of hypoxia tolerance and susceptibility that may be predictive clinically


Contact: Debra Kain
University of California -- San Diego

Page: 1

Related medicine news :

1. NACDD Receives Two-Year Grant From Merck & Co., Inc. to Improve Diabetes Education
2. Dr Yaghouti of Global Laser Vision Receives Patient's Choice Award for 2009
3. UT researcher receives $2.4 million to research obesity, high-risk pregnancy
4. Receives Award for Customer Trust
5. Corporate Wellness Firm Limeade Receives SAS 70 Type II Report
6. Oridion Receives Frost & Sullivan's 2010 Customer Value Enhancement Award
7. Special Olympics Georgia Receives Grant from The Home Depot Foundation
8. NOVAVAX, Inc. Receives NASDAQ Non-Compliance Letter
9. WuXi PharmaTech Receives AAALAC Accreditation for Suzhou Toxicology Facility
10. Verdan Receives Patent on Crystal Deodorant Spray
11. Thomas E. Mower Meets With Dalai Lama; Receives Prestigious Champion Award from Whole Child International
Post Your Comments:
(Date:11/24/2015)... ... ... Willey , has answered a new calling – to relieve snoring and sleep apnea for ... and sleep apnea through oral appliance therapy. He is one of a number ... of four in the Illinois area. , Dr. Willey’s location is at 11825 ...
(Date:11/24/2015)... ... November 24, 2015 , ... Dr. Kevin Day, local ... help the community stress less this holiday season. During the Indiana winter months, ... people's lives and the team at AlignLife want to help provide the tools needed ...
(Date:11/24/2015)... OR (PRWEB) , ... November 24, 2015 , ... Dehydration, ... too much body water to perspiration in the hot sun, and heat stroke and ... Fresh water advocate and radio host Sharon Kleyne. Every cell, system and structure requires ...
(Date:11/24/2015)... ... , ... There’s nothing better than giving the gift of green this holiday ... , This year, gardens are popping up in the most unexpected places. A variety ... Gardens’ African Keyhole Garden Bed ($499) , Water conscious gardeners – and that should ...
(Date:11/24/2015)... ... November 24, 2015 , ... Tudore Tranquility is a new restaurant in Tokyo, ... plant-based fine dining menu that is full of flavorful and creative dishes that exceed ... wedding dinner or a small intimate event. The décor looks stunning with gold and ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Abaxis, Inc. (NasdaqGS: ABAX ), a ... the medical, research, and veterinary markets worldwide, announced today ... present at the 27 th Annual Piper Jaffray ... a.m. ET. The conference will be held at The ... City . Abaxis, Inc. is a ...
(Date:11/24/2015)... Edelris announce today that they have ... Poxel, CNRS, UCBL and ENS-Lyon on a new treatment to ... Hepatitis B virus (HBV) infection is a major public ... worldwide, 20 to 40% of them being at risk of ... existence of an effective preventive vaccine, the HBV infection is ...
(Date:11/24/2015)... MONROVIA, Calif. , Nov. 24, 2015 ... company developing engineered monoclonal antibodies for the treatment of ... announced that Bassil Dahiyat , Ph.D., president and ... in December: , 2015 Piper Jaffray Healthcare ... ET Location: New York, NY ...
Breaking Medicine Technology: