Navigation Links
UCLA study shows metformin is safe for patients with advanced heart failure and diabetes mellitus
Date:1/7/2010

A new study has shown that metformin, a drug often used in the treatment of diabetes mellitus, is safe for use in treating patients who have both diabetes and advanced heart failure. The study was published in the Journal of Cardiac Failure by researchers at the David Geffen School of Medicine at UCLA and is now online (http://www.onlinejcf.com/article/S1071-9164(09)01132-4/abstract).

"There may be over two million individuals with heart failure and type II diabetes mellitus in the U. S. alone, so this important finding will have fairly broad impact," said Dr. Tamara Horwich, senior author of the study and an assistant professor of medicine in the division of cardiology at the David Geffen School of Medicine at UCLA.

Previous studies have shown that diabetes increases not only the risk of developing heart failure, but also the risk of death among heart failure patients. This is due in large part to the fact that diabetes, because it increases the amounts of sugar and fat circulating in the bloodstream, accelerates the onset of coronary atherosclerosis. This hardening and thickening of blood vessels is the hallmark of atherosclerotic heart disease, the most common cause of death in the country. The optimal treatment for high glucose and fat blood levels among heart failure patients has not been demonstrated.

The new study involved 401 patients of an average age of 56, with type II diabetes and advanced systolic heart failure. This patient cohort was followed for 14 years in a comprehensive heart failure management program.

The study results suggest that, in patients with both advanced heart failure and diabetes, use of metformin is safe, and may be associated with better heart failure survival.

"The diabetes drug metformin previously carried a "black box warning" from the FDA against its use in treating diabetes in heart failure
'/>"/>

Contact: Rachel Champeau
rchampeau@mednet.ucla.edu
310-794-2270
University of California - Los Angeles
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2015)... March 29, 2015 The Claudia ... Women’s Cancer announce today that Dr. Beth Y. ... the Claudia Cohen Research Foundation Prize for Outstanding Gynecologic ... Society of Gynecologic Oncology 46th Annual Meeting on Women's ... the Cedars-Sinai Women’s Cancer Program at the Samuel Oschin ...
(Date:3/29/2015)... (PRWEB) March 29, 2015 At ... platform provides basic health information around medical ... to discuss these challenges as well as helping ... Link addresses six medical conditions using evidenced based ... to engage in conversations around them., ...
(Date:3/29/2015)... (PRWEB) March 29, 2015 North American ... PT Online Continuing Education Courses . ... hours of CME - TPTA, approval # 56399TX      ... evaluation of the shoulder complex - 10.5 hours - ... #56400TX , Examination and Treatment of the SI Joint ...
(Date:3/28/2015)... Coffee could not only perk you up in ... disease, researchers have found. , They found that those who ... antioxidants. Antioxidants fight gum disease. Does coffee, then, help fight ... Henry M. Goldman School of Dental Medicine explored in a ... the Journal of Periodontology. , “This is the first long-term ...
(Date:3/28/2015)... 2015 Take a bite of warm, ... action. Acids tumble into the stomach, ready to break ... structure lets these acids run amok, triggering a burning ... symptom. More than 60 million Americans have heartburn at ... heartburn starts, and how it can be stopped. , ...
Breaking Medicine News(10 mins):Health News:Dr. Beth Y. Karlan Named Recipient of the Claudia Cohen Research Foundation Prize for Outstanding Gynecologic Cancer Researcher 2015 2Health News:Dr. Beth Y. Karlan Named Recipient of the Claudia Cohen Research Foundation Prize for Outstanding Gynecologic Cancer Researcher 2015 3Health News:Dr. Beth Y. Karlan Named Recipient of the Claudia Cohen Research Foundation Prize for Outstanding Gynecologic Cancer Researcher 2015 4Health News:Krame Health Solutions Announces Release of AfroHealthLink, an Interactive Health Resource Center Tailored to Individuals of African & Caribbean Descent Around the World 2Health News:Krame Health Solutions Announces Release of AfroHealthLink, an Interactive Health Resource Center Tailored to Individuals of African & Caribbean Descent Around the World 3Health News:New Research Impliments Coffee May Help Fight Gum Disease and Increasing Benefits With Tylers Coffee 2Health News:Bypass Your Heartburn Worries This Easter With Tylers Coffee 2
... paranoid about heart disease. One survey said that of all ... disease. Whenever people get to read something on heart disease, ... at times over trivial problems based on the assumption that ... in Austria says that chronic infections can predispose to heart ...
... wandered into a neighbor’s backyard and was later found curled ... stiff and her heart had stopped beating. , When she ... but lo and behold, she was awake and smiling on ... , The temperature outside was –24 degree Celsius and the ...
... just begun. After waging wars over many drug formulations the ... ball was set in motion by the dramatic announcement of ... would cost less than a U.S. dollar a day. Not ... of its own production of anti retroviral drugs for AIDS ...
... “in thing” in the treatment of strokes according to a report ... cells from the cord blood could heal strokes almost 80% faster ... yet to be worked out and the project itself is in ... Dr. Paul R. Sanberg from the university of South Florida conducted ...
... reeling under the shock waves of a rebound epidemic of HIV ... doubled in most areas and in some select high-risk pockets of ... are even higher. And what is the cause for this sudden ... HIV infection in the area has made the high risk gay ...
... word from Gujarat is that doctors are being stretched to ... break. At times they work in candlelight when the power ... deliver babies were conducted in open verandahs. On Jan 27th ... fractures were fixed without x- rays. ,The worst ...
Cached Medicine News:
(Date:3/27/2015)...  Holographic Optical Technologies of Augusta, Georgia ... imaging, is entering the world of consumer electronics with ... 20 th , 2015, the campaign will introduce the ... 22-inch displays will allow consumers to view fully three ... addition to the two displays, the company will also ...
(Date:3/27/2015)... 27, 2015 The Temple Health & Bioscience District ... 5,000-square-foot building at 1802 South First St. in the Temple ... the City of Temple to receive ... the Central Texas Veterans Health Care System, the new facility ... early stage biotechnology and life science companies. ...
(Date:3/27/2015)... -- Zimmer Holdings, Inc. (NYSE and SIX: ZMH) is celebrating a key ... Complete Knee System. , ... Zimmer first introduced the NexGen knee system, with its innovative ... million implantations of the NexGen knee have taken place worldwide. ... knee demonstrates the importance of design innovation and component quality for surgeons ...
Breaking Medicine Technology:Holographic Optical Technologies brings cutting-edge holograms to consumer market through upcoming Kickstarter campaign 2Holographic Optical Technologies brings cutting-edge holograms to consumer market through upcoming Kickstarter campaign 3Temple Health & Bioscience District Relocates, Offers Office And Lab Space To Biotech Companies 2Zimmer Celebrates Key Milestones For NexGen Complete Knee System 2
... Reportlinker.com announces that a new market research report ... European Markets for Video, High-Tech and Integrated OT ... The European Markets for Video, ... includes Austria, Benelux, France, Germany, Italy, Portugal, Scandinavia, ...
... Aethlon Medical, Inc. (OTC Bulletin Board: ... to address infectious disease and cancer, announced today that ... U.S. Department of Health and Human Services BARDA Industry ... presentation entitled: "A Broad Spectrum Antiviral Platform Technology" is ...
Cached Medicine Technology:Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 2Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 3Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 4Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 5Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 6Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 7Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 8Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 9Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 10Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 11Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 12Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 13Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 14Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 15Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 16Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 17Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 18Reportlinker Adds European Markets for Video, High-Tech and Integrated OT Equipment 2011 19Aethlon Medical Announces Presentation at U.S. Department of Health and Human Services BARDA Industry Day 2Aethlon Medical Announces Presentation at U.S. Department of Health and Human Services BARDA Industry Day 3Aethlon Medical Announces Presentation at U.S. Department of Health and Human Services BARDA Industry Day 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: