Navigation Links
UCLA researchers combat global disease with a cell phone, Google Maps and a lot of ingenuity
Date:4/27/2012

In the fight against emerging public health threats, early diagnosis of infectious diseases is crucial. And in poor and remote areas of the globe where conventional medical tools like microscopes and cytometers are unavailable, rapid diagnostic tests, or RDTs, are helping to make disease screening quicker and simpler.

RDTs are generally small strips on which blood or fluid samples are placed. Specific changes in the color of the strip, which usually occur within minutes, indicate the presence of infection. Different tests can be used to detect various diseases, including HIV, malaria, tuberculosis and syphilis.

While the advantages of RDTs are significant better disease-management, more efficient surveillance of outbreaks in high-risk areas and the ability of minimally trained technicians to test large number of individuals they can also present problems.

"Conventional RDTs are currently read manually, by eye, which is prone to error, especially if various different types of tests are being used by the health care worker," said Aydogan Ozcan, a UCLA professor of electrical engineering and bioengineering.

To address such challenges, Ozcan and his colleagues from the UCLA Henry Samueli School of Engineering and Applied Science and the California NanoSystems Institute at UCLA have developed a compact and cost-effective RDT-reading device that works in tandem with standard cell phones.

"What we have created is a digital 'universal' reader for all RDTs, without any manual decision-making," he said.

The RDT-reader attachment, which clips onto a cell phone, weighs approximately 65 grams and includes an inexpensive lens, three LED arrays and two AAA batteries. The platform has the ability to read nearly every type of RDT. An RDT strip is inserted into the attachment, and with the help of cell phone's existing camera unit and a special smart-phone application, the strip is converted into a digital image.

The platform then rapidly reads the digitized RTD image to determine, first, whether the test is valid and, second, whether the results are positive or negative, thus eliminating the potential errors that can occur with a human reader, especially one administering multiple tests of various test types. And because the color changes in RDTs don't last more than a few hours in the field, the ability to store the digitized image indefinitely provides an added benefit.

After this step, the RDT-reader platform wirelessly transmits the results of the tests to a global server, which processes them, stores them and, using Google Maps, creates maps charting the spread of various diseases and conditions both geographically and over time throughout the world.

Together, the universal RDT reader and the mapping feature, which have been implemented on both iPhones and Android-based smart-phones, could significantly increase our ability to track emerging epidemics worldwide and aid in epidemic preparedness, the researchers say.

"This platform would be quite useful for global health professionals, as well as for policymakers, to understand causeeffect relationships at a much larger scale for combating infectious diseases," Ozcan said.

The research is published in the journal Lab on a Chip.

Additional authors of the study include Onur Mudanyali (first author), Stoyan Dimitrov, Uzair Sikora, Swati Padmanabhan, and Isa Navruz, all of the department of electrical engineering at the UCLA Henry Samueli School of Engineering and Applied Science.

Ozcan and his UCLA research team have been developing a variety of cell-phone attachments that utilize the digital components already embedded in standard cell phones to aid in the fight against global disease. With more than 5 billion cell-phone subscribers around the world today, cell phones can play a central role in telemedicine applications, and existing wireless telecommunications infrastructure presents new opportunities for innovative cloud-based health-monitoring and management platforms, the researchers say.


'/>"/>
Contact: Jennifer Marcus
jmarcus@cnsi.ucla.edu
310-267-4839
University of California - Los Angeles
Source:Eurekalert

Related medicine news :

1. Spinal cord injury researchers win Apple Award for article on niacin for dyslipidemia
2. Moffitt researchers find cancer therapies affect cognitive functioning among breast cancer survivors
3. Gene Behind Psoriasis Identified, Researchers Say
4. McMaster researchers find potential for new uses of old drug
5. Football helmet sensors help researchers demystify concussion in young athletes
6. Researchers Repair Damage Caused by Heart Attacks in Mice
7. University of Cincinnati researchers win $3.7M grant from US Department of Defense
8. Researchers Develop Blood Test for Depression
9. Researchers ID Genes That May Determine Mental Illness
10. Researchers Map Brain Regions Linked to Intelligence
11. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... ... April 29, 2016 , ... Intellitec Solutions will be ... to 18th at the Broward County Convention Center. The event is a chance ... best practices in public facility management. Intellitec Solutions will highlight their customized accounting ...
(Date:4/29/2016)... ... ... Pro3rd Grunge is a package of 30 grunge-themed lower thirds created for ... and locations without having to set a single keyframe. Choose from a variety of ... Simply select a preset and drag it into the FCPX timeline. Let ...
(Date:4/29/2016)... ... , ... The number of chronically and seriously ill individuals is growing. Americans ... urgent need for highly skilled care managers and care coordinators. Care Excellence ... and retain care managers, and enhance their skills. , Care Excellence helps ...
(Date:4/29/2016)... ... April 29, 2016 , ... Orthodontics Limited, ... founders, Dr. Gemmi and Dr. Middleberg, were asked by Invisalign to ... During the seminar, titled “Advancing the Biomechanics of Invisalign Clear Aligners,” Dr. ...
(Date:4/28/2016)... Petersburg, FL (PRWEB) , ... April 29, 2016 , ... Sublime Beauty® is offering a ... the same product) for 50% off. The discount is applied to the product with lesser ... is given to those who purchase $250 or more in products. , "So many women ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... April 27, 2016  Hologic, Inc. (Nasdaq: ... results for the fiscal second quarter ended March ... of $0.24 increased 41.2%, and non-GAAP diluted EPS ... increased 5.8% on a reported basis, and 6.3% ... "We posted another good quarter, highlighted by 14.6% ...
(Date:4/27/2016)...   , Total Sales Grow ... Clinical sales grow 16% year-over-year  , ... MKEAY) inventor of Cellvizio®, the multidisciplinary confocal laser endomicroscopy ... ended March 31, 2016 and provided an update on ... First Quarter 2016 Revenue Results by Category  ...
(Date:4/27/2016)... Conn. , April 27, 2016   ... of its digital health technology platform, which specializes ... and programs into scalable digital products, Zillion enables ... engagement and empower consumers to take control of ... face-to-face live video conferencing – including one-to-one, group ...
Breaking Medicine Technology: