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UCLA study reveals how genes interact with their environment to cause disease
Date:2/18/2010

genetic makeup," said first author Casey Romanoski, a UCLA graduate student in human genetics. "About 35 percent of the most affected genes were influenced by the interaction between their genetic variants and the fats."

"You can't effectively study genes divorced from their environment," she added. "The missing link lies in the intersection of genes with their environment."

"Our findings demonstrate that these interactions are important in humans and should be considered in genetic research," said Lusis. "Improving our understanding of the molecular architecture of disease may one day provide us with a new tool for how we address common disorders like cancer, diabetes and heart disease."


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Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles
Source:Eurekalert

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