Navigation Links
UCLA stem cell scientists reprogram human skin cells into embryonic stem cells
Date:2/11/2008

UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells without using embryos or eggs.

Led by scientists Kathrin Plath and William Lowry, UCLA researchers used genetic alteration to turn back the clock on human skin cells and create cells that are nearly identical to human embryonic stem cells, which have the ability to become every cell type found in the human body. Four regulator genes were used to create the cells, called induced pluripotent stem cells or iPS cells.

The UCLA study confirms the work first reported in late November of researcher Shinya Yamanaka at Kyoto University and James Thompson at the University of Wisconsin. The UCLA research appears Feb. 11, 2008, in an early online edition of the journal Proceedings of the National Academy of the Sciences.

The implications for disease treatment could be significant. Reprogramming adult stem cells into embryonic stem cells could generate a potentially limitless source of immune-compatible cells for tissue engineering and transplantation medicine. A patients skin cells, for example, could be reprogrammed into embryonic stem cells. Those embryonic stem cells could then be prodded into becoming various cells types beta islet cells to treat diabetes, hematopoetic cells to create a new blood supply for a leukemia patient, motor neuron cells to treat Parkinsons disease.

Our reprogrammed human skin cells were virtually indistinguishable from human embryonic stem cells, said Plath, an assistant professor of biological chemistry, a researcher with the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and lead author of the study. Our findings are an important step towards manipulating differentiated human cells to generate an unlimited supply of patient specific pluripotent stem cells. We are very excited about the potential implications.

The UCLA work was comp
'/>"/>

Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Scientists Reprogram Human Skin Cells Into Embryonic Stem Cells
2. Scientists from Europe, Israel and the US develop robotic rats to aid in rescue missions
3. Childrens Hospital scientists identify possible target for prevention and treatment of pneumonia
4. NIAID scientists identify new cellular receptor for HIV
5. ECNP launches research grant for young scientists
6. Scientists confirm new virus responsible for deaths of transplant recipients in Australia
7. Bonn scientists simulate dinosaur digestion in the lab
8. Scripps scientists peg wind as the force behind fish booms and busts
9. Chemical signature of manic depression discovered by scientists
10. Bug guts map brings scientists closer to understanding different bugs role in the body
11. Scripps scientists find calcium channel blockers help normalize lysosomal storage disease cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... TX (PRWEB) July 13, 2014 The Pearland, ... children ranging in age from four months to 12 years ... and karate classes to birthday parties and Summer Camps, is ... Little Gym of Pearland after spending over six ... of roles, including Gym Director. , Berry has over ...
(Date:7/13/2014)... Recently, MyDressCity.com, one of the most popular suppliers of ... its new range of elegant Quinceanera dresses . ... discounted prices. Worldwide clients can enjoy this special offer ... online shop, there are plenty of beautiful dresses for ... materials. MyDressCity.com’s hot items are prom gowns, bridesmaid gowns, ...
(Date:7/13/2014)... 13, 2014 According to the Kidney Disease ... step by step guide on what to do to eliminate ... quickly. Vkool writes in its review that readers can easily ... to revitalize their kidney health. Vkool also informs in its ... reverse their damaged kidney functions naturally. The book consists of ...
(Date:7/13/2014)... Hope Palliative & Hospice Care announced today that they will ... Senior Living Community in Palatine, IL. The group, called “New ... Wednesdays of every month. This group will begin on ... 55 S. Greeley St. Palatine, IL 60067. It is ... for the group. , “A grief support group is ...
(Date:7/12/2014)... 13, 2014 According to the new ... Systems, Airborne Systems, and Naval Systems) - Global Forecasts ... Security and Surveillance Radar market are estimated to be ... a CAGR of 5.97% to reach $8.61 billion by ... with 47 figures spread through 161 pages and in-depth ...
Breaking Medicine News(10 mins):Health News:The Little Gym of Pearland, TX Now Under New Ownership and Management 2Health News:Cheap Elegant Quinceanera Dresses Unveiled by MyDressCity.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 3Health News:Hope Hospice Announces Grief Support Group at the Tamarack Senior Living Community 2Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 4
... a startling find. Around 75 percent of whites or those ... of developing heart diseases. And that’s not all. These genes ... diabetes. ,The findings, made by two independent groups of ... even if they do not have clear risk factors such as ...
... American doctor has threatened to mobilise US congressmen and senators ... Information (RTI) Act in a case relating to his crusade ... Saha, whose wife died of alleged wrongful treatment in India ... my senators and congressmen in US and will ask them ...
... Human Resource Development in collaboration with National AIDS Control ... Adolescence Education Programme (AEP) which is being implemented by ... ,The Programme is aimed at the ... of the major concerns, i.e. process of growing up ...
... that can enable the blind to hear what they cannot see ... texts through an embedded system and converts them into voice that ... can only read text, but later it is likely to pick ... that took six months to develop the device and the software ...
... to detect epidemic diseases has entered the phase of clinical ... methods that rely on antigen or antibody test, the new ... DNA or RNA, to confirm epidemic diseases such as hepatitis ... Centre of US National Institutes of Health (NIH). ...
... and women who consumed higher levels of calcium and vitamin ... brain lesions, regions of damage// that can increase risk of ... Payne and her co-investigators from Duke and the University of ... men and women (79 men, 153 women) between the ages ...
Cached Medicine News:Health News:Gene Mutations Leave Caucasians Prone To Heart Diseases And Diabetes 2Health News:NRI Threatens to Move US Congress for Justice in India 2Health News:Higher Intake of Calcium and Vitamin D Linked With Brain Lesions in Older People 2
(Date:7/10/2014)... Calif. , July 10, 2014 Integrated ... leader in advanced memory and analog IC solutions, today ... on Thursday, July 24, 2014, at 7:00 a.m. Pacific ... financial results for the fiscal 2014 third quarter ended ... call via telephone, dial 1-888-556-4997 before 6:50 a.m. Pacific ...
(Date:7/10/2014)...  Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... the sale to Galderma of all rights to Restylane, ... Valeant for $1.4 billion in cash, pursuant to the ... its acquisition of Galderma. "We are ... a company that is firmly committed to the aesthetic ...
(Date:7/10/2014)... R.I. , July 10, 2014 CVS Caremark ... board of directors has approved a quarterly dividend of $0.275 ... dividend is payable on August 1, 2014, to holders of ... CVS Caremark is dedicated to helping people ... pharmacy company in the United States . ...
Breaking Medicine Technology:
... Calif., Oct. 10 Amgen (Nasdaq:  AMGN) today ... pivotal Phase 3 trials comparing denosumab to Zometa® ... the prevention of skeletal related events (SREs) in ... separate analyses, denosumab demonstrated a clinically meaningful, consistent ...
... Oct. 8 The American Dental Association (ADA) has ... ), the largest provider of health care products and ... at $860,000 to students in the Community Dental Health ... initially for hands-on clinical training in the program, which ...
Cached Medicine Technology:Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 2Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 3Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 4Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 5Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 6Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 7Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 8Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 9Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 10Henry Schein Inc. Donates Equipment to ADA Community Dental Health Coordinator Pilot Program 2Henry Schein Inc. Donates Equipment to ADA Community Dental Health Coordinator Pilot Program 3
... The Asnis III™ Cannulated Screw System has ... and TCS Systems and combined them to ... screws in both titanium and stainless steel. ... System is designed to optimize surgical outcomes ...
The 6.5mm cannulated cancellous ACE SCFE Screw is specifically designed for the treatment of slipped capital femoral epiphysis. The ACE SCFE Screw simplifies insertion and facilitates removal....
... a wide variety of cannulated screw products. ... partially threaded and fully threaded versions. , ... and 7.0 mm products. These incorporate innovative ... a little easier. Ratchet screwdrivers have proven ...
Biomet® Arthrodesis Nail indications include: , Failed external fixation , Aseptic failed total knee arthroplasty , Periarticular fractures where repair is not possible , Limb salvage in tumor...
Medicine Products: