Navigation Links
UCLA stem cell scientists reprogram human skin cells into embryonic stem cells
Date:2/11/2008

UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells without using embryos or eggs.

Led by scientists Kathrin Plath and William Lowry, UCLA researchers used genetic alteration to turn back the clock on human skin cells and create cells that are nearly identical to human embryonic stem cells, which have the ability to become every cell type found in the human body. Four regulator genes were used to create the cells, called induced pluripotent stem cells or iPS cells.

The UCLA study confirms the work first reported in late November of researcher Shinya Yamanaka at Kyoto University and James Thompson at the University of Wisconsin. The UCLA research appears Feb. 11, 2008, in an early online edition of the journal Proceedings of the National Academy of the Sciences.

The implications for disease treatment could be significant. Reprogramming adult stem cells into embryonic stem cells could generate a potentially limitless source of immune-compatible cells for tissue engineering and transplantation medicine. A patients skin cells, for example, could be reprogrammed into embryonic stem cells. Those embryonic stem cells could then be prodded into becoming various cells types beta islet cells to treat diabetes, hematopoetic cells to create a new blood supply for a leukemia patient, motor neuron cells to treat Parkinsons disease.

Our reprogrammed human skin cells were virtually indistinguishable from human embryonic stem cells, said Plath, an assistant professor of biological chemistry, a researcher with the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and lead author of the study. Our findings are an important step towards manipulating differentiated human cells to generate an unlimited supply of patient specific pluripotent stem cells. We are very excited about the potential implications.

The UCLA work was comp
'/>"/>

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Scientists Reprogram Human Skin Cells Into Embryonic Stem Cells
2. Scientists from Europe, Israel and the US develop robotic rats to aid in rescue missions
3. Childrens Hospital scientists identify possible target for prevention and treatment of pneumonia
4. NIAID scientists identify new cellular receptor for HIV
5. ECNP launches research grant for young scientists
6. Scientists confirm new virus responsible for deaths of transplant recipients in Australia
7. Bonn scientists simulate dinosaur digestion in the lab
8. Scripps scientists peg wind as the force behind fish booms and busts
9. Chemical signature of manic depression discovered by scientists
10. Bug guts map brings scientists closer to understanding different bugs role in the body
11. Scripps scientists find calcium channel blockers help normalize lysosomal storage disease cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... December 19, 2014 The Hermitage ... club in Southern Vermont’s Deerfield Valley, announced today that ... by classic rock songs. , Three time Grammy ... a private concert followed by a trail naming ceremony. ... trail names include: “I’m Alright” the theme song for ...
(Date:12/19/2014)... The tragic death from "rat-bite fever" of a 10-year-old San ... according to a report from the U.S. Centers for Disease ... potentially fatal illness that should be considered in persons with ... rodent exposure is reported," said a team led by Dr. ... case outlined in the report occurred in August of 2013. ...
(Date:12/19/2014)... Traveling through the same U.S. airport gate, one infected ... a four-hour time span, illustrating just how easily the ... exposures in this report were not prolonged and occurred ... the fact that measles is highly contagious," wrote a ... at the U.S. Centers for Disease Control and Prevention. ...
(Date:12/17/2014)... While countless companies tempt patients to buy hCG ... of their purchase. Not only is the sale of hCG ... patients who buy hCG online are typically receiving products that ... real hCG present. Illegal internet hCG is typically manufactured outside ... and may contain unknown fillers that can pose very serious ...
(Date:12/17/2014)... Providence, RI (PRWEB) December 17, 2014 ... nationally recognize private practices that have made outstanding ... and in support and progression of private practice ... the American Physical Therapy Association. , On behalf ... DPT, OCS, owner and CEO of Performance accepted ...
Breaking Medicine News(10 mins):Health News:The Hermitage Club Officially Names Four Ski Trails after Iconic Rock Songs by Grammy Award Winner Kenny Loggins 2Health News:Scratch From Pet Rat Kills Child; CDC Warns of Risk 2Health News:Arriving Now at Gate 42: Measles 2Health News:Arriving Now at Gate 42: Measles 3Health News:Diet Doc Reveals the Real Dangers for Those who Buy hCG Online 2Health News:Diet Doc Reveals the Real Dangers for Those who Buy hCG Online 3Health News:Performance Physical Therapy Awarded with Jayne L. Snyder Private Practice of the Year 2014 2
... InfoLogix,s e-Learning Team Develops Custom, Web-Based Training Solution ... Jan. 22 InfoLogix, Inc. (Nasdaq: ... of enterprise mobility and advanced wireless asset tracking ... today it has successfully deployed an advanced clinical ...
... and by male and female doctors, study finds , , ... heart failure is influenced by the gender of the ... evaluated 1,857 patients and the treatment records of 829 ... less likely to receive guideline-recommended medications, such as angiotensin-converting ...
... Clinic today announced the launch of its culture blog, Sharing Mayo ... and employees to share their stories about what makes Mayo Clinic ... ... -- Mayo Clinic today announced the launch of its culture blog, ...
... Initiatives, Inc. (Nasdaq: MTXX ), an over-the-counter ... consumers with "Better Ways to Get Better(R)," announced today ... ended December 31, 2008, will be released after the ... conference call will be held the following morning on ...
... a Difficult Target for Pharmaceutical Companies Wishing to Grow ... From Decision ResourcesWALTHAM, Mass., Jan. 22 /PRNewswire/ -- ... and advisory firms focusing on pharmaceutical and healthcare issues, ... ranks fourth in the number of untreated HIV patients ...
... Jan. 22 In 2008, The Larry King Cardiac,Foundation, ... individuals with no health insurance, increased the number of ... and continued to expand its,national network of partner hospitals. ... funds into individual medical procedures,the Foundation helped save the ...
Cached Medicine News:Health News:InfoLogix Develops Organizational Development and Mobility Training Solution for Edward Hospital 2Health News:InfoLogix Develops Organizational Development and Mobility Training Solution for Edward Hospital 3Health News:Gender May Influence Heart Failure Treatment 2Health News:Mayo Clinic Announces Sharing Mayo Clinic Blog for Patients, Employees 2Health News:Mayo Clinic Announces Sharing Mayo Clinic Blog for Patients, Employees 3Health News:Mayo Clinic Announces Sharing Mayo Clinic Blog for Patients, Employees 4Health News:Matrixx Initiatives, Inc. Sets Time for Discussion of Third Quarter Fiscal 2009 Financial Results 2Health News:Georgia Ranks Fourth in the Number of Untreated HIV Patients in the United States 2Health News:Georgia Ranks Fourth in the Number of Untreated HIV Patients in the United States 3Health News:2008 a Year of Growth and Unprecedented Service for The Larry King Cardiac Foundation 2Health News:2008 a Year of Growth and Unprecedented Service for The Larry King Cardiac Foundation 3
(Date:12/17/2014)... , Dec. 17, 2014 Royal Philips ... (NASDAQ: VOLC ), a global leader in catheter-based ... they have entered into a definitive merger agreement. Pursuant to ... all of the issued and outstanding shares of Volcano for ... of USD 1 billion (approx. EUR 800 million), to be ...
(Date:12/17/2014)... 17, 2014 With advancements in neurological ... market is seeing new growth, according to Kalorama ... account for the majority of market volume, newer ... images, which are creating opportunities for more sophisticated applications. ... growing at a rate of 4%, with world ...
(Date:12/17/2014)...  RXi Pharmaceuticals Corporation (NASDAQ: RXII ... and commercializing innovative therapies addressing major unmet medical ... in its first Phase 2a study, RXI-109-1301.  The ... 1-month findings that were reported in September of ... http://photos.prnewswire.com/prnh/20130917/NE80755LOGO , , , ...
Breaking Medicine Technology:Philips to acquire Volcano to expand global leadership position in image-guided therapy market 2Philips to acquire Volcano to expand global leadership position in image-guided therapy market 3Philips to acquire Volcano to expand global leadership position in image-guided therapy market 4Philips to acquire Volcano to expand global leadership position in image-guided therapy market 5Philips to acquire Volcano to expand global leadership position in image-guided therapy market 6Philips to acquire Volcano to expand global leadership position in image-guided therapy market 7Philips to acquire Volcano to expand global leadership position in image-guided therapy market 8Kalorama: 3T Advancements Bringing New Growth to the MRI Market 2Kalorama: 3T Advancements Bringing New Growth to the MRI Market 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 2RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 3RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 4RXi Pharmaceuticals Announces Sustained Effect of RXI-109 at Three Months Post Scar Revision Surgery and the Completion of Enrollment for its Phase 2a Trial RXI-109-1301 5
... Light Sciences Oncology, Inc.,(LSO) today announced that it ... (BPH), or enlargement of the prostate, using Light,Infusion ... LSO plans to conduct a 12-patient, Phase I/II,dose-escalation ... as well as a,40-patient, Phase IIa study in ...
... Inc. (OTC,Bulletin Board: GOVX), an Atlanta based, ... and treatment of infectious,diseases, today provided an ... Phase 2 preventative human clinical trial testing ... with its AIDS vaccine. Five,successful human trials ...
Cached Medicine Technology:Light Sciences Oncology Begins Clinical Trials of Litx Therapy in Patients with Enlarged Prostate 2Light Sciences Oncology Begins Clinical Trials of Litx Therapy in Patients with Enlarged Prostate 3GeoVax Reports Progress on Its AIDS Vaccine Technology 2GeoVax Reports Progress on Its AIDS Vaccine Technology 3GeoVax Reports Progress on Its AIDS Vaccine Technology 4GeoVax Reports Progress on Its AIDS Vaccine Technology 5
... easy-to-use solution that's perfectly suited to environments ... light weight and mobility mean that the ... position. It can also be easily mounted ... syndrome" is minimized through the use of ...
... for the Induction Room., ,The Aestiva/5 ... Room. The Aestiva/5 Induction has similar user ... helps make it easier for clinicians to ... pneumatic gas mixing, O2 failure alarm, N2O ...
... new level of excellence and economy., ... delivery system with basic ventilation at a ... excellence of the Aestiva/5 Anesthesia System - ... - it features a configurable version of ...
... An integrated approach to quality patient ... is an innovative approach to anesthesia delivery. ... it combines enhanced ventilation features, electronically controlled ... monitoring and information management to create a ...
Medicine Products: