Navigation Links
UCLA researchers eliminate major roadblock in regenerative medicine
Date:1/25/2011

ug Administration supervision.

"It is also the first defined medium to allow for long term single-cell passage," said the paper's senior author, Hong Wu, the David Geffen Professor of Molecular and Medical Pharmacology at the David Geffen School of Medicine at UCLA and a researcher with UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research.

Single-cell passaging a process in which hES cells are dissociated into single cells and subcultured through single-cellderived colonies is important in overcoming the massive cell death associated with hES cell dissociation during routine passage, and it allows for genetic manipulation at the clonal level.

"Although other studies have demonstrated growth of hES cells under defined media formulations and/or on defined surfaces, to the best of our knowledge, this is the first study that combines defined cultures with routine single-cell passaging, which plays an important role in supplying a large mass of clinically applicable cells," said Hideaki Tsutsui, a UCLA postdoctoral scholar and lead author of the study. "Thus, our hES cell culture system, guided by the FSC technique, will bring hES cells one step closer to clinical therapies."

Initially, the very large number of small molecules in the culture medium and their unknown synergistic effects made it difficult for researchers to assess the proper concentration of each for achieving long-term expansion of hES cells. The major challenge was to find the best way to sort out those molecules and rapidly determine the best combinatorial concentrations.

The breakthrough, ultimately, was the product of a close interdisciplinary collaboration.

Tsutsui, then a UCLA Engineering graduate student, and Bahram Valamehr, then a graduate student at the Geffen School of Medicine, started working on the project two years ago. Armed with biological readouts and analyses of stem cells mastered in Hong
'/>"/>

Contact: Wileen Wong Kromhout
wwkromhout@support.ucla.edu
310-206-0540
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Researchers use cell profiling to detect abnormalities -- including cancer
2. Workplace noise-related hearing loss affects sleep quality -- Ben Gurion U. researchers
3. Researchers reveal function of novel molecule that underlies human deafness
4. WSU researchers apply fatigue model to fatal commuter air crash
5. U-M researchers find indirect path to attack breast cancer stem cells
6. Researchers unzip MRSA and discover route for vaccine
7. Researchers discover way to halt lung inflammation in animal models
8. LA BioMed researchers among Americas Top Doctors
9. Researchers find rising levels of hypertension in older Mexican-Americans
10. Robotic surgery of tremendous benefit to patients, say JGH researchers
11. UBC-VCH researchers find critical link between Down syndrome and Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... Vegas, NV (PRWEB) August 22, 2014 ... content that is written by marketing experts for marketers ... affiliate links has caught the attention of Shane Michaels, ... involved with Internet marketing in any way knows that ... failure in the industry,” reports Michaels. “But even though ...
(Date:8/22/2014)... Buying a policy for different life insurance products can ... coverage types by insurers in the U.S. The Quotes Pros ... the public using its sortable tool at http://quotespros.com/life-insurance.html . ... is expected to promote the discounts and special offerings for ... The system is designed to help an adult locate a ...
(Date:8/22/2014)... 2014 Millennium Treatment Group has recently noticed ... high level of drug use among teenagers. The treatment facility ... addiction and work to minimize drug abuse. , America is ... drug addiction in history. According to the National Institute ... Americans aged 12 or older—or 9.2 percent of the population—had ...
(Date:8/22/2014)... Amy Norton HealthDay ... -- A growing number of Americans on work disability ... study. Researchers found that between 2007 and 2011, ... Insurance benefits were prescribed narcotic painkillers each year. And ... percent in 2007 to 23 percent in 2011. ...
(Date:8/22/2014)... Many Americans know little about how Ebola is transmitted and ... the United States, a new survey shows. About four ... be a major Ebola outbreak in the United States, and ... will get sick with the deadly virus in the next ... poll. However, those opinions don,t match reality, the Harvard ...
Breaking Medicine News(10 mins):Health News:My Writers: Review Exposes Online Source for Quality Marketing Content 2Health News:Principal Life Insurance Policies Now Quoted for Adults at Insurance Website Online 2Health News:Millennium Treatment Group Sees Increase in Marijuana Use Among Youth 2Health News:Many U.S. Workers on Disability Use Narcotic Painkillers, Study Finds 2Health News:Many U.S. Workers on Disability Use Narcotic Painkillers, Study Finds 3Health News:Many U.S. Workers on Disability Use Narcotic Painkillers, Study Finds 4Health News:Many Americans Harbor Unfounded Fears About Ebola Outbreak: Survey 2
... Life & Health Insurance Company (ELH), a subsidiary of Eastern ... that it will add vision to the ELH line of ... plan and a vision discount program, both utilizing the VSP ... product portfolio enables employers to offer one of the most ...
... Dec. 29 Dynatronics Corporation (Nasdaq: DYNT ) ... filed by NASDAQ with the SEC, gives the company ... $1 per share minimum bid rule."We are pleased that ... light of the current market environment," stated Kelvyn H. ...
... may help spread the word about warfarin,s possible complications ... pamphlet has been published to help Spanish-speaking patients understand ... blood thinner warfarin. , Millions of Americans take warfarin, ... an irregular heartbeat (known as atrial fibrillation), they,ve had ...
... Latest bid to force TomoTherapy to consider strategic alternativesMADISON, Wis., ... Avalon Capital Group, announced that on December 23, 2008 it ... TomoTherapy Inc. (Nasdaq: TOMO ). This step is ... value for the company,s shareholders in the wake of the ...
... widespread media attention given to studies that have indicated ... new study shows just one-third of children who are ... pediatrician. The study, led by researchers at The ... Medicine in Cleveland, also stresses that this failure to ...
... drug use higher among those whose families don,t accept ... young adults whose families rejected them when they were ... sex, illegal drug use and suicide attempts, new research ... negative reaction to a child,s sexuality directly causes problems ...
Cached Medicine News:Health News:Eastern Life & Health Introduces New Vision Product 2Health News:Eastern Life & Health Introduces New Vision Product 3Health News:NASDAQ Gives Dynatronics a Second Three-Month Extension for Minimum Bid Price Compliance 2Health News:Guide on Blood Thinner Now Available in Spanish 2Health News:Avalon Portfolio Nominates Slate of Directors for TomoTherapy Board 2Health News:Avalon Portfolio Nominates Slate of Directors for TomoTherapy Board 3Health News:Can't chalk it up to 'baby fat' 2Health News:Rejection of Gay Teens Linked to Later Troubles 2Health News:Rejection of Gay Teens Linked to Later Troubles 3
(Date:8/21/2014)... 2014  Decision Resources Group finds that, for ... Brazil and Mexico ... prescribe long-acting beta-agonist (LABA)- and long-acting muscarinic antagonist ... current severe cost/coverage constraints. Therefore, new brands of ... launch in these countries—which will considerably expand the ...
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- ScriptPro ... Alliance (HITRUST) under its Common Security Framework (CSF). ... Security and Privacy Manager, "We appreciate this rigorous, ... of commitment that this certification signifies. Our business ... ABOUT THE CSF CERTIFICATION PROCESS: ScriptPro,s internal ...
(Date:8/21/2014)... BreedIT Corp., (OTCQB: BRDT) ... worldwide license holder and distributor of highly sophisticated ... today is pleased to announce the formation of ... a leading Israeli medical Cannabis breeder. ... breeds of medical Cannabis to meet the requests ...
Breaking Medicine Technology:Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 2Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 3ScriptPro Achieves HITRUST Certification 2BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 2BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 3BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 4
Titanium. Straight shafts with 6 mm platform and Pierse tips. Flat serrated handle with dull finish....
0.5 mm, 1 x 2 teeth set at 45 degrees. Serrated handle with polished finish....
5 mm tying platform, serrated cross action handle with polished finish. Teeth: 0.10 mm, 1 x 2 set at 90 degrees....
0.12 mm, 1 x 2 teeth. Serrated handle with polished finish....
Medicine Products: